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Author Details

Alexander F A Keszei
Princess Margaret Cancer Center, University Health Network
2012
14
10
PMIDPaper TitleJournal TitlePublished Year
37308485Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.Nat Commun2023
37546794Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes.bioRxiv2023
35859168Cryo-EM structure of an active bacterial TIR-STING filament complex.Nature2022
34403584Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.J Am Chem Soc2021
34887561Structural insights into metazoan pretargeting GET complexes.Nat Struct Mol Biol2021
34644530Cyclic CMP and cyclic UMP mediate bacterial immunity against phages.Cell2021
31634471Structural and Functional Analysis of Ubiquitin-based Inhibitors That Target the Backsides of E2 Enzymes.J Mol Biol2020
32544385CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.Cell2020
31011209Mechanism for recycling tRNAs on stalled ribosomes.Nat Struct Mol Biol2019
28115697Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases.Proc Natl Acad Sci U S A2017
26344097Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function.Mol Cell2015
24248594Structure of an SspH1-PKN1 complex reveals the basis for host substrate recognition and mechanism of activation for a bacterial E3 ubiquitin ligase.Mol Cell Biol2014
21929567Signalling and sex in the social amoebozoans.Biol Rev Camb Philos Soc2012
22065585Conserved structural mechanisms for autoinhibition in IpaH ubiquitin ligases.J Biol Chem2012
  • 1 - 14 of 14

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Collaborators

Mike Tyers
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 2
Albert J R Heck
Utrecht University
Co-authored papers 1
Danny Vesprini
University of Toronto, Canada Odette Cancer Centre
Co-authored papers 1
Mohit Jain
Cumming School of Medicine, University of Calgary, 0 Hospital Drive NW
Co-authored papers 1
Michelle R Downes
University of Toronto
Co-authored papers 1
Vladimir Ignatchenko
Margaret Cancer Center
Co-authored papers 1
Andrew Macklin
Margaret Cancer Center
Co-authored papers 1
Lydia Y Liu
University of Toronto
Co-authored papers 1
Oliver J Semmes
Eastern Virginia Medical School
Co-authored papers 1
Julius O Nyalwidhe
Eastern Virginia Medical School
Co-authored papers 1
Zhuyu Qiu
Co-authored papers 1
Thomas Kislinger
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 1
Stanley K Liu
Odette Cancer Centre, University of Toronto
Co-authored papers 1
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
Co-authored papers 1
Meinusha Govindarajan
Princess Margaret Cancer Center, University Health Network
Co-authored papers 1
Brian P Main
Leroy T. Canoles Jr. Cancer Research Center, Eastern Virginia Medical School
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Matthew Waas
Present address: Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Raymond S Lance
Washington State University Elson S. Floyd College of Medicine
Co-authored papers 1
Li-Fang Yang
Guangxi Minzu University
Co-authored papers 1
Amanda Khoo
Princess Margaret Cancer Centre
Co-authored papers 1
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