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| 35282732 | A Novel Full-Length Recombinant Human Complement Factor H (CFH; GEM103) for the Treatment of Age-Related Macular Degeneration Shows Similar <i>In Vitro</i> Functional Activity to Native CFH. | Curr Eye Res | 2022 |
| 35655546 | Energetics of a protein disorder-order transition in small molecule recognition. | Chem Sci | 2022 |
| 36445700 | An Evaluation of the Complement-Regulating Activities of Human Complement Factor H (FH) Variants Associated With Age-Related Macular Degeneration. | Invest Ophthalmol Vis Sci | 2022 |
| 35095933 | Editorial: Function and Dysfunction of Complement Factor H. | Front Immunol | 2022 |
| 34054871 | Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice. | Front Immunol | 2021 |
| 33519811 | Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD. | Front Immunol | 2021 |
| 32923173 | Complement inhibitor factor H expressed by breast cancer cells differentiates CD14<sup>+</sup> human monocytes into immunosuppressive macrophages. | Oncoimmunology | 2020 |
| 34084326 | Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A. | Chem Sci | 2020 |
| 30965383 | Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes. | Cell Microbiol | 2019 |
| 29588430 | An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy. | J Am Soc Nephrol | 2018 |
| 29858390 | Grasping the nettle: A bacterial invasin that targets immunoglobulin variable domains. | J Biol Chem | 2018 |
| 29935669 | Genome-Wide Association Studies Identify Disease Mechanisms in Age-Related Macular Degeneration. | Ophthalmology | 2018 |
| 28637873 | Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation. | J Biol Chem | 2017 |
| 26700768 | Recruitment of Factor H as a Novel Complement Evasion Strategy for Blood-Stage Plasmodium falciparum Infection. | J Immunol | 2016 |
| 26643478 | Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation. | J Immunol | 2016 |
| 27976756 | Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes. | Wellcome Open Res | 2016 |
| 27250206 | Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling. | Mol Cell Proteomics | 2016 |
| 25723550 | Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes. | PLoS Pathog | 2015 |
| 26517887 | Creating functional sophistication from simple protein building blocks, exemplified by factor H and the regulators of complement activation. | Biochem Soc Trans | 2015 |
| 26459349 | Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement. | J Immunol | 2015 |
| 24214979 | Using mutagenesis and structural biology to map the binding site for the Plasmodium falciparum merozoite protein PfRh4 on the human immune adherence receptor. | J Biol Chem | 2014 |
| 24722444 | Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN. | J Am Soc Nephrol | 2014 |
| 24323885 | Decoding the components of dynamics in three-domain proteins. | J Comput Chem | 2014 |
| 22795972 | New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties. | Immunobiology | 2013 |
| 23616575 | Rational engineering of a minimized immune inhibitor with unique triple-targeting properties. | J Immunol | 2013 |
| 23701234 | Functional anatomy of complement factor H. | Biochemistry | 2013 |
| 23204401 | Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis. | J Am Soc Nephrol | 2013 |
| 23054935 | ¹H, ¹³C and ¹âµN resonance assignments of the complement control protein modules of the complement component C7. | Biomol NMR Assign | 2013 |
| 22389686 | Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH). | PLoS One | 2012 |
| 23017427 | Solution structure of CCP modules 10-12 illuminates functional architecture of the complement regulator, factor H. | J Mol Biol | 2012 |
| 22721707 | Factor H autoantibodies in membranoproliferative glomerulonephritis. | Mol Immunol | 2012 |
| 22843697 | The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution. | J Biol Chem | 2012 |
| 22506052 | Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria. | PLoS One | 2012 |
| 22320225 | Structural and functional characterization of the product of disease-related factor H gene conversion. | Biochemistry | 2012 |
| 20586101 | The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation. | J Mol Recognit | 2011 |
| 21793561 | Estimation of interdomain flexibility of N-terminus of factor H using residual dipolar couplings. | Biochemistry | 2011 |
| 21936007 | Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus). | Protein Sci | 2011 |
| 21685372 | Plasmodium falciparum uses a key functional site in complement receptor type-1 for invasion of human erythrocytes. | Blood | 2011 |
| 21697597 | Crystallographic determination of the disease-associated T1184R variant of complement regulator factor H. | Acta Crystallogr D Biol Crystallogr | 2011 |
| 21317894 | Structural basis for engagement by complement factor H of C3b on a self surface. | Nat Struct Mol Biol | 2011 |
| 21146613 | Production of biologically active complement factor H in therapeutically useful quantities. | Protein Expr Purif | 2011 |
| 21270465 | Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities. | J Biol Chem | 2011 |
| 19835885 | The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module. | J Mol Biol | 2010 |
| 20855594 | Complement receptor 1 is the host erythrocyte receptor for Plasmodium falciparum PfRh4 invasion ligand. | Proc Natl Acad Sci U S A | 2010 |
| 20515689 | MDM4 binds ligands via a mechanism in which disordered regions become structured. | FEBS Lett | 2010 |
| 20592223 | Complement factor h autoantibodies and age-related macular degeneration. | Invest Ophthalmol Vis Sci | 2010 |
| 20394361 | Lysine and arginine side chains in glycosaminoglycan-protein complexes investigated by NMR, cross-linking, and mass spectrometry: a case study of the factor H-heparin interaction. | J Am Chem Soc | 2010 |
| 19951950 | Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells. | J Biol Chem | 2010 |
| 19861685 | Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome. | Blood | 2010 |
| 19023603 | An interrupted beta-propeller and protein disorder: structural bioinformatics insights into the N-terminus of alsin. | J Mol Model | 2009 |