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Author Details

Paul S Aisen
Alzheimer's Therapeutic Research Institute, University of Southern California
1983
409
103
PMIDPaper TitleJournal TitlePublished Year
37932961Plasma Aβ42/Aβ40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.Alzheimers Dement2024
37698424The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022.Alzheimers Dement2024
35946590Recommendations to address key recruitment challenges of Alzheimer's disease clinical trials.Alzheimers Dement2023
37458272Trial of Solanezumab in Preclinical Alzheimer's Disease.N Engl J Med2023
36946443Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab.J Prev Alzheimers Dis2023
37202518Detection and treatment of Alzheimer's disease in its preclinical stage.Nat Aging2023
36748826Expectations and clinical meaningfulness of randomized controlled trials.Alzheimers Dement2023
36710683Evaluation of Blood-Based Plasma Biomarkers as Potential Markers of Amyloid Burden in Preclinical Alzheimer's Disease.J Alzheimers Dis2023
36627206Natural cubic splines for the analysis of Alzheimer's clinical trials.Pharm Stat2023
35971310The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.Alzheimers Dement2023
36209495Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4.Alzheimers Dement2023
35962782Tau positron emission tomography in preclinical Alzheimer's disease.Brain2023
34043269State-of-the-art of lumbar puncture and its place in the journey of patients with Alzheimer's disease.Alzheimers Dement2022
35379951Early-stage Alzheimer disease: getting trial-ready.Nat Rev Neurol2022
35440022Meaningful benefits: a framework to assess disease-modifying therapies in preclinical and early Alzheimer's disease.Alzheimers Res Ther2022
35768339Traumatic brain injury and post-traumatic stress disorder are not associated with Alzheimer's disease pathology measured with biomarkers.Alzheimers Dement2022
35580594Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.Brain2022
35542998Sensitivity of the Preclinical Alzheimer's Cognitive Composite (PACC), PACC5, and Repeatable Battery for Neuropsychological Status (RBANS) to Amyloid Status in Preclinical Alzheimer's Disease -Atabecestat Phase 2b/3 EARLY Clinical Trial.J Prev Alzheimers Dis2022
35542991Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease.J Prev Alzheimers Dis2022
36471006Editorial: We Have Turned the Corner.J Prev Alzheimers Dis2022
36336171Randomised controlled trials for the prevention of cognitive decline or dementia: A systematic review.Ageing Res Rev2022
35224459Corrigendum to: ATRI EDC: a novel cloud-native remote data capture system for large multicenter Alzheimer's disease and Alzheimer's disease-related dementias clinical trials.JAMIA Open2022
35156002ATRI EDC: a novel cloud-native remote data capture system for large multicenter Alzheimer's disease and Alzheimer's disease-related dementias clinical trails.JAMIA Open2022
35155730Impact of sex and <i>APOE</i> ε4 on the association of cognition and hippocampal volume in clinically normal, amyloid positive adults.Alzheimers Dement (Amst)2022
35098978The Ups and Downs of Amyloid in Alzheimer's.J Prev Alzheimers Dis2022
35213778Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI).Alzheimers Dement2022
35197359Associations of Stages of Objective Memory Impairment With Amyloid PET and Structural MRI: The A4 Study.Neurology2022
34581485Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease.Alzheimers Dement2022
33971962Aducanumab produced a clinically meaningful benefit in association with amyloid lowering.Alzheimers Res Ther2021
33682706The Impact of Amyloid Burden and APOE on Rates of Cognitive Impairment in Late Life Depression.J Alzheimers Dis2021
33842885Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers.Brain Commun2021
33778148Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study.Alzheimers Dement (N Y)2021
33551954Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management.Front Neurol2021
34585227Using Digital Tools to Advance Alzheimer's Drug Trials During a Pandemic: The EU/US CTAD Task Force.J Prev Alzheimers Dis2021
34585209Editorial: How Will Aducanumab Approval Impact AD Research?J Prev Alzheimers Dis2021
34430703Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial.Alzheimers Dement (Amst)2021
34661109Brain amyloid burden, sleep, and 24-hour rest/activity rhythms: screening findings from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration Studies.Sleep Adv2021
34018654The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.Alzheimers Dement2021
34155411A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.Nat Med2021
34101785The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (IMPACT-AD): A Novel Clinical Trials Training Program.J Prev Alzheimers Dis2021
34101788Platform Trials to Expedite Drug Development in Alzheimer's Disease: A Report from the EU/US CTAD Task Force.J Prev Alzheimers Dis2021
34101778New Hope for Alzheimer's Disease.J Prev Alzheimers Dis2021
34101781Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data.J Prev Alzheimers Dis2021
34101779Intranasal Insulin Reduces White Matter Hyperintensity Progression in Association with Improvements in Cognition and CSF Biomarker Profiles in Mild Cognitive Impairment and Alzheimer's Disease.J Prev Alzheimers Dis2021
34366337Pilot Evaluation of the Unsupervised, At-Home Cogstate Brief Battery in ADNI-2.J Alzheimers Dis2021
32568366Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.JAMA Neurol2020
33253354BACE inhibition causes rapid, regional, and non-progressive volume reduction in Alzheimer's disease brain.Brain2020
33163609Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study.Alzheimers Dement (Amst)2020
33049114Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease.Alzheimers Dement2020
32920625The Trial-Ready Cohort for Preclinical and Prodromal Alzheimer's Disease (TRC-PAD): Experience from the First 3 Years.J Prev Alzheimers Dis2020
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Collaborators

University of California San Francisco
Co-authored papers 103
Mayo Clinic Rochester
Co-authored papers 94
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Co-authored papers 75
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 60
Brigham and Women's Hospital, Massachusetts General Hospital
Co-authored papers 59
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 51
University of Pennsylvania
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Helen Wills Neuroscience Institute, University of California Berkeley
Co-authored papers 41
Indiana University School of Medicine
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University of California
Co-authored papers 40
Keio University School of Medicine
Co-authored papers 28
Washington University School of Medicine
Co-authored papers 25
Keck School of Medicine (EJ, University of Southern California
Co-authored papers 25
University of California davis
Co-authored papers 23
Brigham and Women's Hospital, Broad Institute Ariadne Labs and Harvard Medical School
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F. Hoffmann-La Roche Ltd
Co-authored papers 22
Stark Neurosciences Research Institute, Indiana University School of Medicine (IUSM)
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Banner Alzheimer's Institute
Co-authored papers 19
University of California davis
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Yale University School of Medicine
Co-authored papers 18
Butler Hospital, and Warren Alpert Medical School of Brown University
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Indiana University School of Medicine
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Indiana University School of Medicine
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University of Pennsylvania
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University of California
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Indiana University School of Medicine
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Washington University School of Medicine
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Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School
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