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Author Details

Zhengfang Yi
The Institute of Biomedical Sciences, East China Normal University
2002
114
41
PMIDPaper TitleJournal TitlePublished Year
38086269WB518, a novel STAT3 inhibitor, effectively alleviates IMQ and TPA-induced animal psoriasis by inhibiting STAT3 phosphorylation and Keratin 17.Int Immunopharmacol2024
36374556Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic Cancer.Clin Cancer Res2023
37634473A small molecule BCL6 inhibitor as chemosensitizers in acute myeloid leukemia.Biomed Pharmacother2023
38054798Discovery of a Highly Potent and Selective MYOF Inhibitor with Improved Water Solubility for the Treatment of Gastric Cancer.J Med Chem2023
37143950Combined treatment of disulfiram with PARP inhibitors suppresses ovarian cancer.Front Oncol2023
37334274Preclinical characterization of WB737, a potent and selective STAT3 inhibitor, in natural killer/T-cell lymphoma.MedComm (2020)2023
34740924Single-Cell Analysis Reveals EP4 as a Target for Restoring T-Cell Infiltration and Sensitizing Prostate Cancer to Immunotherapy.Clin Cancer Res2022
35476936Discovery of 2-Amino-3-cyanothiophene Derivatives as Potent STAT3 Inhibitors for the Treatment of Osteosarcoma Growth and Metastasis.J Med Chem2022
36103247Discovery of a Novel Potent STAT3 Inhibitor HP590 with Dual p-Tyr<sup>705</sup>/Ser<sup>727</sup> Inhibitory Activity for Gastric Cancer Treatment.J Med Chem2022
36165130Discovery of 1,5-diaryl-1,2,4-triazole derivatives as myoferlin inhibitors and their antitumor effects in pancreatic cancer.Future Med Chem2022
35121048A novel small-molecule activator of unfolded protein response suppresses castration-resistant prostate cancer growth.Cancer Lett2022
34990752An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo.Cancer Lett2022
33420372Targeting STAT3 by a small molecule suppresses pancreatic cancer progression.Oncogene2021
33634965A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression.Clin Transl Med2021
33687738The natural product trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer.Br J Pharmacol2021
34150618Regression of Castration-Resistant Prostate Cancer by a Novel Compound HG122.Front Oncol2021
33283987Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer.EMBO Mol Med2021
33420488Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.Nat Cell Biol2021
32168548Determining the Drug-Like Properties of Ailanthone, a Novel Chinese Medicine Monomer with Anti-CRPC Activity.Planta Med2020
35025480A Mussel-Inspired Extracellular Matrix-Mimicking Composite Scaffold for Diabetic Wound Healing.ACS Appl Bio Mater2020
31758659Ethyl-N-dodecanoyl-l-arginate hydrochloride combats pathogens with low-resistance generation by membrane attack and modifies gut microbiota structure.Microb Biotechnol2020
31812467Synthesis and anticancer activity of novel 9,13-disubstituted berberine derivatives.Bioorg Med Chem Lett2020
32078862Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane.Eur J Med Chem2020
31895575Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of <i>N</i>-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth.J Med Chem2020
31952596Characterization and optimization of production of bacterial cellulose from strain CGMCC 17276 based on whole-genome analysis.Carbohydr Polym2020
32002708Regression of castration-resistant prostate cancer by a novel compound QW07 targeting androgen receptor N-terminal domain.Cell Biol Toxicol2020
31972471Corrigendum to 'Inhibition of HDACs-EphA2 signaling axis with WW437 demonstrates promising preclinical antitumor activity in breast cancer' [EBioMedicine 31 (2018) 276-286].EBioMedicine2020
32216291Copper-Based Metal-Organic Framework as a Controllable Nitric Oxide-Releasing Vehicle for Enhanced Diabetic Wound Healing.ACS Appl Mater Interfaces2020
32382484Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression.Adv Sci (Weinh)2020
30638240Diastereoselective synthesis of 3,3-disubstituted 3-nitro-4-chromanone derivatives as potential antitumor agents.Org Biomol Chem2019
35528914Synthesis and biological evaluation of 3-nitro-4-chromanone derivatives as potential antiproliferative agents for castration-resistant prostate cancer.RSC Adv2019
