Author details

Full Name

Pascal D Johann

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36975506	Epigenetic Modification of Mesenchymal Stromal Cells Derived from Bone Marrow and Embryonal Tumors to Facilitate Immunotherapeutic Approaches in Pediatric Malignancies.		2023
37553222	Rhabdoid tumors in patients conceived following ART: is there an association?		2023
37450044	Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics.	Acta Neuropathol	2023
34699462	Cui Bono? Identifying Patient Groups That May Benefit From Granulocyte Transfusions in Pediatric Hematology and Oncology.	J Pediatr Hematol Oncol	2022
35446794	SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome.	Am J Surg Pathol	2022
36291828	Renal Medullary Carcinomas Harbor a Distinct Methylation Phenotype and Display Aberrant Methylation of Genes Related to Early Nephrogenesis.	Cancers	2022
35501487	ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance.	Acta Neuropathol	2022
35565313	Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population.	Cancers (Basel)	2022
36127393	Adult rhabdoid tumors-a riddle inside an enigma?	Modern Pathology	2022
36127323	Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors.	Cell Death Dis	2022
36443295	DNA methylation-based classification of sinonasal tumors.	Nat Commun	2022
36612221	Outcome for Pediatric Adreno-Cortical Tumors Is Best Predicted by the COG Stage and Five-Item Microscopic Score-Report from the German MET Studies.		2022
33283872	Corrigendum to: Molecular subgrouping of atypical teratoid/rhabdoid tumors-a reinvestigation and current consensus.	Neuro Oncol	2022
35318328	Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors.	Nat Commun	2022
35173482	Current and Emerging Therapeutic Approaches for Extracranial Malignant Rhabdoid Tumors.	Cancer Management and Research	2022
35152461	Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC.	Neuropathol Appl Neurobiol	2022
34605902	Treatment and outcome of intracranial ependymoma after first relapse in the 2nd AIEOP protocol.	Neuro Oncol	2022
34931022	Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.	NPJ Precis Oncol	2021
34234357	The drug development pipeline for glioblastoma-A cross sectional assessment of the FDA Orphan Drug Product designation database.	PLoS ONE	2021
33479225	Sarcoma classification by DNA methylation profiling.	Nat Commun	2021
33739782	Atypical Teratoid/Rhabdoid Tumor (AT/RT) With Molecular Features of Pleomorphic Xanthoastrocytoma.	Am J Surg Pathol	2021
34003336	Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors.	Acta Neuropathol	2021
33737307	Relevance of Molecular Groups in Children with Newly Diagnosed Atypical Teratoid Rhabdoid Tumor: Results from Prospective St. Jude Multi-institutional Trials.	Clin Cancer Res	2021
34265800	IDH2 R172 Mutations Across Poorly Differentiated Sinonasal Tract Malignancies: Forty Molecularly Homogenous and Histologically Variable Cases With Favorable Outcome.	Am J Surg Pathol	2021
33938067	Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup.	Brain Pathol	2021
34347371	Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors.	Pediatr Blood Cancer	2021
33135735	Second series by the Italian Association of Pediatric Hematology and Oncology of children and adolescents with intracranial ependymoma: an integrated molecular and clinical characterization with a long-term follow-up.	Neuro Oncol	2021
33331994	Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases.	Acta Neuropathol	2021
34599019	Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors.	Journal for ImmunoTherapy of Cancer	2021
34373263	The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets.	Cancer Discov	2021
31077608	Tyrosinase immunohistochemistry can be employed for the diagnosis of atypical teratoid/rhabdoid tumours of the tyrosinase subgroup (ATRT-TYR).	Neuropathol Appl Neurobiol	2020
31737984	Genome-wide analysis of acute leukemia and clonally related histiocytic sarcoma in a series of three pediatric patients.	Pediatr Blood Cancer	2020
31732806	Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults.	Acta Neuropathol	2020
31889194	Molecular subgrouping of atypical teratoid/rhabdoid tumors-a reinvestigation and current consensus.	Neuro Oncol	2020
31883020	Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumors.	Neuro Oncol	2020
32341579	Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.	Nat Med	2020
32383815	A single supratentorial high-grade neuroepithelial tumor with two distinct BCOR mutations, exceptionally long complete remission and survival.	Pediatr Blood Cancer	2020
32912900	SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability.	Genes Dev	2020
33109553	Novel Two MRT Cell Lines Established from Multiple Sites of a Synchronous MRT Patient.	Anticancer Research	2020
30887493	Excessive Toxicity After Treatment of Congenital Acute Myeloid Leukemia.	Klinische Padiatrie	2019
31708418	Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration.	Cell Rep	2019
30595504	Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation.	Cancer Cell	2019
30446899	Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors.	J Neurooncol	2019
31419933	RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression.	BMC Bioinformatics	2019
30945057	Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1.	Acta Neuropathol	2019
28218953	Glial papillary tumour of the spinal cord with SMARCB1/INI1-loss and favourable long-term outcome.	Neuropathol Appl Neurobiol	2018
30010851	Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor.	Neuro Oncol	2018
29489754	The landscape of genomic alterations across childhood cancers.	Nature	2018
29351917	A Novel Method for Rapid Molecular Subgrouping of Medulloblastoma.	Clin Cancer Res	2018
29328982	Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS.	J Pharm Biomed Anal	2018