Author details

Full Name

Zhenyu Xuan

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35731926	PRC2 Heterogeneity Drives Tumor Growth in Medulloblastoma.	Cancer Research	2022
34644528	A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development.	Cell	2021
34260936	Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation.	Cell Reports	2021
33253789	Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma.	Cancer Letters	2021
33420191	DNA sequences performs as natural language processing by exploiting deep learning algorithm for the identification of N4-methylcytosine.	Scientific Reports	2021
34758315	Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes.	Cell Rep	2021
32945124	G-Quadruplexes act as sequence-dependent protein chaperones.	EMBO Reports	2020
28025178	MTGIpick allows robust identification of genomic islands from a single genome.	Brief Bioinform	2018
30467350	Neuroprotection by Heat Shock Factor-1 (HSF1) and Trimerization-Deficient Mutant Identifies Novel Alterations in Gene Expression.	Scientific Reports	2018
29386106	Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.	Cell Rep	2018
29343685	The protective role of DOT1L in UV-induced melanomagenesis.	Nat Commun	2018
28082412	Deficiency of microRNA <i>miR-34a</i> expands cell fate potential in pluripotent stem cells.	Science	2017
28548087	The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.	Nat Commun	2017
28841410	In Situ Capture of Chromatin Interactions by Biotinylated dCas9.	Cell	2017
28442406	Anti-amnesic effect of extract and alkaloid fraction from aerial parts of Peganum harmala on scopolamine-induced memory deficits in mice.	Journal of Ethnopharmacology	2017
28607157	Anaerobic Cysteine Degradation and Potential Metabolic Coordination in Salmonella enterica and Escherichia coli.	Journal of Bacteriology	2017
27982722	TargetLink, a new method for identifying the endogenous target set of a specific microRNA in intact living cells.	RNA Biology	2017
27190130	The Swi3 protein plays a unique role in regulating respiration in eukaryotes.	Bioscience Reports	2016
27065321	SMARCA4/Brg1 coordinates genetic and epigenetic networks underlying Shh-type medulloblastoma development.	Oncogene	2016
27060148	De novo deciphering three-dimensional chromatin interaction and topological domains by wavelet transformation of epigenetic profiles.	Nucleic Acids Res	2016
26329581	The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.	Sci Signal	2015
33758771	SCT Promoter Methylation is a Highly Discriminative Biomarker for Lung and Many Other Cancers.	IEEE Life Sci Lett	2015
25995611	Prioritization of cancer-related genomic variants by SNP association network.	Cancer Informatics	2015
24637302	PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism.	Cellular Signalling	2014
23664764	Epigenomic analysis of multilineage differentiation of human embryonic stem cells.	Cell	2013
24036441	Long non-coding RNAs and complex human diseases.	International Journal of Molecular Sciences	2013
24137534	A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis.	Elife	2013
24278370	Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures.	PLoS ONE	2013
23826102	Complete genome analysis of three Acinetobacter baumannii clinical isolates in China for insight into the diversification of drug resistance elements.	PLoS ONE	2013
22228832	A highly efficient and effective motif discovery method for ChIP-seq/ChIP-chip data using positional information.	Nucleic Acids Res	2012
23251452	New fusion transcripts identified in normal karyotype acute myeloid leukemia.	PLoS ONE	2012
21868675	Chaperonins facilitate KNOTTED1 cell-to-cell trafficking and stem cell function.	Science	2011
21310084	Estimating developmental states of tumors and normal tissues using a linear time-ordered model.	BMC Bioinformatics	2011
21304545	Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection.	Heredity	2011
21423206	The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.	Oncogene	2011
21283513	Estimating the quality of reprogrammed cells using ES cell differentiation expression patterns.	PLoS ONE	2011
20448179	Targeted investigation of the Neandertal genome by array-based sequence capture.	Science	2010
20940252	Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells.	Journal of Cell Science	2010
20729808	A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.	EMBO Journal	2010
21190591	Understanding protein evolutionary rate by integrating gene co-expression with protein interactions.	BMC Syst Biol	2010
20368986	Deep sequencing of target linkage assay-identified regions in familial breast cancer: methods, analysis pipeline and troubleshooting.	PLoS One	2010
18997002	High-resolution human core-promoter prediction with CoreBoost_HM.	Genome Research	2009
19645219	Pharmacokinetics of forsythoside after intravenous administration in beagle dogs.	European Journal of Drug Metabolism and Pharmacokinetics	2009
19736251	Updates to the RMAP short-read mapping software.	Bioinformatics	2009
19581485	High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing.	Genome Res	2009
19478811	Hybrid selection of discrete genomic intervals on custom-designed microarrays for massively parallel sequencing.		2009
19657104	Sensitive and accurate detection of copy number variants using read depth of coverage.	Genome Res	2009
19416867	The transcriptome of human CD34+ hematopoietic stem-progenitor cells.	Proceedings of the National Academy of Sciences of the United States of America	2009
19800577	Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.	Cancer Cell	2009
19786836	Investigating repetitively matching short sequencing reads: the enigmatic nature of H3K9me3.	Epigenetics	2009