35520707Discovery of methylpyrimidine ring-fused diterpenoid analogs as a novel testosterone synthesis promoter.RSC Adv2019
35016283Space-Oriented Nanofibrous Scaffold with Silicon-Doped Amorphous Calcium Phosphate Nanocoating for Diabetic Wound Healing.ACS Appl Bio Mater2019
31640758A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer.J Exp Clin Cancer Res2019
31553023An aligned porous electrospun fibrous scaffold with embedded asiatic acid for accelerating diabetic wound healing.J Mater Chem B2019
30835100Correction to Electrospun Micropatterned Nanocomposites Incorporated with Cu<sub>2</sub>S Nanoflowers for Skin Tumor Therapy and Wound Healing.ACS Nano2019
30709873Correction: Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway.Cancer Res2019
31091478Synthesis and biological evaluation of methylpyrimidine-fused tricyclic diterpene analogs as novel oral anti-late-onset hypogonadism agents.Eur J Med Chem2019
31026162Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin.J Med Chem2019
30572284Chinese sesame stick-inspired nano-fibrous scaffolds for tumor therapy and skin tissue reconstruction.Biomaterials2019
29454159An aligned porous electrospun fibrous membrane with controlled drug delivery - An efficient strategy to accelerate diabetic wound healing with improved angiogenesis.Acta Biomater2018
30213946A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer.Nat Commun2018
30429953Synthesis of Cyanoenone-Modified Diterpenoid Analogs as Novel Bmi-1-Mediated Antitumor Agents.ACS Med Chem Lett2018
30452224Correction to Copper Silicate Hollow Microspheres-Incorporated Scaffolds for Chemo-Photothermal Therapy of Melanoma and Tissue Healing.ACS Nano2018
29518321Copper Silicate Hollow Microspheres-Incorporated Scaffolds for Chemo-Photothermal Therapy of Melanoma and Tissue Healing.ACS Nano2018
29759486Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer.EBioMedicine2018
28713016A conducive bioceramic/polymer composite biomaterial for diabetic wound healing.Acta Biomater2017
32263946A patterned nanocomposite membrane for high-efficiency healing of diabetic wound.J Mater Chem B2017
28257652Ailanthone: a new potential drug for castration-resistant prostate cancer.Chin J Cancer2017
28194552A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling.Sci China Life Sci2017
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Collaborators

The Institute of Biomedical Sciences, East China Normal University
Co-authored papers 88
Shanghai Changzheng Hospital
Co-authored papers 4
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Princess Margaret Cancer Center/University Health Network
Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Obstetrics and Gynecology Hospital of Fudan University
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Center for Genomic and Personalized Medicine, Guangxi Medical University
Co-authored papers 1
Shanghai Changhai Hospital
Co-authored papers 1
Novel Bioinformatics Co.
Co-authored papers 1
University of Washington
Co-authored papers 1
Anhui University of Science & Technology
Co-authored papers 1
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Texas A&M Health Science Center Institute of Biosciences and Technology
Co-authored papers 1
University of California los angeles
Co-authored papers 1
Sackler School of Medicine, Tel Aviv University
Co-authored papers 1
Novel Bioinformatics Co.
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China University of Geosciences
Co-authored papers 1
University of Toronto, Princess Margaret Cancer Centre
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Princess Margaret Cancer Centre, University Health Network
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University Health Network, University of Toronto
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Fudan University Shanghai Cancer Center
Co-authored papers 1
Co-authored papers 1
Shanghai Changhai Hospital
Co-authored papers 1
Fudan University Shanghai Cancer Center
Co-authored papers 1
Cedars-Sinai Medical Center
Co-authored papers 1
Beijing Friendship Hospital, Capital Medical University
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