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Author Details

Stephanie Roessler
Institute of Pathology, University Hospital Heidelberg
2004
92
31
PMIDPaper TitleJournal TitlePublished Year
36932115Hypoxia-responsive PPARGC1A/BAMBI/ACSL5 axis promotes progression and resistance to lenvatinib in hepatocellular carcinoma.Oncogene2023
37562657Deep Learning-Enabled Diagnosis of Liver Adenocarcinoma.Gastroenterology2023
37916976Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC.Hepatology2023
37666725The role of bariatric surgery on beta-cell function and insulin resistance in patients with nonalcoholic fatty liver disease and steatohepatitis.Surg Obes Relat Dis2023
37679568Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC.Nat Cancer2023
37351572A critical spotlight on the paradigms of FFPE-DNA sequencing.Nucleic Acids Res2023
37348162DNA methylation-based classifier differentiates intrahepatic pancreato-biliary tumours.EBioMedicine2023
33468537Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis.Gut2022
35384001New kid on the block: Netrin-1 as a novel player in the delicate molecular network of hepatic inflammation.Hepatology2022
36577757LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence.Oncogenesis2022
35871236Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing.Br J Cancer2022
36068277Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis.Br J Cancer2022
36031387Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2-Dependent Mitotic Cell Death.Adv Sci (Weinh)2022
35983950Bcl-x<sub>L</sub> as prognostic marker and potential therapeutic target in cholangiocarcinoma.Liver Int2022
35132819miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver.Hepatol Commun2022
34996827Blocking hepatocarcinogenesis by a cytochrome P450 family member with female-preferential expression.Gut2022
35267462STAT1 and STAT3 Exhibit a Crosstalk and Are Associated with Increased Inflammation in Hepatocellular Carcinoma.Cancers (Basel)2022
35053620HELLS Is Negatively Regulated by Wild-Type P53 in Liver Cancer by a Mechanism Involving P21 and FOXM1.Cancers (Basel)2022
35076948Therapeutic efficacy of FASN inhibition in preclinical models of HCC.Hepatology2022
32378092Impact of Type 2 Diabetes on Oncologic Outcomes of Hepatocellular Carcinomas in Non-Cirrhotic, Non-alcoholic Steatohepatitis: a Matched-Pair Analysis.J Gastrointest Surg2021
33918309Programmed Death Ligand-1 (PD-L1) Is an Independent Negative Prognosticator in Western-World Gallbladder Cancer.Cancers (Basel)2021
33608169Integrative genomics highlights opportunities for innovative therapies targeting the tumor microenvironment in gallbladder cancer.J Hepatol2021
34615513Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma.BMC Cancer2021
34627652Corrigendum to 'Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis' [J Hepatol 75 (2021) 865-878].J Hepatol2021
34419953Development and Validation of a Novel Scoring System for Noninvasive Nonalcoholic Steatohepatitis Detection in Bariatric Patients.Obes Facts2021
33992698Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis.J Hepatol2021
34282029Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer.Cancer Discov2021
32609900MiR-125b Loss Activated HIF1α/pAKT Loop, Leading to Transarterial Chemoembolization Resistance in Hepatocellular Carcinoma.Hepatology2021
32899426RNA Sequencing of Hepatobiliary Cancer Cell Lines: Data and Applications to Mutational and Transcriptomic Profiling.Cancers (Basel)2020
32055024NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis.Oncogene2020
31838585HER2 gene (ERBB2) amplification is a low-frequency driver with potential predictive value in gallbladder carcinoma.Virchows Arch2020
31925805Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities.Hepatology2020
33257655Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria.Cell Death Dis2020
33256802Loss of miR-192-5p initiates a hyperglycolysis and stemness positive feedback in hepatocellular carcinoma.J Exp Clin Cancer Res2020
33087321YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis.Cancer Res2020
32799415Synchronised infection identifies early rate-limiting steps in the hepatitis B virus life cycle.Cell Microbiol2020
32710569miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis.J Pathol2020
32737464Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.Nat Protoc2020
30615206Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.Hepatology2019
31783876Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer.Cell Commun Signal2019
31805897HER2 gene (ERBB2) amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesis.BMC Cancer2019
31832586Outcome after liver resection for primary and recurrent intrahepatic cholangiocarcinoma.BJS Open2019
30867471Prognostic Impact of Carboxylesterase 2 in Cholangiocarcinoma.Sci Rep2019
31068195Low frequency of mismatch repair deficiency in gallbladder cancer.Diagn Pathol2019
30918010A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.Life Sci Alliance2019
30886199Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p.Sci Rep2019
30829432Molecular perturbations in cholangiocarcinoma: Is it time for precision medicine?Liver Int2019
31089132Nucleoporin Nup155 is part of the p53 network in liver cancer.Nat Commun2019
31001651Random gene sets in predicting survival of patients with hepatocellular carcinoma.J Mol Med (Berl)2019
30782401NUT carcinoma in a nutshell: A diagnosis to be considered more frequently.Pathol Res Pract2019
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Collaborators

Peter Schirmacher
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 42
Xin Wei Wang
Center for Cancer Research, National Cancer Institute (NCI)
Co-authored papers 16
Thomas Albrecht
Institute of Pathology, Heidelberg University Hospital
Co-authored papers 14
Albrecht Stenzinger
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 8
Alessandro Ori
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
Co-authored papers 7
Snorri S Thorgeirsson
Co-authored papers 7
Thomas Longerich
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 7
Arndt Vogel
Clinic for Gastroenterology, Medical University Hannover
Co-authored papers 5
Lars Zender
Co-authored papers 4
Volker Endris
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 4
Rudolf Grosschedl
Co-authored papers 4
Esther Herpel
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 3
Christoph Plass
German Cancer Research Center
Co-authored papers 3
Martin Beck
Max Planck Institute of Biophysics
Co-authored papers 3
Dieter Weichenhan
German Cancer Research Center (DKFZ)
Co-authored papers 3
Olaf Neumann
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 3
Anna-Lena Volckmar
Institut fur Pathologie, Universitatsklinikum Heidelberg
Co-authored papers 2
Stefan Fr??hling
German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT)
Co-authored papers 2
Yidong Chen
Zhujiang Hospital, Southern Medical University
Co-authored papers 2
Yassen Assenov
German Cancer Research Center (DKFZ)
Co-authored papers 2
Lewis R Roberts
Co-authored papers 2
David Capper
Charite University Medicine Berlin
Co-authored papers 2
Andrew V Uzilov
University of California Santa Cruz
Co-authored papers 2
Daniela Sia
Co-authored papers 2
Benedikt Brors
German Cancer Research Center (DKFZ)
Co-authored papers 2
Andreas von Deimling
Co-authored papers 2
Sebastian Uhrig
National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 2
Martina Kirchner
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Release 1.2