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Author Details
Full Name
Richard J Bram
Affiliation
Mayo Clinic College of Medicine
ORCID
Career Start Year
1980
Papers
78
H Index
34
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36248275
Accelerated Aging in Cyclophilin B-Deficient Mice Downstream of p21-Cip1/Waf1.
JBMR Plus
2022
35767640
Early expression of mature αβ TCR in CD4<sup>-</sup>CD8<sup>-</sup> T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations.
Proc Natl Acad Sci U S A
2022
35821679
Phase I trial of sargramostim/pelareorep therapy in pediatric patients with recurrent or refractory high-grade brain tumors.
Neurooncol Adv
2022
34111031
TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA.
JCI Insight
2021
34283811
TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells.
JCI Insight
2021
32162654
Cyclophilins A and B oppositely regulate renal tubular epithelial cell phenotype.
J Mol Cell Biol
2020
30716352
Immunotherapy in pediatric B-cell acute lymphoblastic leukemia.
Hum Immunol
2019
31661505
Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL.
PLoS One
2019
27779616
Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy.
Gene Ther
2017
28490517
ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.
Cancer Res
2017
29085850
Protein synthesis inhibition enhances paraptotic death induced by inhibition of cyclophilins in glioblastoma cells.
Cancer Cell Microenviron
2017
28749467
Yet another hump for CAML: support of cell survival independent of tail-anchored protein insertion.
Cell Death Dis
2017
28580168
CAML mediates survival of Myc-induced lymphoma cells independent of tail-anchored protein insertion.
Cell Death Discov
2017
28518150
Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme.
Cell Death Dis
2017
27609654
Heterozygosity for transmembrane activator and calcium modulator ligand interactor A144E causes haploinsufficiency and pneumococcal susceptibility in mice.
J Allergy Clin Immunol
2017
27226539
Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.
J Biol Chem
2016
27591255
Tail-anchored protein insertion in mammals. FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR.
J Biol Chem
2016
25962322
BAFF receptor and TACI in B-1b cell maintenance and antibacterial responses.
Ann N Y Acad Sci
2015
26561552
Calcium-Modulating Cyclophilin Ligand Is Essential for the Survival of Activated T Cells and for Adaptive Immunity.
J Immunol
2015
24218480
Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI.
Infect Immun
2014
25271628
TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen.
J Clin Invest
2014
24755487
A novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death.
Cancer Biol Ther
2014
24647692
Anasarca, hypoalbuminemia, and anemia: what is the correlation?
Clin Pediatr (Phila)
2014
24646744
Impaired B cell receptor signaling is responsible for reduced TACI expression and function in X-linked immunodeficient mice.
J Immunol
2014
24272483
Cyclophilin B supports Myc and mutant p53-dependent survival of glioblastoma multiforme cells.
Cancer Res
2014
23134680
The anticancer drug Dp44mT inhibits T-cell activation and CD25 through a copper-dependent mechanism.
FASEB J
2013
23322463
BAFF expression correlates with idiopathic inflammatory myopathy disease activity measures and autoantibodies.
J Rheumatol
2013
22170629
Conditional deletion of calcium-modulating cyclophilin ligand causes deafness in mice.
Mamm Genome
2012
25192139
Protons: moving therapy for hodgkin lymphoma in a positive direction.
Oncology (Williston Park)
2012
23144461
Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat).
J Biol Chem
2012
23080194
TBK1 suppression of IgA in the NIK of time.
Nat Immunol
2012
22291190
Cutting edge: regulation of TLR4-driven B cell proliferation by RP105 is not B cell autonomous.
J Immunol
2012
22351938
Essential role for CAML in follicular B cell survival and homeostasis.
J Immunol
2012
21306646
Enhanced immunogenicity of pneumococcal surface adhesin A (PsaA) in mice via fusion to recombinant human B lymphocyte stimulator (BLyS).
Biol Direct
2011
21984806
TACI deficiency impairs sustained Blimp-1 expression in B cells decreasing long-lived plasma cells in the bone marrow.
Blood
2011
21881204
Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI.
J Clin Invest
2011
20300112
CAML regulates Bim-dependent thymocyte death.
Cell Death Differ
2010
20889194
The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency.
J Allergy Clin Immunol
2010
20516639
HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in mice.
J Clin Invest
2010
19229138
CAML loss causes anaphase failure and chromosome missegregation.
Cell Cycle
2009
19997487
Severe osteogenesis imperfecta in cyclophilin B-deficient mice.
PLoS Genet
2009
19605846
The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function.
Blood
2009
19427685
Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells.
J Allergy Clin Immunol
2009
18424167
Calcium-modulating cyclophilin ligand regulates membrane trafficking of postsynaptic GABA(A) receptors.
Mol Cell Neurosci
2008
18500349
Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu.
Nat Med
2008
18606649
Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL.
J Immunol
2008
16968890
Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease.
Am J Physiol Renal Physiol
2007
17548587
TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells.
J Immunol
2007
17675489
TACI is required for efficient plasma cell differentiation in response to T-independent type 2 antigens.
J Immunol
2007
16357320
Selective activation of TACI by syndecan-2.
Blood
2006
1 - 50 of 78
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Collaborators
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Stanford University
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Kameswaran Surendran
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Peter L Freddolino
University of Michigan ann arbor
Co-authored papers
1
Hasitha Premathilake
Oklahoma State University
Co-authored papers
1
Anton A Komar
Center for Gene Regulation in Health and Disease, Cleveland State University
Co-authored papers
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Katie B Grausam
Board of Governor's Regenerative Medicine Institute, Cedars-Sinai Medical Center .
Co-authored papers
1
Samuel D R Dooyema
Vanderbilt University Medical Center
Co-authored papers
1
Antoine Forget (CM4AI)
University of California San Francisco
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Erliang Zeng
College of Dentistry, University of Iowa
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1
Xijin Ge
South Dakota State University
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1
Indra Chandrasekar
University of South Dakota Sanford School of Medicine
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Alex H Heglin
University of South Dakota
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1
Emily C Baechler
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Jeremy J Rose
National Cancer Institute
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Anca Sorana Morrissy
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