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Author Details

Siavash K Kurdistani
David Geffen School of Medicine, University of California los angeles
1998
62
38
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37889915Metabolic sinkholes: Histones as methyl repositories.PLoS Biol2023
37745536Zinc is Essential for the Copper Reductase Activity of Yeast Nucleosomes.bioRxiv2023
34995510Chromatin as a metabolic organelle: Integrating the cellular flow of carbon with gene expression.Mol Cell2022
35927431Transient nuclear deformation primes epigenetic state and promotes cell reprogramming.Nat Mater2022
32631887The histone H3-H4 tetramer is a copper reductase enzyme.Science2020
30527662Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods.Mol Cell2019
31776511MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment.Nature2019
31558570EvoChromo: towards a synthesis of chromatin biology and evolution.Development2019
30287662Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage.Science2018
27894105Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts.Oncotarget2017
28270516Cbx3 maintains lineage specificity during neural differentiation.Genes Dev2017
29231167Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis.Elife2017
28637866Endoplasmic reticulum-mitochondria junction is required for iron homeostasis.J Biol Chem2017
28735899Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals.Mol Cell2017
27881443Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.Cold Spring Harb Perspect Med2017
26876179MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.Cell Rep2016
26669263EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation.Mol Cell2016
27507714MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis.Nat Commun2016
27226577Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION.J Biol Chem2016
25564442Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence.EMBO J2015
25691465The Ino80 complex prevents invasion of euchromatin into silent chromatin.Genes Dev2015
24172870A unique epigenetic signature is associated with active DNA replication loci in human embryonic stem cells.Epigenetics2014
25525796Adenovirus small E1A employs the lysine acetylases p300/CBP and tumor suppressor Rb to repress select host genes and promote productive virus infection.Cell Host Microbe2014
25016437Chromatin: a capacitor of acetate for integrated regulation of gene expression and cell physiology.Curr Opin Genet Dev2014
24939988Evolution of histone 2A for chromatin compaction in eukaryotes.Elife2014
24639349Histone deacetylase inhibitor sensitizes apoptosis-resistant melanomas to cytotoxic human T lymphocytes through regulation of TRAIL/DR5 pathway.J Immunol2014
24703700Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication.Cell Metab2014
23201122Histone acetylation regulates intracellular pH.Mol Cell2013
23852730CTIP2 is a negative regulator of P-TEFb.Proc Natl Acad Sci U S A2013
23707073EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer.Cell Metab2013
22177115The Rpd3 core complex is a chromatin stabilization module.Curr Biol2012
23177621Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function.Cell Rep2012
22956909Dynamic distribution of linker histone H1.5 in cellular differentiation.PLoS Genet2012
22863011Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium.Cell2012
22910904Polycomb repressive complex 1 (PRC1) disassembles RNA polymerase II preinitiation complexes.J Biol Chem2012
22822071Stimulation of histone deacetylase activity by metabolites of intermediary metabolism.J Biol Chem2012
22499665Reorganization of the host epigenome by a viral oncogene.Genome Res2012
22621675Enhancer dysfunction: how the main regulators of gene expression contribute to cancer.Genome Biol2012
21141726Histone modifications in cancer biology and prognosis.Prog Drug Res2011
22073215Genome-wide binding map of the HIV-1 Tat protein to the human genome.PLoS One2011
20142597Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704.J Clin Oncol2010
19211936Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis.Blood2009
19349354Global levels of histone modifications predict prognosis in different cancers.Am J Pathol2009
19290008Viral manipulation of the host epigenome for oncogenic transformation.Nat Rev Genet2009
18493053Regulators of cellular levels of histone acetylation in Saccharomyces cerevisiae.Genetics2008
18719284Epigenetic reprogramming by adenovirus e1a.Science2008
18719283Adenovirus small e1a alters global patterns of histone modification.Science2008
17592497Histone modifications as markers of cancer prognosis: a cellular view.Br J Cancer2007
18091724Modeling the regulatory network of histone acetylation in Saccharomyces cerevisiae.Mol Syst Biol2007
15988529Global histone modification patterns predict risk of prostate cancer recurrence.Nature2005
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Collaborators

Michael Grunstein
University of California los angeles
Co-authored papers 12
Matteo Pellegrini
Co-authored papers 9
Ajay A Vashisht
David Geffen School of Medicine, University of California los angeles
Co-authored papers 5
James A Wohlschlegel
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 5
Heather R Christofk
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 5
Steve Horvath
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
Stuart H Orkin
Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 3
Rajkumar Sasidharan
University of California los angeles
Co-authored papers 3
Craig L Peterson
Co-authored papers 2
Linda Yen
Middlemore Hospital
Co-authored papers 2
Nicholas A Graham
University of Southern California
Co-authored papers 2
Aldons J Lusis
Co-authored papers 2
Stanley F Nelson
university of california los angeles
Co-authored papers 2
Lee Goodglick
Co-authored papers 2
Sean R Collins
University of California davis
Co-authored papers 1
Steven M Dubinett
David Geffen School of Medicine at university of california los angeles
Co-authored papers 1
Lukasz Salwinski
university of california los angeles
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Charles Boone
University of Toronto
Co-authored papers 1
Jennifer Soto
Mayo Clinic
Co-authored papers 1
Jau-Nian Chen
University of California los angeles
Co-authored papers 1
Song Li
Co-authored papers 1
Laurent Vergnes
Co-authored papers 1
Qin Peng
Co-authored papers 1
Karen Reue
Co-authored papers 1
Owen N Witte
University of California los angeles
Co-authored papers 1
Peter Refsing Andersen
Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
Co-authored papers 1
Elaheh Karbassi
Co-authored papers 1
Harmit S Malik
Fred Hutchinson Cancer Center
Co-authored papers 1
Andrew Emili
Boston University School of Medicine, Boston University
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Release 1.2