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Author Details

Larry J W Miercke
University of California San Francisco
1989
39
28
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
25081744Tetra detector analysis of membrane proteins.Curr Protoc Protein Sci2014
20534468Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems.Proc Natl Acad Sci U S A2010
21049926Tandem facial amphiphiles for membrane protein stabilization.J Am Chem Soc2010
20855585Structural context shapes the aquaporin selectivity filter.Proc Natl Acad Sci U S A2010
19061901Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening.J Mol Biol2009
19360018A general protocol for the crystallization of membrane proteins for X-ray structural investigation.Nat Protoc2009
19383790Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance.Proc Natl Acad Sci U S A2009
18500352Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum.Nat Struct Mol Biol2008
15684085De novo design of an IL-4 antagonist and its structure at 1.9 A.Proc Natl Acad Sci U S A2005
14646142Water and glycerol permeation through the glycerol channel GlpF and the aquaporin family.J Synchrotron Radiat2004
15377788The channel architecture of aquaporin 0 at a 2.2-A resolution.Proc Natl Acad Sci U S A2004
15361618Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A.Science2004
12629974The glycerol facilitator GlpF its aquaporin family of channels, and their selectivity.Adv Protein Chem2003
12948772Glycerol facilitator GlpF and the associated aquaporin family of channels.Curr Opin Struct Biol2003
14630323Selectivity and conductance among the glycerol and water conducting aquaporin family of channels.FEBS Lett2003
12575934Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase.Structure2003
12614156Structure of human pro-chymase: a model for the activating transition of granule-associated proteases.Biochemistry2003
11964478Control of the selectivity of the aquaporin water channel family by global orientational tuning.Science2002
29973827Encoding Selectivity of a Transmembrane Channel.ScientificWorldJournal2002
12429097Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway.Structure2002
11532442Atomic structure of a glycerol channel and implications for substrate permeation in aqua(glycero)porins.FEBS Lett2001
11752428Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel.Proc Natl Acad Sci U S A2001
11039922Structure of a glycerol-conducting channel and the basis for its selectivity.Science2000
10890912Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding.Proc Natl Acad Sci U S A2000
10545282Expression, purification, and structural characterization of the bacteriorhodopsin-aspartyl transcarbamylase fusion protein.Protein Expr Purif1999
9548741Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation.Biochemistry1998
9406555A designed four helix bundle protein with native-like structure.Nat Struct Biol1997
8218256Secondary structure analysis of purified functional CHIP28 water channels by CD and FTIR spectroscopy.Biochemistry1993
8448142Bacteriorhodopsin D85N: three spectroscopic species in equilibrium.Biochemistry1993
8241409Two-dimensional crystallization of Escherichia coli-expressed bacteriorhodopsin and its D96N variant: high resolution structural studies in projection.Biophys J1993
8235592Structure at 2.5 A of a designed peptide that maintains solubility of membrane proteins.Science1993
1892824Effects of Asp-96----Asn, Asp-85----Asn, and Arg-82----Gln single-site substitutions on the photocycle of bacteriorhodopsin.Biochemistry1991
2062880Resonance Raman spectra of bacteriorhodopsin mutants with substitutions at Asp-85, Asp-96, and Arg-82.Photochem Photobiol1991
1993191Effects of detergent environments on the photocycle of purified monomeric bacteriorhodopsin.Biochemistry1991
1848786Wild-type and mutant bacteriorhodopsins D85N, D96N, and R82Q: purification to homogeneity, pH dependence of pumping, and electron diffraction.Biochemistry1991
2007142Wild-type and mutant bacterioopsins D85N, D96N, and R82Q: high-level expression in Escherichia coli.Biochemistry1991
2713415Isoelectric focusing studies of bacteriorhodopsin.Biochim Biophys Acta1989
2560474Preparative purification of functional bacteriorhodopsin by high-performance size-exclusion chromatography.J Chromatogr1989
2708376Purification of bacteriorhodopsin and characterization of mature and partially processed forms.J Biol Chem1989
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Collaborators

University of California San Francisco
Co-authored papers 37
Department of Pharmaceutical Chemistry, University of California-San Francisco
Co-authored papers 11
University of California san francisco
Co-authored papers 8
University of California berkeley
Co-authored papers 5
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University of California san francisco
Co-authored papers 2
University of Oklahoma Health Sciences Center
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Albert Einstein College of Medicine
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University of Virginia
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University of California San Francisco
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Pfizer Inc.
Co-authored papers 1
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Betty Irene Moore School of Nursing at the University of California davis
Co-authored papers 1
St. Jude Children's Research Hospital
Co-authored papers 1
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Co-authored papers 1
Center for the Structure of Membrane Proteins, University of California san francisco
Co-authored papers 1
Vagelos College of Physicians and Surgeons, Columbia University
Co-authored papers 1
University of Illinois at Urbana-Champaign
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California san francisco
Co-authored papers 1