Author details

Full Name

Jorge R Oksenberg

Affiliation

ORCID

Career Start Year

1982

Papers

313

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35253861	Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans.	Brain	2023
37873414	GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.	medRxiv	2023
37205595	A Predictive Autoantibody Signature in Multiple Sclerosis.	medRxiv	2023
37127916	Shared Genetic Risk Factors for Multiple Sclerosis/Psoriasis Suggest Involvement of Interleukin-17 and Janus Kinase-Signal Transducers and Activators of Transcription Signaling.		2023
36997638	Integration of epigenetic and genetic profiles identifies multiple sclerosis disease-critical cell types and genes.	Commun Biol	2023
34878197	Spinal Cord Atrophy Predicts Progressive Disease in Relapsing Multiple Sclerosis.	Ann Neurol	2022
35710320	Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis.	J Neurol Neurosurg Psychiatry	2022
35903875	Epigenetic control of ataxin-1 in multiple sclerosis.	Annals of Clinical and Translational Neurology	2022
36588876	Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.		2022
36548255	Ancestral risk modification for multiple sclerosis susceptibility detected across the Major Histocompatibility Complex in a multi-ethnic population.	PLoS One	2022
35258337	KIR<sup>+</sup>CD8<sup>+</sup> T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.	Science	2022
35233827	Reply to "Spinal Cord Atrophy Is a Preclinical Marker of Progressive MS".	Ann Neurol	2022
35218721	A short HLA-DRA isoform binds the HLA-DR2 heterodimer on the outer domain of the peptide-binding site.	Arch Biochem Biophys	2022
35182500	Multiple sclerosis: two decades of progress.	Lancet Neurology, The	2022
34370753	Genetic susceptibility to multiple sclerosis in African Americans.	PLoS ONE	2021
34177931	Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis.	Front Immunol	2021
34163474	Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations.	Front Immunol	2021
34211458	High Resolution Haplotype Analyses of Classical HLA Genes in Families With Multiple Sclerosis Highlights the Role of HLA-DP Alleles in Disease Susceptibility.	Front Immunol	2021
34025673	High-Resolution Characterization of <i>KIR</i> Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity.	Front Immunol	2021
32986852	A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain.	Immunology	2021
34981055	Human KIR <sup>+</sup> CD8 <sup>+</sup> T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19.	bioRxiv	2021
34911760	Specific hypomethylation programs underpin B cell activation in early multiple sclerosis.	Proc Natl Acad Sci U S A	2021
31368393	The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States.	Mult Scler	2020
33206961	TopoDB: a novel multifunctional management system for laboratory animal colonies.	Database : the journal of biological databases and curation	2020
33046105	Oligodendrocyte-specific Argonaute profiling identifies microRNAs associated with experimental autoimmune encephalomyelitis.	Journal of Neuroinflammation	2020
32709660	Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease.	J Immunol	2020
32878998	Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.	Proc Natl Acad Sci U S A	2020
33037294	Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans.	Sci Rep	2020
32518205	Serum antibodies to phosphatidylcholine in MS.	Neurol Neuroimmunol Neuroinflamm	2020
31407831	Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.	Genet Epidemiol	2019
29915315	Correction: High resolution HLA analysis reveals independent class I haplotypes and amino-acid motifs protective for multiple sclerosis.	Genes Immun	2019
29307888	High resolution HLA analysis reveals independent class I haplotypes and amino-acid motifs protective for multiple sclerosis.	Genes Immun	2019
29683085	Deconstruction of HLA-DRB104:01:01 and HLA-DRB115:01:01 class II haplotypes using next-generation sequencing in European-Americans with multiple sclerosis.	Multiple Sclerosis Journal	2019
31486104	Telomere Length Is Associated with Disability Progression in Multiple Sclerosis.	Ann Neurol	2019
30910980	A specific amino acid motif of <i>HLA-DRB1</i> mediates risk and interacts with smoking history in Parkinson's disease.	Proc Natl Acad Sci U S A	2019
30851128	Silent progression in disease activity-free relapsing multiple sclerosis.	Ann Neurol	2019
31403661	Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years.	JAMA Neurol	2019
31010726	Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation.	J Autoimmun	2019
31345698	Next-generation sequencing reveals new information about HLA allele and haplotype diversity in a large European American population.	Hum Immunol	2019
29273686	Ovarian aging is associated with gray matter volume and disability in women with MS.	Neurology	2018
30175165	Identification of MS-specific serum miRNAs in an international multicenter study.	Neurology: Neuroimmunology and NeuroInflammation	2018
30217166	Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course.	Journal of Neuroinflammation	2018
30480030	Native ancestry is associated with optic neuritis and age of onset in hispanics with multiple sclerosis.	Annals of Clinical and Translational Neurology	2018
29908077	Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis.	Ann Neurol	2018
30321631	Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop.	Hum Immunol	2018
29307290	Multiple sclerosis genetics.	Multiple Sclerosis Journal	2018
29514694	Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients.	Journal of Neuroinflammation	2018
29773642	Correction: Peroxisome proliferator-activated receptor (PPAR)Î± expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.	J Exp Med	2018
27670240	IFN-Î³ orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways.	J Allergy Clin Immunol	2017
28987266	The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years.	Trends Genet	2017