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Author Details

Michael Graham Espey
National Cancer Institute, National Institutes of Health
1990
110
47
PMIDPaper TitleJournal TitlePublished Year
36366801The NCI Glioblastoma Therapeutics Network (GTN).Neuro Oncol2023
37541280National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities.Lancet Oncol2023
35090025Predictive Radiation Oncology - A New NCI-DOE Scientific Space and Community.Radiat Res2022
35245101Tumor Heterogeneity Research and Innovation in Biologically Based Radiation Therapy From the National Cancer Institute Radiation Research Program Portfolio.J Clin Oncol2022
34348172Overview and Lessons From the Preclinical Chemoradiotherapy Testing Consortium.Int J Radiat Oncol Biol Phys2021
33548337FLASH Radiation Therapy: New Technology Plus Biology Required.Int J Radiat Oncol Biol Phys2021
34378064National Cancer Institute support for targeted alpha-emitter therapy.Eur J Nucl Med Mol Imaging2021
34350377Moving Forward in the Next Decade: Radiation Oncology Sciences for Patient-Centered Cancer Care.JNCI Cancer Spectr2021
32024151Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1.Int J Mol Sci2020
29099651Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems.Annu Rev Pathol2018
28254545Redox relationships in gut-microbiome interactions.Free Radic Biol Med2017
30053241Workshop Report: Modulation of Antitumor Immune Responses by Dietary and Microbial Metabolites.J Natl Cancer Inst2017
27527733Meeting Report: The Role of the Mobilome in Cancer.Cancer Res2016
27120084Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense against Pulmonary Bacterial Infection.Am J Respir Cell Mol Biol2016
25496800Redox physical oncology: intersections between redox and the physical environment in cancer.Free Radic Biol Med2015
23127782Role of oxygen gradients in shaping redox relationships between the human intestine and its microbiota.Free Radic Biol Med2013
24808632Measuring the evolution and output of cross-disciplinary collaborations within the NCI Physical Sciences-Oncology Centers Network.Res Eval2013
24049059Effect of nitric oxide on the anticancer activity of the topoisomerase-active drugs etoposide and adriamycin in human melanoma cells.J Pharmacol Exp Ther2013
23959462The role of antioxidants in the era of cardioâ¿¿oncology.Cancer Chemother Pharmacol2013
23402364Role of nitric oxide in the chemistry and anticancer activity of etoposide (VP-16,213).Chem Res Toxicol2013
23211362Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects.J Pharmacol Exp Ther2013
23067008Ascorbic acid kills Epstein-Barr virus positive Burkitt lymphoma cells and Epstein-Barr virus transformed B-cells in vitro, but not in vivo.Leuk Lymphoma2013
22174395Measurement of plasma volume using fluorescent silica-based nanoparticles.J Appl Physiol (1985)2012
22063270Endoplasmic reticulum stress-mediated inhibition of NSMase2 elevates plasma membrane cholesterol and attenuates NO production in endothelial cells.Biochim Biophys Acta2012
21402145Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer.Free Radic Biol Med2011
22332036Vitamin C: a concentration-function approach yields pharmacology and therapeutic discoveries.Adv Nutr2011
20200446Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice.J Clin Invest2010
20628650Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects.PLoS One2010
20586583Hyperoxia sensing: from molecular mechanisms to significance in disease.J Immunotoxicol2010
19361554Losing and finding a way at C: new promise for pharmacologic ascorbate in cancer treatment.Free Radic Biol Med2009
19843868Comment re: Vitamin C antagonizes the cytotoxic effects of chemotherapy.Cancer Res2009
19864471Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase.Carcinogenesis2009
19619135Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.J Neurochem2009
18445594Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signaling.J Biol Chem2008
18503778Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine.Free Radic Biol Med2008
18678913Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice.Proc Natl Acad Sci U S A2008
18224698Dynamic monitoring of localized tumor oxygenation changes using RF pulsed electron paramagnetic resonance in conscious mice.Magn Reson Med2008
17502596Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo.Proc Natl Acad Sci U S A2007
17977265Association of an endogenous inhibitor of nitric oxide synthase with cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.J Neurosurg2007
16540398Guanylyl cyclase-dependent chemotaxis of endothelial cells in response to nitric oxide gradients.Free Radic Biol Med2006
17178853Asbestos redirects nitric oxide signaling through rapid catalytic conversion to nitrite.Cancer Res2006
17145549Tumor macrophage redox and effector mechanisms associated with hypoxia.Free Radic Biol Med2006
16829532Superoxide fluxes limit nitric oxide-induced signaling.J Biol Chem2006
16910783The activation of metabolites of nitric oxide synthase by metals is both redox and oxygen dependent: a new feature of nitrogen oxide signaling.Antioxid Redox Signal2006
16910780The biphasic nature of nitric oxide responses in tumor biology.Antioxid Redox Signal2006
16971023Malignant glioma progression and nitric oxide.Neurochem Int2006
16540401Discriminating formation of HNO from other reactive nitrogen oxide species.Free Radic Biol Med2006
15643898Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH.J Am Chem Soc2005
16408064The emerging biology of the nitrite anion.Nat Chem Biol2005
16157892Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.Proc Natl Acad Sci U S A2005
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Collaborators

Mark Levine
Molecular and Clinical Nutrition Section
Co-authored papers 11
Julie A Hong
National Cancer Institute, National Institutes of Health
Co-authored papers 5
Edward H Oldfield
National Institutes of Health
Co-authored papers 4
Michael P Vitek
Duke University Medical Center
Co-authored papers 4
Robert K Heaton
University of California
Co-authored papers 2
Ronald J Ellis
University of California
Co-authored papers 2
George Perry
College of Sciences, The University of Texas at San Antonio
Co-authored papers 2
Patricia S Steeg
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Sean E Hanlon
Drew University, National Institutes of Health, Rutgers University New Brunswick, University of North Carolina at Chapel Hill
Co-authored papers 1
Jonathan Franca-Koh
J Craig Venter Institute
Co-authored papers 1
Katrina I Theisz
Center for Strategic Scientific Initiatives, National Cancer Institute
Co-authored papers 1
Pawe?? Sulima
National Institutes of Health, National Institute of Allergy and Infectious Diseases
Co-authored papers 1
Joerg Heeren
Co-authored papers 1
Je-Hyuk Lee
Department of Food and Nutrition, Kongju National University
Co-authored papers 1
Gerald S Shadel
Salk Institute for Biological Studies
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Chauncey D Jones
Center for Strategic Scientific Initiatives, National Cancer Institute
Co-authored papers 1
Joshua D Schnell
National Cancer Institute, USA and Center for Strategic Scientific Initiatives
Co-authored papers 1
Robert W Sobol
University of South Alabama
Co-authored papers 1
Nastaran Z Kuhn
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Giovanni Manfredi
Brain and Mind Research Institute
Co-authored papers 1
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
Jill S Barnholtz-Sloan
National Cancer Institute
Co-authored papers 1
Mark T Gladwin
University of Maryland School of Medicine
Co-authored papers 1
Mariam Eljanne
National Cancer Institute
Co-authored papers 1
Jordi Rodon
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Ettore Appella
Co-authored papers 1
Benjamin M Ellingson
David Geffen School of Medicine, University of California Los Angeles
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Jef D Boeke
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Release 1.2