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Author Details

Michael A Newton
University of Wisconsin School of Medicine and Public Health
1990
117
40
Christopher Churas (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35165892Bayes optimal informer sets for early-stage drug discovery.Biometrics2023
37503118SURROGATE SELECTION OVERSAMPLES EXPANDED T CELL CLONOTYPES.bioRxiv2023
38096050NK cells propagate T cell immunity following in situ tumor vaccination.Cell Rep2023
36672468Notch Signaling Suppresses Melanoma Tumor Development in BRAF/Pten Mice.Cancers (Basel)2023
34245130Multi-ancestral origin of intestinal tumors: Impact on growth, progression, and drug efficacy.Cancer Rep (Hoboken)2022
35690417Molecular characterization of hypoxanthine guanine phosphoribosyltransferase mutant T cells in human blood: The concept of surrogate selection for immunologically relevant cells.Mutat Res Rev Mutat Res2022
35624112SpotClean adjusts for spot swapping in spatial transcriptomics data.Nat Commun2022
36590683SpatialCorr identifies gene sets with spatially varying correlation structure.Cell Rep Methods2022
35999349Role of dual specificity phosphatases (DUSPs) in melanoma cellular plasticity and drug resistance.Sci Rep2022
33616173Dimension constraints improve hypothesis testing for large-scale, graph-associated, brain-image data.Biostatistics2022
35001558Rheumatoid Factor and Anti-Modified Protein Antibody Reactivities Converge on IgG Epitopes.Arthritis Rheumatol2022
34655611Validation of genetic classifiers derived from mouse and human tumors to identify molecular subtypes of colorectal cancer.Hum Pathol2022
33693483MixTwice: large-scale hypothesis testing for peptide arrays by variance mixing.Bioinformatics2021
37332668A COMPOSITIONAL MODEL TO ASSESS EXPRESSION CHANGES FROM SINGLE-CELL RNA-SEQ DATA.Ann Appl Stat2021
31135600Enrichment of melanoma-associated T cells in 6-thioguanine-resistant T cells from metastatic melanoma patients.Melanoma Res2020
30425131MTORC1/2 Inhibition as a Therapeutic Strategy for <i>PIK3CA</i> Mutant Cancers.Mol Cancer Ther2019
31175091Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.Clin Cancer Res2019
31231022Melanoma Progression Inhibits Pluripotency and Differentiation of Melanoma-Derived iPSCs Produces Cells with Neural-like Mixed Dysplastic Phenotype.Stem Cell Reports2019
29511567RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes.Pharmacol Res Perspect2018
30188895The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer.PLoS Genet2018
300612044-HPR Is an Endoplasmic Reticulum Stress Aggravator and Sensitizes Breast Cancer Cells Resistant to TRAIL/Apo2L.Anticancer Res2018
25689105Tumourigenic canine osteosarcoma cell lines associated with frizzled-6 up-regulation and enhanced side population cell frequency.Vet Comp Oncol2017
32355573Riemannian Variance Filtering: An Independent Filtering Scheme for Statistical Tests on Manifold-valued Data.Conf Comput Vis Pattern Recognit Workshops2017
28184015Dual PI3K/mTOR Inhibition in Colorectal Cancers with <i>APC</i> and <i>PIK3CA</i> Mutations.Mol Cancer Res2017
28418000SCnorm: robust normalization of single-cell RNA-seq data.Nat Methods2017
29067210Pilot study of safety and feasibility of DNA microseeding for treatment of spontaneous canine melanoma.Vet Med Sci2017
28556428Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.Aging Cell2017
28654262Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.J Chem Inf Model2017
27609830Subclonal diversity arises early even in small colorectal tumours and contributes to differential growth fates.Gut2017
25643733Osteosarcoma tissues and cell lines from patients with differing serum alkaline phosphatase concentrations display minimal differences in gene expression patterns.Vet Comp Oncol2016
26660085Chromosomal copy number alterations and HPV integration in cervical precancer and invasive cancer.Carcinogenesis2016
27782827A statistical approach for identifying differential distributions in single-cell RNA-seq experiments.Genome Biol2016
27207605Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma.Cancer Immunol Immunother2016
27570475Making the cut: improved ranking and selection for large-scale inference.J R Stat Soc Series B Stat Methodol2016
27006204Correction: Dosage compensation can buffer copy-number variation in wild yeast.Elife2016
26976970Heterochromatin Protein 1 Binding Protein 3 Expression as a Candidate Marker of Intrinsic 5-Fluorouracil Resistance.Anticancer Res2016
26949252Further support for aneuploidy tolerance in wild yeast and effects of dosage compensation on gene copy-number evolution.Elife2016
26919712Advanced Intestinal Cancers often Maintain a Multi-Ancestral Architecture.PLoS One2016
25955966Dosage compensation can buffer copy-number variation in wild yeast.Elife2015
26056290Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling.Proc Natl Acad Sci U S A2015
26056298Single-molecule analysis reveals widespread structural variation in multiple myeloma.Proc Natl Acad Sci U S A2015
25914887Multiset Statistics for Gene Set Analysis.Annu Rev Stat Appl2015
25830335A conserved transcriptional signature of delayed aging and reduced disease vulnerability is partially mediated by SIRT3.PLoS One2015
24196829Dynamic tumor growth patterns in a novel murine model of colorectal cancer.Cancer Prev Res (Phila)2014
24752411Genome-wide analysis of host factors in nodavirus RNA replication.PLoS One2014
24747760A strategy to identify dominant point mutant modifiers of a quantitative trait.G3 (Bethesda)2014
24096387A conditional predictive p-value to compare a multinomial with an overdispersed multinomial in the analysis of T-cell populations.Biostatistics2014
23798428Transformation of epithelial cells through recruitment leads to polyclonal intestinal tumors.Proc Natl Acad Sci U S A2013
24068911Limited agreement of independent RNAi screens for virus-required host genes owes more to false-negative than false-positive factors.PLoS Comput Biol2013
23885787Discovery of structural alterations in solid tumor oligodendroglioma by single molecule analysis.BMC Genomics2013
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Collaborators

University of Wisconsin-Madison
Co-authored papers 10
All India Institute of Medical Sciences
Co-authored papers 5
University of Wisconsin-Madison
Co-authored papers 4
University of Missouri School of Medicine
Co-authored papers 4
University of Wisconsin-Madison
Co-authored papers 4
University of Wisconsin-Madison
Co-authored papers 4
Sage Science Inc.
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
University of Wisconsin-Madison
Co-authored papers 3
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Co-authored papers 2
Icahn School of Medicine at Mount Sinai Hospital.
Co-authored papers 2
Mayo Clinic
Co-authored papers 2
Co-authored papers 1
RTI Health Solutions
Co-authored papers 1
University of Wisconsin-Madison
Co-authored papers 1
Brown School of Public Health
Co-authored papers 1
University of Wisconsin-Madison
Co-authored papers 1
University of Michigan Medical School ann arbor
Co-authored papers 1
University of Wisconsin
Co-authored papers 1
Co-authored papers 1
College of Veterinary Medicine and Biomedical Sciences, Colorado State University
Co-authored papers 1
Florida A&M University
Co-authored papers 1
Morgridge Institute for Research
Co-authored papers 1
National Cancer Institute, National Institutes of Health, Inc.
Co-authored papers 1
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
University of Florida
Co-authored papers 1
Co-authored papers 1
University of California San Diego
Co-authored papers 1