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Author Details

Lan Huang
University of California Irvine
1994
161
51
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36543169Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.Structure2023
38019907Lipid-anchored proteasomes control membrane protein homeostasis.Sci Adv2023
37904046Structural surfaceomics reveals an AML-specific conformation of integrin β<sub>2</sub> as a CAR T cellular therapy target.Nat Cancer2023
37410820Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.Science2023
37406423New advances in cross-linking mass spectrometry toward structural systems biology.Curr Opin Chem Biol2023
37214989Molecular mechanisms for activation of the 26S proteasome.bioRxiv2023
37214852Lipid-anchored Proteasomes Control Membrane Protein Homeostasis.bioRxiv2023
36652389Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.Anal Chem2023
37439247Mapping Pregnancy-dependent Sulfhydrome Unfolds Diverse Functions of Protein Sulfhydration in Human Uterine Artery.Endocrinology2023
36543169Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.Structure2023
38019907Lipid-anchored proteasomes control membrane protein homeostasis.Sci Adv2023
37904046Structural surfaceomics reveals an AML-specific conformation of integrin β<sub>2</sub> as a CAR T cellular therapy target.Nat Cancer2023
37214989Molecular mechanisms for activation of the 26S proteasome.bioRxiv2023
37214852Lipid-anchored Proteasomes Control Membrane Protein Homeostasis.bioRxiv2023
37410820Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.Science2023
37439247Mapping Pregnancy-dependent Sulfhydrome Unfolds Diverse Functions of Protein Sulfhydration in Human Uterine Artery.Endocrinology2023
37406423New advances in cross-linking mass spectrometry toward structural systems biology.Curr Opin Chem Biol2023
36652389Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.Anal Chem2023
34763062The Ubiquitin Interacting Motif-Like Domain of Met4 Selectively Binds K48 Polyubiquitin Chains.Mol Cell Proteomics2022
35948006Discovery of compounds that reactivate p53 mutants in vitro and in vivo.Cell Chem Biol2022
35927584Yeast PI31 inhibits the proteasome by a direct multisite mechanism.Nat Struct Mol Biol2022
35292538Structure and conformational dynamics of <i>Clostridioides difficile</i> toxin A.Life Sci Alliance2022
35235311Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.Anal Chem2022
35193351Developing a Targeted Quantitative Strategy for Sulfoxide-Containing MS-Cleavable Cross-Linked Peptides to Probe Conformational Dynamics of Protein Complexes.Anal Chem2022
35027733The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.Nat Cell Biol2022
35174153Editorial: Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications.Front Cell Dev Biol2022
34962381Characterization of <i>In Vivo</i> Protein Complexes <i>via</i> Chemical Cross-Linking and Mass Spectrometry.Anal Chem2022
34763062The Ubiquitin Interacting Motif-Like Domain of Met4 Selectively Binds K48 Polyubiquitin Chains.Mol Cell Proteomics2022
35927584Yeast PI31 inhibits the proteasome by a direct multisite mechanism.Nat Struct Mol Biol2022
35948006Discovery of compounds that reactivate p53 mutants in vitro and in vivo.Cell Chem Biol2022
35174153Editorial: Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications.Front Cell Dev Biol2022
35027733The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.Nat Cell Biol2022
35235311Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.Anal Chem2022
34962381Characterization of <i>In Vivo</i> Protein Complexes <i>via</i> Chemical Cross-Linking and Mass Spectrometry.Anal Chem2022
35292538Structure and conformational dynamics of <i>Clostridioides difficile</i> toxin A.Life Sci Alliance2022
35193351Developing a Targeted Quantitative Strategy for Sulfoxide-Containing MS-Cleavable Cross-Linked Peptides to Probe Conformational Dynamics of Protein Complexes.Anal Chem2022
34314389Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1.JCI Insight2021
34145250Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.Nat Commun2021
33603165Proteasome regulation by reversible tyrosine phosphorylation at the membrane.Oncogene2021
33602808Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.Proc Natl Acad Sci U S A2021
34349018Protein interaction landscapes revealed by advanced in vivo cross-linking-mass spectrometry.Proc Natl Acad Sci U S A2021
34314389Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1.JCI Insight2021
33915260Enabling Photoactivated Cross-Linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-Cleavable Cross-Linkers.Mol Cell Proteomics2021
34389466Characterization of an A3G-Vif<sub>HIV-1</sub>-CRL5-CBFβ Structure Using a Cross-linking Mass Spectrometry Pipeline for Integrative Modeling of Host-Pathogen Complexes.Mol Cell Proteomics2021
34609515Purification of MAP-kinase protein complexes and identification of candidate components by XL-TAP-MS.Plant Physiol2021
34550675Developing a Bimolecular Affinity Purification Strategy to Isolate 26S Proteasome Holocomplexes for Complex-Centric Proteomic Analysis.Anal Chem2021
34761751Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions.Elife2021
33603165Proteasome regulation by reversible tyrosine phosphorylation at the membrane.Oncogene2021
33602808Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.Proc Natl Acad Sci U S A2021
33915260Enabling Photoactivated Cross-Linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-Cleavable Cross-Linkers.Mol Cell Proteomics2021
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Collaborators

Clinton Yu
University of California Irvine
Co-authored papers 45
Xiaorong Wang
University of California Irvine
Co-authored papers 38
Alma L Burlingame
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 25
Scott D Rychnovsky
University of California irvine
Co-authored papers 22
Robyn M Kaake
J. David Gladstone Institutes
Co-authored papers 15
Yingying Yang
University of California irvine
Co-authored papers 14
Craig B Gutierrez
University of California irvine
Co-authored papers 9
Eric J Novitsky
University of California irvine
Co-authored papers 8
Xing Guo
Life Sciences Institute, Zhejiang University
Co-authored papers 7
Liye Zhang
ShanghaiTech University
Co-authored papers 7
Alexander S Huszagh
University of California irvine
Co-authored papers 6
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 5
Rosa Viner
University of California (Davis)
Co-authored papers 5
Robert J Chalkley
Department of Pharmaceutical Chemistry, University of California at San Francisco
Co-authored papers 5
Connie R Jimenez
Co-authored papers 5
Ning Zheng
University of Washington
Co-authored papers 4
Sung-Hou Kim
University of California berkeley
Co-authored papers 4
Jack E Dixon
University of California
Co-authored papers 4
Alexander Leitner
ETH Zurich
Co-authored papers 3
Stefano Monti
Co-authored papers 3
Ilan E Chemmama
University of California san francisco
Co-authored papers 3
Sarah A Block
University of California irvine
Co-authored papers 3
Michael R Hoopmann
Institute for Systems Biology
Co-authored papers 3
Andrea Sinz
Center for Structural Mass Spectrometry, Martin Luther University Halle-Wittenberg
Co-authored papers 3
Robert L Moritz
Institute for Systems Biology
Co-authored papers 3
Christoph H Borchers
McGill University
Co-authored papers 2
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 2
Karl Mechtler
IMP-Institute of Molecular Pathology
Co-authored papers 2
Albert J R Heck
Utrecht University
Co-authored papers 2
Michael G??tze
and Pharmacy, Freie Universitat Berlin
Co-authored papers 2
Release 1.2