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Author Details
Full Name
David Bulkley
Affiliation
University of California, San Francisco (UCSF) School of Medicine
ORCID
Career Start Year
2010
Papers
22
H Index
20
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
33974910
Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell
2021
32439795
Ion transport and regulation in a synaptic vesicle glutamate transporter.
Science
2020
33139559
Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit.
Proc Natl Acad Sci U S A
2020
33154106
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science
2020
32817938
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.
bioRxiv
2020
32699850
Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization.
bioRxiv
2020
30914650
Author Correction: Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun
2019
30415841
Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.
Cell
2018
30017701
A simple and robust procedure for preparing graphene-oxide cryo-EM grids.
J Struct Biol
2018
29899465
Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun
2018
28658211
Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature
2017
29236684
Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature
2017
27768895
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.
Cell
2016
25594181
Conformational changes of elongation factor G on the ribosome during tRNA translocation.
Cell
2015
24412368
The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep
2014
25306919
Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol Cell
2014
25104389
Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science
2014
24952594
Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix.
Nat Struct Mol Biol
2014
22422986
Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome.
Science
2012
22630605
Contribution of partial charge interactions and base stacking to the efficiency of primer extension at and beyond abasic sites in DNA.
Biochemistry
2012
22240456
The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome.
J Mol Biol
2012
20876130
Revisiting the structures of several antibiotics bound to the bacterial ribosome.
Proc Natl Acad Sci U S A
2010
1 - 22 of 22
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Howard Hughes Medical Institute, University of California los angeles
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