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Author Details

Madeline R Luth
University of California San Diego
2017
24
11
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37995692Antiplasmodial peptaibols act through membrane directed mechanisms.Cell Chem Biol2024
36919909Human Polo-like Kinase Inhibitors as Antiplasmodials.ACS Infect Dis2023
37546892Reaction hijacking inhibition of <i>Plasmodium falciparum</i> asparagine tRNA synthetase.Res Sq2023
37737220Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance.Elife2023
37197802Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.Br J Pharmacol2023
36888694Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target.Sci Transl Med2023
34348113Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.Cell Chem Biol2022
35653481Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.Science2022
36260689The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple <i>Plasmodium</i> kinases and life cycle stages.Sci Transl Med2022
36008486Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.Nat Commun2022
35149760Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance.Commun Biol2022
34460304The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.Antimicrob Agents Chemother2021
33715347PfMFR3: A Multidrug-Resistant Modulator in <i>Plasmodium falciparum</i>.ACS Infect Dis2021
32286267Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway.Nat Commun2020
32078764Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials.ACS Infect Dis2020
33064992SnapShot: Antimalarial Drugs.Cell2020
31170268Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents.PLoS Pathog2019
31806760Evolution of resistance in vitro reveals mechanisms of artemisinin activity in <i>Toxoplasma gondii</i>.Proc Natl Acad Sci U S A2019
31801884In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model.Sci Transl Med2019
29451780Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery.ACS Infect Dis2018
30523084Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.Science2018
30373366Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome.J Med Chem2018
27889151Efficacy of post-harvest rinsing and bleach disinfection of E. coli O157:H7 on spinach leaf surfaces.Food Microbiol2017
29284029CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).PLoS Negl Trop Dis2017
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Collaborators

Elizabeth A Winzeler
University of California San Diego
Co-authored papers 21
Sabine Ottilie
University of California San Diego
Co-authored papers 14
Dyann F Wirth
The Broad Institute
Co-authored papers 6
Amanda K Lukens
Harvard T.H. Chan School of Public Health
Co-authored papers 6
Matthew Abraham
University of California
Co-authored papers 5
Case W McNamara
a division of The Scripps Research Institute La Jolla
Co-authored papers 3
Manu Vanaerschot
Columbia University Irving Medical Center
Co-authored papers 3
Andrea L Cheung
University of California
Co-authored papers 3
Krypton Carolino
University of California
Co-authored papers 2
Edgar Vigil
University of California
Co-authored papers 2
Gregory M Goldgof
University of California san francisco
Co-authored papers 2
Prianka Kumar
The George Washington University School of Medicine and Health Sciences
Co-authored papers 2
Jennifer Yang
Chang Gung Memorial Hospital
Co-authored papers 2
Luke Whitesell
University of Toronto
Co-authored papers 1
Leah E Cowen
University of Toronto
Co-authored papers 1
Jacob D Durrant
University of Pittsburgh
Co-authored papers 1
Edward L Huttlin
Harvard Medical School
Co-authored papers 1
Reysha Patel
University of California
Co-authored papers 1
William H Gerwick
Scripps Institution of Oceanography, University of California San Diego
Co-authored papers 1
Emmanuelle LeBlanc
University of Toronto
Co-authored papers 1
Stuart A Ralph
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
Co-authored papers 1
Yoshiyuki Suzuki
Nagoya City University
Co-authored papers 1
Steven P Gygi
Harvard Medical School
Co-authored papers 1
Gisel Lopez
University of California
Co-authored papers 1
Karla P Godinez-Macias
University of California
Co-authored papers 1
Yingyao Zhou
Genomics Institute of the Novartis Research Foundation
Co-authored papers 1
Roy M Williams
University of California
Co-authored papers 1
Felicia Gunawan
University of California
Co-authored papers 1
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 1
Udo Oppermann
Botnar Research Centre, University of Oxford
Co-authored papers 1
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