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Author Details

Jason K Sa
Korea University, College of Medicine
2015
50
18
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36915208Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.Genome Med2023
37792958Identifying predictors of glioma evolution from longitudinal sequencing.Sci Transl Med2023
37788099The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling.JCI Insight2023
36972629Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.Neoplasia2023
34738209Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells.Stem Cell Rev Rep2022
35666535Somatic genomic landscape of East Asian epithelial ovarian carcinoma and its clinical implications from prospective clinical sequencing: A Korean Gynecologic Oncology Group study (KGOG 3047).Int J Cancer2022
35657027Recapitulated Crosstalk between Cerebral Metastatic Lung Cancer Cells and Brain Perivascular Tumor Microenvironment in a Microfluidic Co-Culture Chip.Adv Sci (Weinh)2022
35994815Calcipotriol, a synthetic Vitamin D analog, promotes antitumor immunity via CD4+T-dependent CTL/NK cell activation.Biomed Pharmacother2022
35882469Corrigendum to "Combination effect of poly (ADP-ribose) polymerase inhibitor and DNA demethylating agents for treatment of epithelial ovarian cancer" [Gynecologic Oncology, Volume 165, Issue 2, May 2022, Pages 270-280].Gynecol Oncol2022
36009433Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer's Disease.Biomedicines2022
35067843Correction to: Effects of Long-Term In Vitro Expansion on Genetic Stability and Tumor Formation Capacity of Stem Cells.Stem Cell Rev Rep2022
35305818Combination effect of poly (ADP-ribose) polymerase inhibitor and DNA demethylating agents for treatment of epithelial ovarian cancer.Gynecol Oncol2022
34986867Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune signature benefit from pembrolizumab: results from a single-arm phase 2 trial.Genome Med2022
34862196Genomic Landscape and Clinical Utility in Korean Advanced Pan-Cancer Patients from Prospective Clinical Sequencing: K-MASTER Program.Cancer Discov2022
33479772Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma.Brain2021
33494793Comprehensive molecular characterization of gastric cancer patients from phase II second-line ramucirumab plus paclitaxel therapy trial.Genome Med2021
33828082Mutation-specific non-canonical pathway of PTEN as a distinct therapeutic target for glioblastoma.Cell Death Dis2021
33846173Determinants of Response and Intrinsic Resistance to PD-1 Blockade in Microsatellite Instability-High Gastric Cancer.Cancer Discov2021
31096737Clinical Targeted Next-Generation sequencing Panels for Detection of Somatic Variants in Gliomas.Cancer Res Treat2020
32070411Comprehensive pharmacogenomic characterization of gastric cancer.Genome Med2020
32636318A Phase II Trial of Tipifarnib for Patients with Previously Treated, Metastatic Urothelial Carcinoma Harboring <i>HRAS</i> Mutations.Clin Cancer Res2020
32605068Multi-Habitat Radiomics Unravels Distinct Phenotypic Subtypes of Glioblastoma with Clinical and Genomic Significance.Cancers (Basel)2020
32794373Ethnic delineation of primary glioblastoma genome.Cancer Med2020
32620753Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities.Nat Commun2020
32847614Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma.Genome Biol2020
32753598MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.Nat Commun2020
32532977ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages.Nat Commun2020
30536544Hypermutagenesis in untreated adult gliomas due to inherited mismatch mutations.Int J Cancer2019
31748746Longitudinal molecular trajectories of diffuse glioma in adults.Nature2019
31850215Systematic Evaluation of Gastric Tumor Cell Index and Two-Drug Combination Therapy via 3-Dimensional High-Throughput Drug Screening.Front Oncol2019
29939324Identification of genomic and molecular traits that present therapeutic vulnerability to HGF-targeted therapy in glioblastoma.Neuro Oncol2019
30085274Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma.Neuro Oncol2019
30898893PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma.J Exp Med2019
31044160The combination of neoantigen quality and T lymphocyte infiltrates identifies glioblastomas with the longest survival.Commun Biol2019
30804471Ly6G<sup>+</sup> inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model.Cell Death Differ2019
29129044Anti-SEMA3A Antibody: A Novel Therapeutic Agent to Suppress Glioblastoma Tumor Growth.Cancer Res Treat2018
30202050A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma.Nat Cell Biol2018
30343896Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor.Cell2018
30262818Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy.Nat Genet2018
29573206Identification of transcriptome signature for predicting clinical response to bevacizumab in recurrent glioblastoma.Cancer Med2018
29715102Pharmacokinetics, Biodistribution, and Toxicity Evaluation of Anti-SEMA3A (F11) in <i>In Vivo</i> Models.Anticancer Res2018
29600313Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization.Med Oncol2018
27901492Genomic and transcriptomic characterization of skull base chordoma.Oncotarget2017
28263318Spatiotemporal genomic architecture informs precision oncology in glioblastoma.Nat Genet2017
28754668Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling.Cancer Res2017
28902178Tumor Inhibitory Effect of IRCR201, a Novel Cross-Reactive c-Met Antibody Targeting the PSI Domain.Int J Mol Sci2017
28917835Antitumor activity, pharmacokinetics, tumor-homing effect, and hepatotoxicity of a species cross-reactive c-Met antibody.Biochem Biophys Res Commun2017
26783102Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma.Int J Oncol2016
27102443Anti-miR delivery strategies to bypass the blood-brain barrier in glioblastoma therapy.Oncotarget2016
26023737In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma.Oncotarget2015
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Collaborators

Samsung Medical Center, Sungkyunkwan University School
Co-authored papers 35
Touro College of Osteopathic Medicine
Co-authored papers 17
Institute for Refractory Cancer Research, Samsung Medical Center
Co-authored papers 12
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 11
Lerner Research Institute, Cleveland Clinic
Co-authored papers 10
Cancer Stem Cell Research Center, Samsung Biomedical Research Institute
Co-authored papers 10
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 10
Samsung Medical Center, Sungkyunkwan University
Co-authored papers 9
Korea University College of Medicine
Co-authored papers 9
Gangnam Severance Hospital
Co-authored papers 9
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Co-authored papers 8
Institute for Refractory Cancer Research, Samsung Medical Center
Co-authored papers 7
Children's Hospital Boston
Co-authored papers 7
Samsung Genome Institute, Samsung Medical Center
Co-authored papers 7
Sungkyunkwan University
Co-authored papers 7
Seoul National University, College of Medicine
Co-authored papers 7
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Cancer Stem Cell Research Center, Samsung Biomedical Research Institute
Co-authored papers 6
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 6
Yonsei University College of Medicine, Severance Hospital
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Busan Paik Hospital, Inje University
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Institute of Vision Research, Yonsei University College of Medicine
Co-authored papers 6
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 6
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 6
Inha University
Co-authored papers 5
Research Institute for Future Medicine, Samsung Medical Center
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College of Medicine, Seoul National University
Co-authored papers 5
The Hong Kong University of Science and Technology
Co-authored papers 5
Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan University
Co-authored papers 5
Yale School of Medicine
Co-authored papers 4