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Author Details

Alessandro Ori
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
2007
82
35
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36747793Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.bioRxiv2023
37630850Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice.Nutrients2023
37318382Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology.J Cell Biol2023
37101405Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.Aging Cell2023
34695195PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.Blood2022
35767948Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction.Cell Rep2022
35594347Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration.Sci Adv2022
35513564The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2.Oncogene2022
36179048Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.Proc Natl Acad Sci U S A2022
36131016CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.Nature2022
35053391Multifaceted Microcephaly-Related Gene MCPH1.Cells2022
35194998Glycation Alters the Fatty Acid Binding Capacity of Human Serum Albumin.J Agric Food Chem2022
35165416Metabolic determination of cell fate through selective inheritance of mitochondria.Nat Cell Biol2022
34368155The Hematopoietic Bone Marrow Niche Ecosystem.Front Cell Dev Biol2021
33542216The N-terminal BRCT domain determines MCPH1 function in brain development and fertility.Cell Death Dis2021
33594975HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.Elife2021
33755596GMPPA defects cause a neuromuscular disorder with α-dystroglycan hyperglycosylation.J Clin Invest2021
33855766Aging drives organ-specific alterations of the inflammatory microenvironment guided by immunomodulatory mediators in mice.FASEB J2021
34516047Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses.Curr Protoc2021
34683917Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice.Pharmaceutics2021
34795246Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.Nat Commun2021
34107247Extensive remodeling of the extracellular matrix during aging contributes to age-dependent impairments of muscle stem cell functionality.Cell Rep2021
34210973ATR regulates neuronal activity by modulating presynaptic firing.Nat Commun2021
32558274Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation.Mol Syst Biol2020
31795790The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan.Autophagy2020
33139960Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans.Nat Metab2020
32807790Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.Nat Commun2020
32574648Stem cell aging: The upcoming era of proteins and metabolites.Mech Ageing Dev2020
32737464Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.Nat Protoc2020
32348758Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction.Cell Rep2020
30530755Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.J Exp Med2019
31817246Increased Expression of Immature Mannose-Containing Glycoproteins and Sialic Acid in Aged Mouse Brains.Int J Mol Sci2019
31783876Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer.Cell Commun Signal2019
31719688Author Correction: Metastatic-niche labelling reveals parenchymal cells with stem features.Nature2019
31733513Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines.iScience2019
31503451Quantitation of Reactive Acyl-CoA Species Mediated Protein Acylation by HPLC-MS/MS.Anal Chem2019
31462798Metastatic-niche labelling reveals parenchymal cells with stem features.Nature2019
30886199Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p.Sci Rep2019
31089132Nucleoporin Nup155 is part of the p53 network in liver cancer.Nat Commun2019
31031010Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals.Cell2019
30726097Comparison of Protein Quantification in a Complex Background by DIA and TMT Workflows with Fixed Instrument Time.J Proteome Res2019
29700228NUFIP1 is a ribosome receptor for starvation-induced ribophagy.Science2018
30082728TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.Nat Commun2018
29967062Quantifying compartment-associated variations of protein abundance in proteomics data.Mol Syst Biol2018
29858605Cellular and epigenetic drivers of stem cell ageing.Nat Rev Mol Cell Biol2018
30209298Author Correction: TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells.Nat Commun2018
30068331Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.BMC Biol2018
29363612Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC).Mol Cell Proteomics2018
27939741Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.Am J Pathol2017
29254951Landscape of nuclear transport receptor cargo specificity.Mol Syst Biol2017
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Collaborators

Max Planck Institute of Biophysics
Co-authored papers 26
University of Wurzburg
Co-authored papers 10
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 7
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 7
Friedrich Miescher Institute for Biomedical Research
Co-authored papers 6
Interdisciplinary Research Center HALOmem, Martin Luther University Halle-Wittenberg
Co-authored papers 4
Co-authored papers 4
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 4
University of Basel
Co-authored papers 3
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Co-authored papers 3
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
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Institut Curie, PSL Research University, Sorbonne Universite, CNRS
Co-authored papers 1
German Cancer Research Center (DKFZ)
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 1
Institute of Pathology, Heidelberg University Hospital
Co-authored papers 1
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
University of Munich
Co-authored papers 1
ETH Zurich
Co-authored papers 1
Heidelberg University Hospital
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Harvard Medical School
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Leiden University, Institute of Biology Leiden
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Karolinska Institutet
Co-authored papers 1