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Author Details

Will Dampier
Drexel University College of Medicine
2007
48
18
PMIDPaper TitleJournal TitlePublished Year
36672628Immunomodulatory Effects of Non-Thermal Plasma in a Model for Latent HIV-1 Infection: Implications for an HIV-1-Specific Immunotherapy.Biomedicines2023
37124096Assessment of anti-HIV-1 guide RNA efficacy in cells containing the viral target sequence, corresponding gRNA, and CRISPR/Cas9.Front Genome Ed2023
36090285Examining virtual driving test performance and its relationship to individuals with HIV-associated neurocognitive disorders.Front Neurosci2022
33331178HIV-1 cure strategies: why CRISPR?Expert Opin Biol Ther2021
33768011Computational Design of gRNAs Targeting Genetic Variants Across HIV-1 Subtypes for CRISPR-Mediated Antiviral Therapy.Front Cell Infect Microbiol2021
33647028Non-thermal plasma modulates cellular markers associated with immunogenicity in a model of latent HIV-1 infection.PLoS One2021
34713260Off-Target Analysis in Gene Editing and Applications for Clinical Translation of CRISPR/Cas9 in HIV-1 Therapy.Front Genome Ed2021
32265877HIV-1 Tat Length: Comparative and Functional Considerations.Front Microbiol2020
31672284Computational Analysis Concerning the Impact of DNA Accessibility on CRISPR-Cas9 Cleavage Efficiency.Mol Ther2020
32818921Safe CRISPR-Cas9 Inhibition of HIV-1 with High Specificity and Broad-Spectrum Activity by Targeting LTR NF-κB Binding Sites.Mol Ther Nucleic Acids2020
32903440Designing Safer CRISPR/Cas9 Therapeutics for HIV: Defining Factors That Regulate and Technologies Used to Detect Off-Target Editing.Front Microbiol2020
32354973Integrated Human Immunodeficiency Virus Type 1 Sequence in J-Lat 10.6.Microbiol Resour Announc2020
31437485Investigating the distribution of HIV-1 Tat lengths present in the Drexel Medicine CARES cohort.Virus Res2019
31745112Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients.Sci Rep2019
30619107Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection.Front Microbiol2018
30022098GOATOOLS: A Python library for Gene Ontology analyses.Sci Rep2018
29968495Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics.AIDS Res Hum Retroviruses2018
31021222Prediction of Human Immunodeficiency Virus Type 1 Subtype-Specific Off-Target Effects Arising from CRISPR-Cas9 Gene Editing Therapy.CRISPR J2018
27400931Specific amino acids in HIV-1 Vpr are significantly associated with differences in patient neurocognitive status.J Neurovirol2017
28290581Deconvolution of heterogeneous wound tissue samples into relative macrophage phenotype composition via models based on gene expression.Integr Biol (Camb)2017
28318799Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing.Immunobiology2017
29225709Immunomodulatory Effects of Human Cryopreserved Viable Amniotic Membrane in a Pro-Inflammatory Environment <i>In Vitro</i>.Cell Mol Bioeng2017
29089503Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants.Sci Rep2017
28620613Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences.Int J Genomics2017
27100290HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease Severity.PLoS One2016
27711166Mitochondrial Haplogroup Influences Motor Function in Long-Term HIV-1-Infected Individuals.PLoS One2016
27195985HIV-1 Genetic Variation Resulting in the Development of New Quasispecies Continues to Be Encountered in the Peripheral Blood of Well-Suppressed Patients.PLoS One2016
27143130Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures.Retrovirology2016
27294916Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain Barrier.Int J Mol Sci2016
27009094HIV-1 Latency and Eradication: Past, Present and Future.Curr HIV Res2016
25940700Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis.Oncotarget2015
24551078CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage.PLoS One2014
25893217HIV Excision Utilizing CRISPR/Cas9 Technology: Attacking the Proviral Quasispecies in Reservoirs to Achieve a Cure.MOJ Immunol2014
25265194Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences.PLoS One2014
24732878Cocaine alters cytokine profiles in HIV-1-infected African American individuals in the DrexelMed HIV/AIDS genetic analysis cohort.J Acquir Immune Defic Syndr2014
24862329Bioinformatic analysis of HIV-1 entry and pathogenesis.Curr HIV Res2014
22432004Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis.PLoS One2012
22488912Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases.Inflamm Bowel Dis2012
22307325ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice.J Clin Invest2012
21165954Large-scale integration of microarray data reveals genes and pathways common to multiple cancer types.Int J Cancer2011
21858059HIV protein sequence hotspots for crosstalk with host hub proteins.PLoS One2011
21738584Sequence- and interactome-based prediction of viral protein hotspots targeting host proteins: a case study for HIV Nef.PLoS One2011
20351289Attenuation of Forkhead signaling by the retinal determination factor DACH1.Proc Natl Acad Sci U S A2010
19450270Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs.BMC Med Genomics2009
19627600Host sequence motifs shared by HIV predict response to antiretroviral therapy.BMC Med Genomics2009
18521530Collagen's triglycine repeat number and phylogeny suggest an interdomain transfer event from a Devonian or Silurian organism into Trichodesmium erythraeum.J Mol Evol2008
17559886Signaling perturbations induced by invading H. pylori proteins in the host epithelial cells: a mathematical modeling approach.J Theor Biol2007
17963508Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets.BMC Bioinformatics2007
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Collaborators

Co-authored papers 12
College of Medicine, Drexel University
Co-authored papers 6
Co-authored papers 4
Co-authored papers 3
College of Medicine, University of Florida.
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Temple University
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University of Pennsylvania
Co-authored papers 2
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College of Agriculture and Biotechnology, Zhejiang University
Co-authored papers 1
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Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
GlaxoSmithKline Pharma R&D, 1250 S. Collegeville Rd, Collegeville
Co-authored papers 1
University of Lausanne
Co-authored papers 1
Co-authored papers 1
Drexel University
Co-authored papers 1
Co-authored papers 1
Max Planck Institute of Immunobiology and Epigenetics
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Center for Molecular Medicine, University Medical Center Utrecht
Co-authored papers 1
Center for Genomics and Biotechnology, Fujian Agriculture and Forestry University
Co-authored papers 1
Washington University School of Medicine
Co-authored papers 1
International Society for Biocuration, Lawrence Berkeley National Laboratory, University of Edinburgh, University of Edinburgh School of Biological Sciences
Co-authored papers 1
Institut de Biologie de l'Ecole Normale Superieure, Inserm, CNRS, Universite PSL
Co-authored papers 1
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 1
University of Lausanne
Co-authored papers 1
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Georgia Institute of Technology
Co-authored papers 1
University of California san francisco
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