Author details

Full Name

Jon H Tobias

Affiliation

ORCID

Career Start Year

1989

Papers

259

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37096546	Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization.	Arthritis Rheumatol	2023
37935324	Comparison between UK Biobank and Shanghai Changfeng suggests distinct hip morphology may contribute to ethnic differences in the prevalence of hip osteoarthritis.		2023
37704099	Hip geometric parameters are associated with radiographic and clinical hip osteoarthritis: Findings from a cross-sectional study in UK Biobank.		2023
37619450	The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses.	EBioMedicine	2023
37402774	Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis.	Commun Biol	2023
37023531	B4GALNT3 regulates glycosylation of sclerostin and bone mass.	EBioMedicine	2023
36824040	Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism.		2023
37133737	Age-specific effects of weight-based body size on fracture risk in later life: a lifecourse Mendelian randomisation study.	Eur J Epidemiol	2023
36662418	A Genome-Wide Association Study Meta-Analysis of Alpha Angle Suggests Cam-Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults.	Arthritis Rheumatol	2023
37490188	Sclerostin and Cardiovascular Disease.		2023
35284926	A clinical tool to identify older women with back pain at high risk of osteoporotic vertebral fractures (Vfrac): a population-based cohort study with exploratory economic evaluation.	Age and Ageing	2022
35957823	Editorial: Insights in bone research 2021.	Frontiers in Endocrinology	2022
35577538	Strong, steady and straight: UK consensus statement on physical activity and exercise for osteoporosis.	British Journal of Sports Medicine	2022
35880304	Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank.	J Bone Miner Res	2022
35811326	Machine Learning-Derived Acetabular Dysplasia and Cam Morphology Are Features of Severe Hip Osteoarthritis: Findings From UK Biobank.	Journal of Bone and Mineral Research	2022
35933372	High bone mass and cam morphology are independently related to hip osteoarthritis: findings from the High Bone Mass cohort.	BMC Musculoskelet Disord	2022
36501877	Machine Learning Models for Weight-Bearing Activity Type Recognition Based on Accelerometry in Postmenopausal Women.		2022
36619575	Editorial: The "GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork" (GEMSTONE).		2022
34870723	Role of the Microbiome in Regulating Bone Metabolism and Susceptibility to Osteoporosis.	Calcif Tissue Int	2022
34919677	A novel semi-automated classifier of hip osteoarthritis on DXA images shows expected relationships with clinical outcomes in UK Biobank.	Rheumatology (Oxford)	2022
34738659	Circulating Sclerostin Levels Are Positively Related to Coronary Artery Disease Severity and Related Risk Factors.	J Bone Miner Res	2022
35212826	Assessment of Activity Profiles in Older Adults and Lower Limb Bone Parameters: Observations from the Hertfordshire Cohort Study.	Calcified Tissue International	2022
34897459	Using multivariable Mendelian randomization to estimate the causal effect of bone mineral density on osteoarthritis risk, independently of body mass index.	Int J Epidemiol	2022
34542150	GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating Î±-Klotho levels.	Hum Mol Genet	2022
34419604	Cam morphology but neither acetabular dysplasia nor pincer morphology is associated with osteophytosis throughout the hip: findings from a cross-sectional study in UK Biobank.	Osteoarthritis Cartilage	2021
33538965	Osteoarthritis: Insights Offered by the Study of Bone Mass Genetics.	Curr Osteoporos Rep	2021
33776944	Editorial: Recent Advances in the Genetics of Osteoporosis.	Frontiers in Endocrinology	2021
33658983	Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy of the Royal Osteoporosis Society on October 5th 2020.	Front Endocrinol (Lausanne)	2021
34131654	Anabolic treatments for osteoporosis in postmenopausal women.		2021
33027520	Mendelian randomization provides evidence for a causal effect of higher serum IGF-1 concentration on risk of hip and knee osteoarthritis.	Rheumatology (Oxford)	2021
33285254	The influence of adult hip shape genetic variants on adolescent hip shape: Findings from a population-based DXA study.	Bone	2021
32781434	Investigation of the Relationship Between Peak Vertical Accelerations and Aerobic Exercise Intensity During Graded Walking and Running in Postmenopausal Women.	Journal of Aging and Physical Activity	2021
33407835	Increased development of radiographic hip osteoarthritis in individuals with high bone mass: a prospective cohort study.	Arthritis Res Ther	2021
34389713	RSPO3 is important for trabecular bone and fracture risk in mice and humans.	Nat Commun	2021
34389476	Osteophyte size and location on hip DXA scans are associated with hip pain: Findings from a cross sectional study in UK Biobank.	Bone	2021
31525280	A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD-Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis.	J Bone Miner Res	2020
32380867	Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts.	Ann Hum Biol	2020
31794847	The effect of pubertal timing, as reflected by height tempo, on proximal femur shape: Findings from a population-based study in adolescents.		2020
31693244	Response to: Effects of Alendronic Acid on Fracture Healing.	Journal of Bone and Mineral Research	2020
31644466	Unpicking observational relationships between hip shape and osteoarthritis: hype or hope?	Current Opinion in Rheumatology	2020
32417557	Individuals with high bone mass have increased progression of radiographic and clinical features of knee osteoarthritis.	Osteoarthritis Cartilage	2020
32176830	Characteristics of Early Paget's Disease in SQSTM1 Mutation Carriers: Baseline Analysis of the ZiPP Study Cohort.	Journal of Bone and Mineral Research	2020
32165724	Sex differences in proximal femur shape: findings from a population-based study in adolescents.	Scientific Reports	2020
32163637	The Effect of Plasma Lipids and Lipid-Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study.	J Bone Miner Res	2020
31667854	Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population.	Clin Endocrinol (Oxf)	2020
32387760	Subregional statistical shape modelling identifies lesser trochanter size as a possible risk factor for radiographic hip osteoarthritis, a cross-sectional analysis from the Osteoporotic Fractures in Men Study.	Osteoarthritis Cartilage	2020
32031638	Capturing remote disease activity - results of a 12-month clinical pilot of a smartphone app in NHS rheumatology clinics in Bristol.	Rheumatology	2020
32877967	Associations between prenatal indicators of mechanical loading and proximal femur shape: findings from a population-based study in ALSPAC offspring.	J Musculoskelet Neuronal Interact	2020
32804215	Physical Activity Throughout Adolescence and Peak Hip Strength in Young Adults.	JAMA Netw Open	2020
32514764	Correction to: Lean mass and lower limb muscle function in relation to hip strength, geometry and fracture risk indices in community-dwelling older women.	Osteoporos Int	2020