Author details

Full Name

Charles B Epstein

Affiliation

ORCID

Career Start Year

1985

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37500887	Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.	Nat Immunol	2023
37034577	Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements.	bioRxiv	2023
35474001	Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.	Nature	2022
33212152	Epigenetic Alterations in Keratinocyte Carcinoma.	J Invest Dermatol	2021
33828297	Genome-wide enhancer maps link risk variants to disease genes.	Nature	2021
32728101	Detecting sample swaps in diverse NGS data types using linkage disequilibrium.	Nat Commun	2020
32728249	Expanded encyclopaedias of DNA elements in the human and mouse genomes.	Nature	2020
31263286	Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.	Nat Med	2019
31501535	Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.	Nat Med	2019
28753427	A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression.	Cell	2017
27826357	Systematic comparison of monoclonal versus polyclonal antibodies for mapping histone modifications by ChIP-seq.	Epigenetics Chromatin	2016
26229090	Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.	Cancer Discov	2015
25503565	Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.	Nat Cell Biol	2015
25363779	Genetic and epigenetic fine mapping of causal autoimmune disease variants.	Nature	2015
25533951	Dissecting neural differentiation regulatory networks through epigenetic footprinting.	Nature	2015
25693563	Integrative analysis of 111 reference human epigenomes.	Nature	2015
25164756	Comparative analysis of metazoan chromatin organization.	Nature	2014
25129075	Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.	Nat Neurosci	2014
24598259	Impact of sequencing depth in ChIP-seq experiments.	Nucleic Acids Res	2014
23333102	Genome-wide chromatin state transitions associated with developmental and environmental cues.	Cell	2013
24076989	Recommendations for the design and analysis of epigenome-wide association studies.	Nat Methods	2013
23664763	Transcriptional and epigenetic dynamics during specification of human embryonic stem cells.	Cell	2013
22726435	DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.	Cell	2012
22955991	ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.	Genome Res	2012
22174693	Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.	PLoS Genet	2011
21441907	Mapping and analysis of chromatin state dynamics in nine human cell types.	Nature	2011
22196736	Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.	Cell	2011
20668531	PTK6 regulates IGF-1-induced anchorage-independent survival.	PLoS One	2010
20852635	Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.	Nat Biotechnol	2010
18022394	SIT4 regulation of Mig1p-mediated catabolite repression in Saccharomyces cerevisiae.	FEBS Letters	2007
15113399	Comparing gene discovery from Affymetrix GeneChip microarrays and Clontech PCR-select cDNA subtraction: a case study.	BMC Genomics	2004
15662205	An empirical Bayesian significance test of cDNA library data.	Journal of Computational Biology	2004
12631716	Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes.	Molecular Biology of the Cell	2003
11855849	Induction of global stress response in Saccharomyces cerevisiae cells lacking telomerase.	Biochemical and Biophysical Research Communications	2002
11222779	Identification of partial loss of function p53 gene mutations utilizing a yeast-based functional assay.	Nucleic Acids Research	2001
11381609	Numerical methods for handling uncertainty in microarray data: an example analyzing perturbed mitochondrial function in yeast.	Methods in Cell Biology	2001
11742997	RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p.	EMBO Journal	2001
11179416	Genome-wide responses to mitochondrial dysfunction.	Molecular Biology of the Cell	2001
11120686	MAD: a suite of tools for microarray data management and processing.	Bioinformatics	2000
10679339	Microarray technology - enhanced versatility, persistent challenge.	Current Opinion in Biotechnology	2000
9572492	p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors.	Oncogene	1998
9131587	A genetic approach to mapping the p53 binding site in the MDM2 protein.	Mol Med	1997
15706764	Impairments of brain and behavior: the neurological effects of alcohol.		1997
8526340	The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype.	Ann N Y Acad Sci	1995
8114735	Genes that can bypass the CLN requirement for Saccharomyces cerevisiae cell cycle START.	Molecular and Cellular Biology	1994
1387626	CLB5: a novel B cyclin from budding yeast with a role in S phase.	Genes and Development	1992
22200474	A method for the estimation of historical sulfate concentrations in natural freshwaters.	Environmental Science & Technology	1988
17812878	Response: Acid deposition in the Western United States.	Science	1986
17777926	Acid deposition, smelter emissions, and the linearity issue in the Western United States.	Science	1985