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Author Details

Agapios Sachinidis
Institute of Neurophysiology, University of Cologne
1985
306
49
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38063256<i>Kcnh2</i> deletion is associated with rat embryonic development defects via destruction of KCNH2⿿integrin β1 complex.Int J Mol Med2024
37767130Whole genome transcriptome data from the WT cortex and hippocampus of female and male control and APP/PS1 Alzheimer's disease mice.Data Brief2023
37656254Myeloperoxidase is a critical mediator of anthracycline-induced cardiomyopathy.Basic Res Cardiol2023
37690743Risk assessment of parabens in a transcriptomics-based in vitro test.Chem Biol Interact2023
37644023Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells.Cell Death Discov2023
34678512IL12 integrated into the CAR exodomain converts CD8<sup>+</sup> T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors.Mol Ther2022
35789849Microgravity-induced stress mechanisms in human stem cell-derived cardiomyocytes.iScience2022
35690874High-efficient serum-free differentiation of endothelial cells from human iPS cells.Stem Cell Res Ther2022
35455960Live-Cell Imaging of the Contractile Velocity and Transient Intracellular Ca<sup>2+</sup> Fluctuations in Human Stem Cell-Derived Cardiomyocytes.Cells2022
35416653Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test.Chem Res Toxicol2022
36335090Epigenetic mechanisms of Strip2 in differentiation of pluripotent stem cells.Cell Death Discov2022
36359802High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation.Cells2022
35099568Correction to: Toxicogenomics directory of chemically exposed human hepatocytes.Arch Toxicol2022
33441788Enhanced hippocampal type II theta activity AND altered theta architecture in mice lacking the Ca<sub>v</sub>3.2 T-type voltage-gated calcium channel.Sci Rep2021
33542080Gene Expression-Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial.Clin Cancer Res2021
34572125Detection of Novel Potential Regulators of Stem Cell Differentiation and Cardiogenesis through Combined Genome-Wide Profiling of Protein-Coding Transcripts and microRNAs.Cells2021
34831333Application of the Pluripotent Stem Cells and Genomics in Cardiovascular Research-What We Have Learnt and Not Learnt until Now.Cells2021
33987212Epigenetic Mechanisms Involved in the Cardiovascular Toxicity of Anticancer Drugs.Front Cardiovasc Med2021
34091588High-throughput base editing: a promising technology for precision medicine and drug discovery.Signal Transduct Target Ther2021
33426760ERG1 plays an essential role in rat cardiomyocyte fate decision by mediating AKT signaling.Stem Cells2021
33419458Persistence of intramyocardially transplanted murine induced pluripotent stem cell-derived cardiomyocytes from different developmental stages.Stem Cell Res Ther2021
31603587Functional implications of Ca<sub>v</sub> 2.3 R-type voltage-gated calcium channels in the murine auditory system - novel vistas from brainstem-evoked response audiometry.Eur J Neurosci2020
31919559Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.Arch Toxicol2020
31712839Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances.Arch Toxicol2020
33312107Genome-wide expression changes induced by bisphenol A, F and S in human stem cell derived hepatocyte-like cells.EXCLI J2020
33245762Kinetic modeling of stem cell transcriptome dynamics to identify regulatory modules of normal and disturbed neuroectodermal differentiation.Nucleic Acids Res2020
32660081Radiation Response of Murine Embryonic Stem Cells.Cells2020
32987940Correction: Nemade, H.; et al. Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. <i>Cells</i> 2020, <i>9</i>, 554.Cells2020
32120775Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells.Cells2020
32316481Cardiotoxicity and Heart Failure: Lessons from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Anticancer Drugs.Cells2020
30554961yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs.Cell Stem Cell2019
31695764Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations.Theranostics2019
31503410GSK-3β inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity.J Cell Mol Med2019
31555647<i>IGF2</i> mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis.Front Med (Lausanne)2019
31378782Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants.Cell Death Dis2019
31250071Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.Arch Toxicol2019
31130451Road Map for Development of Stem Cell-Based Alternative Test Methods.Trends Mol Med2019
31013958Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes.Cells2019
30894204Gender specific click and tone burst evoked ABR datasets from mice lacking the Ca<sub>v</sub>3.2 T-type voltage-gated calcium channel.BMC Res Notes2019
30862552Cardiomyocytes facing fibrotic conditions re-express extracellular matrix transcripts.Acta Biomater2019
30886000Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart.EMBO Rep2019
31029730Ca<sub>v</sub>3.2 T-Type Calcium Channels Are Physiologically Mandatory for the Auditory System.Neuroscience2019
31083689Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis.PLoS One2019
30907509Laminin promotes differentiation of rat embryonic stem cells into cardiomyocytes by activating the integrin/FAK/PI3K p85 pathway.J Cell Mol Med2019
31052294Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications.Cells2019
31132044Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice.J Vis Exp2019
28940058Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes.Arch Toxicol2018
30195755Parallel Genome-wide Profiling of Coding and Non-coding RNAs to Identify Novel Regulatory Elements in Embryonic and Maturated Heart.Mol Ther Nucleic Acids2018
30456242Gender specific click and tone burst evoked ABR datasets from mice lacking the Ca<sub>v</sub>2.3 R-type voltage-gated calcium channel.Data Brief2018
30511339Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.Arch Toxicol2018
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Collaborators

Institute of Neurophysiology, University of Cologne
Co-authored papers 118
Medizinische Universitats-Poliklinik
Co-authored papers 90
Medical University of Vienna
Co-authored papers 34
BioMarin Pharmaceutical Inc.
Co-authored papers 34
Research Centre, Ananda College
Co-authored papers 32
TU Dortmund University
Co-authored papers 24
University Clinics of Cologne
Co-authored papers 16
Clinic for Plastic, Otto von Guericke University
Co-authored papers 14
Institute of Neurophysiology
Co-authored papers 13
Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund
Co-authored papers 13
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 7
Institute of Neurophysiology, University of Cologne
Co-authored papers 7
Institute of Computer Science, University of Tartu
Co-authored papers 5
Tongji Medical College
Co-authored papers 4
Maastricht University
Co-authored papers 4
Institute of Computer Science, University of Tartu
Co-authored papers 3
University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Co-authored papers 3
Medical Faculty and University Hospital Carl Gustav Carus
Co-authored papers 2
Royal Institute of Technology Science for Life Laboratory Stockholm Sweden.
Co-authored papers 2
Center for Molecular and Cellular Bioengineering, Technische Universitat Dresden
Co-authored papers 2
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 2
Federal Institute for Drugs and Medical Devices (BfArM)
Co-authored papers 2
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Fort Valley State University
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Co-authored papers 2
University Medical Center Hamburg-Eppendorf
Co-authored papers 2
Co-authored papers 2
Spanish National Cancer Research Centre-CNIO
Co-authored papers 1
Faculty of Medicine and University Hospital Carl Gustav Carus
Co-authored papers 1