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Author Details

Yang Chen
The University of Texas MD Anderson Cancer Center
2008
59
35
PMIDPaper TitleJournal TitlePublished Year
36945457Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer.bioRxiv2023
37625403Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8<sup>+</sup> T cells.Dev Cell2023
37998349Single-Cell Analysis Differentiates the Effects of p53 Mutation and p53 Loss on Cell Compositions of Oncogenic Kras-Driven Pancreatic Cancer.Cells2023
37778962Anxiolytics cause anxiety in pancreatic cancer.Trends Cancer2023
37190324Cross-Dataset Single-Cell Analysis Identifies Temporal Alterations in Cell Populations of Primary Pancreatic Tumor and Liver Metastasis.Cancers (Basel)2023
36008138KLF5 governs sphingolipid metabolism and barrier function of the skin.Genes Dev2022
35348629Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.Cancer Discov2022
35868307Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer.Cancer Cell2022
32732355Hematopoietic recovery and immune reconstitution after axicabtagene ciloleucel in patients with large B-cell lymphoma.Haematologica2021
33667385Type I collagen deletion in αSMA<sup>+</sup> myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer.Cancer Cell2021
33855751Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis.FASEB J2021
34893625Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta.Nat Commun2021
34489603Clinical and therapeutic relevance of cancer-associated fibroblasts.Nat Rev Clin Oncol2021
34717064MiR-18a Inhibits PI3K/AKT Signaling Pathway to Regulate PDGF BB-Induced Airway Smooth Muscle Cell Proliferation and Phenotypic Transformation.Physiol Res2021
32771052Mesenchymal stromal cell therapies: immunomodulatory properties and clinical progress.Stem Cell Res Ther2020
31888886Wnt-Induced Stabilization of KDM4C Is Required for Wnt/β-Catenin Target Gene Expression and Glioblastoma Tumorigenesis.Cancer Res2020
33321084Stromal Cells Exhibit Prevalent Genetic Aberrations in Colorectal Cancer.Cancer Cell2020
31205619Application of PD-1 Blockade in Cancer Immunotherapy.Comput Struct Biotechnol J2019
30592710Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis.PLoS Biol2018
30120146Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.EMBO Mol Med2018
29430029On pseudolikelihood inference for semiparametric models with boundary problems.Biometrika2017
28334132Maximum likelihood estimation and EM algorithm of Copas-like selection model for publication bias correction.Biostatistics2017
28344040m<sup>6</sup>A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.Cancer Cell2017
26822154The Dual MEK/FLT3 Inhibitor E6201 Exerts Cytotoxic Activity against Acute Myeloid Leukemia Cells Harboring Resistance-Conferring FLT3 Mutations.Cancer Res2016
27758883Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation.Cancer Res2016
27501329Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.Nat Cell Biol2016
27448187Prognostic significance of baseline peripheral absolute neutrophil, monocyte and serum β2-microglobulin level in patients with diffuse large b-cell lymphoma: a new prognostic model.Br J Haematol2016
26912724Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation.EMBO J2016
26956049Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network.Oncotarget2016
25048874Myeloid neoplasms after breast cancer: "therapy-related" not an independent poor prognostic factor.Leuk Lymphoma2015
31051696Epithelioid hemangioendothelioma: a study of 14 cytopathology cases.J Am Soc Cytopathol2015
25639486Tumour suppressor TRIM33 targets nuclear β-catenin degradation.Nat Commun2015
24154679Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth.Ann Hematol2014
25228589Clinical outcomes of a novel combination of lenalidomide and rituximab followed by stem cell transplantation for relapsed/refractory aggressive B-cell non-hodgkin lymphoma.Oncotarget2014
24974852Current regimens and novel agents for mantle cell lymphoma.Br J Haematol2014
24886772Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study.J Hematol Oncol2014
24599548Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance.Blood2014
24619500Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies.Clin Cancer Res2014
24316223PKM2 regulates chromosome segregation and mitosis progression of tumor cells.Mol Cell2014
23101590Splenic marginal zone lymphoma: a population-based study on the 2001-2008 incidence and survival in the United States.Leuk Lymphoma2013
23676502CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia.J Clin Invest2013
23741006Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment.Blood2013
23484027The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo.PLoS One2013
23545991Oral lenalidomide with rituximab in relapsed or refractory diffuse large cell, follicular and transformed lymphoma: a phase II clinical trial.Leukemia2013
23316859Lenalidomide as a novel treatment of acute myeloid leukemia.Expert Opin Investig Drugs2013
23121646Trends in chronic myeloid leukemia incidence and survival in the United States from 1975 to 2009.Leuk Lymphoma2013
23135353Prognostic significance of 11q23 aberrations in adult acute myeloid leukemia and the role of allogeneic stem cell transplantation.Leukemia2013
22139816Temporal and geographic variations of Waldenstrom macroglobulinemia incidence: a large population-based study.Cancer2012
22707337Acute promyelocytic leukemia: a population-based study on incidence and survival in the United States, 1975-2008.Cancer2012
22490334Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment.Blood2012
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Collaborators

Jorge Cortes
Georgia Cancer Center
Co-authored papers 7
Hagop Kantarjian
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Farhad Ravandi
University of Texas M.D. Anderson Cancer Center
Co-authored papers 6
Aidong Zhou
Southern Medical University
Co-authored papers 5
Suyun Huang
Virginia Commonwealth University
Co-authored papers 5
Sicong Zhang
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
Gautam Borthakur
MD Anderson Cancer Center
Co-authored papers 5
Bingrui Li
Metastasis Research Center, University of Texas MD Anderson Cancer Center
Co-authored papers 4
Mien-Chie Hung
Co-authored papers 4
Qingyi Wei
South China University of Technology
Co-authored papers 4
Kangyu Lin
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Guillermo Garcia-Manero
MD Anderson Cancer Center
Co-authored papers 3
Wei Zhang
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Dirk Strunk
Cell Therapy Institute, Paracelsus Medical University (PMU)
Co-authored papers 3
Kenneth Aldape
National Cancer Institute
Co-authored papers 3
Sadhan Majumder
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Steven M Kornblau
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Keping Xie
The South China University of Technology Comprehensive Cancer Center
Co-authored papers 2
Anirban Maitra
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Jianhua Zhang
University of Texas MD Anderson Cancer Center
Co-authored papers 1
Fuu-Jen Tsai
Co-authored papers 1
Siyuan Zheng
Greehey Children's Cancer Research Institute
Co-authored papers 1
Naoki Shinojima
Kumamoto University Hospital
Co-authored papers 1
Chuan He
Institute of Hematology, West China Hospital of Sichuan University
Co-authored papers 1
Boxuan Simen Zhao
The University of Chicago
Co-authored papers 1
Gregory N Fuller
MD Anderson Cancer Center
Co-authored papers 1
Jun Qin
Co-authored papers 1
Oliver B??gler
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Richard B Lock
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
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Katharina Schallmoser
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Release 1.2