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Author Details

Mirit I Aladjem
National Cancer Institute, Center for Cancer Research
1988
129
40
PMIDPaper TitleJournal TitlePublished Year
36715552Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.Cancer Discov2023
37824137Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer: A Randomized Clinical Trial.JAMA Oncol2023
37998365SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci.Cells2023
37612584RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter.Cell Commun Signal2023
37216280Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication.Mol Cancer Ther2023
36715552Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.Cancer Discov2023
37461562RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter.Res Sq2023
36924503Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B.Cell Rep2023
37227187Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial.Clin Cancer Res2023
37998365SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci.Cells2023
37612584RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter.Cell Commun Signal2023
37824137Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer: A Randomized Clinical Trial.JAMA Oncol2023
37216280Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication.Mol Cancer Ther2023
37227187Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial.Clin Cancer Res2023
37461562RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter.Res Sq2023
36924503Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B.Cell Rep2023
34625299Preventing excess replication origin activation to ensure genome stability.Trends Genet2022
35463463DNA replication profiling by molecular combing on single DNA fibers.STAR Protoc2022
35524559Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy.Nucleic Acids Res2022
36368157The differentially expressed gene signatures of the Cullin 3-RING ubiquitin ligases in neuroendocrine cancer.Biochem Biophys Res Commun2022
35387667Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I.J Exp Clin Cancer Res2022
36093297Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma.Oncotarget2022
36342127Context-Dependent Function of Long Noncoding RNA <i>PURPL</i> in Transcriptome Regulation during p53 Activation.Mol Cell Biol2022
36325065Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.iScience2022
36381660Replication stress defines distinct molecular subtypes across cancers.Cancer Res Commun2022
34625299Preventing excess replication origin activation to ensure genome stability.Trends Genet2022
35217604BEND3 safeguards pluripotency by repressing differentiation-associated genes.Proc Natl Acad Sci U S A2022
35463463DNA replication profiling by molecular combing on single DNA fibers.STAR Protoc2022
35524559Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy.Nucleic Acids Res2022
35387667Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I.J Exp Clin Cancer Res2022
36342127Context-Dependent Function of Long Noncoding RNA <i>PURPL</i> in Transcriptome Regulation during p53 Activation.Mol Cell Biol2022
36368157The differentially expressed gene signatures of the Cullin 3-RING ubiquitin ligases in neuroendocrine cancer.Biochem Biophys Res Commun2022
36381660Replication stress defines distinct molecular subtypes across cancers.Cancer Res Commun2022
36093297Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma.Oncotarget2022
36325065Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.iScience2022
35217604BEND3 safeguards pluripotency by repressing differentiation-associated genes.Proc Natl Acad Sci U S A2022
33468559Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells.Mol Cell Biol2021
33857330Switching DCAFs: Beyond substrate receptors.Bioessays2021
33539925SIRT1 stabilizes extrachromosomal gene amplification and contributes to repeat-induced gene silencing.J Biol Chem2021
34171797Molecular double clips within RepID WD40 domain control chromatin binding and CRL4-substrate assembly.Biochem Biophys Res Commun2021
33848478Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.Cancer Cell2021
34112784The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.Nat Commun2021
33468559Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells.Mol Cell Biol2021
34103496Dynamics of replication origin over-activation.Nat Commun2021
33196823CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics.Nucleic Acids Res2021
33334821The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma.Genes Dev2021
34745220Encounters in Three Dimensions: How Nuclear Topology Shapes Genome Integrity.Front Genet2021
34828271Histone Variant H2A.J Is Enriched in Luminal Epithelial Gland Cells.Genes (Basel)2021
34645815BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.Nat Commun2021
33848478Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.Cancer Cell2021
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Collaborators

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Center for Cancer Research, National Cancer Institute
Co-authored papers 29
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Co-authored papers 18
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Co-authored papers 16
Augustin Luna
Harvard Medical School
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Michael Ryan
The University of Texas MD Anderson Cancer Center
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Vinodh N Rajapakse
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John N Weinstein
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William C Reinhold
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Co-authored papers 7
Eric E Bouhassira
Albert Einstein College of Medicine
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College of Computing and Informatics, University of North Carolina at Charlotte
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Paul S Meltzer
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Lisa M Miller Jenkins
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Fathi Elloumi
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Sudhir Varma
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Sven Bilke
Center for Cancer Research, National Cancer Institute, National Institutes of Health
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Margot Sunshine
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
Seth M Steinberg
Center for Cancer Research, National Cancer Institute
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Myriam Gorospe
National Institute on Aging (NIA), National Institutes of Health (NIH)
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Manuel S Valenzuela
Meharry Medical College
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Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
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Raj Chari
The National Institutes of Health
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Chris Sander
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Sandra Burkett
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Release 1.2