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Author Details
Full Name
Leslie Cope
Affiliation
Johns Hopkins University School of Medicine
ORCID
Career Start Year
2003
Papers
129
H Index
50
Expertise
CM4AI Collaborator
Prashant Mali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36534524
Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial.
Clin Cancer Res
2023
37218167
Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use.
Epigenetics
2023
37039321
Multiplex Digital Methylation-Specific PCR for Noninvasive Screening of Lung Cancer.
Adv Sci (Weinh)
2023
36919699
HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation.
J Clin Invest
2023
36811956
Increasing the Capture Rate of Circulating Tumor DNA in Unaltered Plasma Using Passive Microfluidic Mixer Flow Cells.
Langmuir
2023
34492116
A semiparametric isotonic regression model for skewed distributions with application to DNA-RNA-protein analysis.
Biometrics
2022
36463226
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence.
Clin Epigenetics
2022
36046124
Development of an automated liquid biopsy assay for methylated markers in advanced breast cancer.
Cancer Res Commun
2022
36206311
Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis.
Cancer Res
2022
33666134
DNA-methylation for the detection and distinction of 19 human malignancies.
Epigenetics
2022
34021745
Jutils: a visualization toolkit for differential alternative splicing events.
Bioinformatics
2021
33520697
HEYL Regulates Neoangiogenesis Through Overexpression in Both Breast Tumor Epithelium and Endothelium.
Front Oncol
2021
33491650
Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer.
Elife
2021
34907910
Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers.
J Clin Invest
2021
34396532
Mutation and methylation profiles of ectopic and eutopic endometrial tissues.
J Pathol
2021
34341513
CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer.
Oncogene
2021
34234148
Automated and rapid detection of cancer in suspicious axillary lymph nodes in patients with breast cancer.
NPJ Breast Cancer
2021
33952317
Methylated markers accurately distinguish primary central nervous system lymphomas (PCNSL) from other CNS tumors.
Clin Epigenetics
2021
34001907
Running the full human developmental clock in interspecies chimeras using alternative human stem cells with expanded embryonic potential.
NPJ Regen Med
2021
34165589
Retrospective analysis of cancer-specific gene expression panel for thyroid fine needle aspiration specimens.
J Cancer Res Clin Oncol
2021
34112666
Analysis of multispectral imaging with the AstroPath platform informs efficacy of PD-1 blockade.
Science
2021
31531802
High mobility group A1 (HMGA1) protein and gene expression correlate with ER-negativity and poor outcomes in breast cancer.
Breast Cancer Res Treat
2020
32025567
DNA methylation markers predict recurrence-free interval in triple-negative breast cancer.
NPJ Breast Cancer
2020
32992569
Integrated Multiparametric Radiomics and Informatics System for Characterizing Breast Tumor Characteristics with the OncotypeDX Gene Assay.
Cancers (Basel)
2020
32349388
Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla-Site of Origin of Serous Carcinoma of the Ovary.
Cancers (Basel)
2020
30789293
Measuring DNA Copy Number Variation Using High-Density Methylation Microarrays.
J Comput Biol
2019
31300453
DNA Methylation Markers for Breast Cancer Detection in the Developing World.
Clin Cancer Res
2019
31611308
Functional Loss of <i>ATRX</i> and <i>TERC</i> Activates Alternative Lengthening of Telomeres (ALT) in LAPC4 Prostate Cancer Cells.
Mol Cancer Res
2019
31373686
Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types.
Int J Cancer
2019
31343420
Clinicopathologic and Molecular Features of Paired Cases of Metachronous Ovarian Serous Borderline Tumor and Subsequent Serous Carcinoma.
Am J Surg Pathol
2019
30841906
Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.
J Immunother Cancer
2019
30744692
Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1.
J Immunother Cancer
2019
30863929
DNA methylation genome-wide analysis in remnant and primary gastric cancers.
Gastric Cancer
2019
29600241
A Standardized Needs Assessment Tool to Inform the Curriculum Development Process for Pediatric Resuscitation Simulation-Based Education in Resource-Limited Settings.
Front Pediatr
2018
30225619
Young age at diagnosis is associated with worse prognosis in the Luminal A breast cancer subtype: a retrospective institutional cohort study.
Breast Cancer Res Treat
2018
29895573
The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity.
Cancer Immunol Res
2018
30108103
Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions.
Clin Cancer Res
2018
30486871
Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer.
Breast Cancer Res
2018
29383066
Do End-of-Rotation and End-of-Shift Assessments Inform Clinical Competency Committees' (CCC) Decisions?
West J Emerg Med
2018
27870562
Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study.
J Clin Oncol
2017
28388418
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.
Cell
2017
28193624
Transcriptional Mechanisms of Resistance to Anti-PD-1 Therapy.
Clin Cancer Res
2017
28452345
HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.
Nat Commun
2017
29042553
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma.
Nat Commun
2017
28596308
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
Science
2017
27979916
Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study.
Clin Cancer Res
2017
27637888
Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer.
Clin Cancer Res
2017
27001612
The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Gynecol Oncol
2016
27982207
Comparison of 20% sulfur hexafluoride with air for intraocular tamponade in Descemet membrane endothelial keratoplasty (DMEK).
Arq Bras Oftalmol
2016
27696867
Fecal Metabolome in Hmga1 Transgenic Mice with Polyposis: Evidence for Potential Screen for Early Detection of Precursor Lesions in Colorectal Cancer.
J Proteome Res
2016
1 - 50 of 129
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Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
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Maastricht University Medical Center
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Johns Hopkins University School of Medicine
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Victor E Velculescu
Co-authored papers
6
Vered Stearns
Co-authored papers
6
Timothy A Chan
Cleveland Clinic.
Co-authored papers
6
Anirban Maitra
The University of Texas MD Anderson Cancer Center
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5
Pedram Argani
The Johns Hopkins Hospital
Co-authored papers
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Kenneth W Kinzler
Co-authored papers
4
Elizabeth Garrett-Mayer
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Co-authored papers
4
Bert Vogelstein
Co-authored papers
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Joe W Gray
Oregon Health and Science University
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