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Author Details

Christopher C Silliman
Vitalant Research Institute
1987
299
63
PMIDPaper TitleJournal TitlePublished Year
37733304Mitigation of trauma-induced endotheliopathy by activated protein C: A potential therapeutic for postinjury thromboinflammation.J Trauma Acute Care Surg2024
37784230Losing the forest for the trees: The complexities of fibrinolysis will never be explained with one variable alone.J Trauma Acute Care Surg2024
36378232TRAUMA INDUCES INTRAVASCULAR HEMOLYSIS, EXACERBATED BY RED BLOOD CELL TRANSFUSION AND ASSOCIATED WITH DISRUPTED ARGININE-NITRIC OXIDE METABOLISM.Shock2023
37695733METABOLOMIC AND PROTEOMIC CHANGES IN TRAUMA-INDUCED HYPOCALCEMIA.Shock2023
37541795The proteomic and metabolomic signatures of isolated and polytrauma traumatic brain injury.Am J Surg2023
37314576Bradykinin release following trauma and hemorrhagic shock causes pulmonary alveolar leak in a rodent model.J Trauma Acute Care Surg2023
37405823A metabolomic and proteomic analysis of pathologic hypercoagulability in traumatic brain injury patients after dura violation.J Trauma Acute Care Surg2023
37466356Omics markers of platelet transfusion in trauma patients.Transfusion2023
37235734Platelets from blood diversion pouches (DPs) are a suitable alternative for functional, bioenergetic, and metabolomic analyses.Blood Transfus2023
37334680Omics Signatures of Tissue Injury and Hemorrhagic Shock in Swine.Ann Surg2023
36749658REBOA for the Treatment of Blast Polytrauma: Zone 3 Provides Cerebral Perfusion, Attenuates Organ Dysfunction and Reperfusion Coagulopathy Compared to Zone 1 in a Swine Model.J Trauma Acute Care Surg2023
36694329Estradiol provokes hypercoagulability and affects fibrin biology: A mechanistic exploration of sex dimorphisms in coagulation.J Trauma Acute Care Surg2023
36805626A proposed clinical coagulation score for research in trauma-induced coagulopathy.J Trauma Acute Care Surg2023
36464240Beyond uterine atony: characterizing postpartum hemorrhage coagulopathy.Am J Obstet Gynecol MFM2023
36802216OUTCOMES FOLLOWING ZONE 3 AND ZONE 1 AORTIC OCCLUSION FOR THE TREATMENT OF BLUNT PELVIC INJURIES.Shock2023
36730076A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player.J Trauma Acute Care Surg2023
36728345Platelet and cryoprecipitate transfusions from female donors improve coagulopathy in vitro.J Trauma Acute Care Surg2023
36319860Hemorrhagic shock and tissue injury provoke distinct components of trauma-induced coagulopathy in a swine model.Eur J Trauma Emerg Surg2023
33214479Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS.Ann Surg2022
35545808A combat casualty relevant dismounted complex blast injury model in swine.J Trauma Acute Care Surg2022
35610738Postinjury complement C4 activation is associated with adverse outcomes and is potentially influenced by plasma resuscitation.J Trauma Acute Care Surg2022
35690490Zone 1 REBOA in a combat DCBI swine model does not worsen brain injury.Surgery2022
35659185Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength.Platelets2022
36548645SHOCK INDUCES ENDOTHELIAL PERMEABILITY AFTER TRAUMA THROUGH INCREASED ACTIVATION OF RHOA GTPASE.Shock2022
36548640BLOOD TYPE O IS A RISK FACTOR FOR HYPERFIBRINOLYSIS AND MASSIVE TRANSFUSION AFTER SEVERE INJURY.Shock2022
36430297Omics Markers of Red Blood Cell Transfusion in Trauma.Int J Mol Sci2022
36309927A pilot study of the metabolic profiles of apheresis platelets modified by donor age and sex and in vitro short-term incubation with sex hormones.Transfusion2022
35929193Hormones, age, and sex affect platelet responsiveness in vitro.Transfusion2022
34538821The α-globin chain of hemoglobin potentiates tissue plasminogen activator induced hyperfibrinolysis in vitro.J Trauma Acute Care Surg2022
32157340Do not drink and lyse: alcohol intoxication increases fibrinolysis shutdown in injured patients.Eur J Trauma Emerg Surg2021
33548446Whole Blood Thrombin Generation in Severely Injured Patients Requiring Massive Transfusion.J Am Coll Surg2021
33503656Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles.Anesthesiology2021
33278796Effects of Blood Components and Whole Blood in a Model of Severe Trauma-Induced Coagulopathy.J Surg Res2021
3289478428-day thawed plasma maintains α<sub>2</sub> -antiplasmin levels and inhibits tPA-induced fibrinolysis.Vox Sang2021
31441792Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis.Shock2020
31843691Examining the Effect of Hypertonic Saline Administered for Reduction of Intracranial Hypertension on Coagulation.J Am Coll Surg2020
31850983Untangling Sex Dimorphisms in Coagulation: Initial Steps Toward Precision Medicine for Trauma Resuscitation.Ann Surg2020
32339428Tranexamic acid disturbs the dynamics of postinjury fibrinolysis.ANZ J Surg2020
30562328Redefining postinjury fibrinolysis phenotypes using two viscoelastic assays.J Trauma Acute Care Surg2019
31613865Cardiac and Skeletal Muscle Myosin Exert Procoagulant Effects.Shock2019
31522748Whole blood thrombin generation is distinct from plasma thrombin generation in healthy volunteers and after severe injury.Surgery2019
31233444Obesity is associated with postinjury hypercoagulability.J Trauma Acute Care Surg2019
31282773Risk factors, management and prevention of transfusion-related acute lung injury: a comprehensive update.Expert Rev Hematol2019
31221537An update of the transfusion-related acute lung injury (TRALI) definition.Transfus Clin Biol2019
31162329Female platelets have distinct functional activity compared with male platelets: Implications in transfusion practice and treatment of trauma-induced coagulopathy.J Trauma Acute Care Surg2019
31136528Variability in international normalized ratio and activated partial thromboplastin time after injury are not explained by coagulation factor deficits.J Trauma Acute Care Surg2019
30993745A consensus redefinition of transfusion-related acute lung injury.Transfusion2019
30747701Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements.Blood Transfus2019
30601456Severe traumatic brain injury is associated with a unique coagulopathy phenotype.J Trauma Acute Care Surg2019
30677527Trauma Resuscitation Consideration: Sex Matters.J Am Coll Surg2019
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University of Colorado School of Medicine
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University of British Columbia
Co-authored papers 3
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University of California san francisco
Co-authored papers 3
Vitalant Research Institute
Co-authored papers 3
University of Florida Health
Co-authored papers 2
University of Rochester Medical Center
Co-authored papers 2
University of Alabama at Birmingham
Co-authored papers 2
University of Colorado School of Medicine
Co-authored papers 2
Duke University School of Medicine
Co-authored papers 2
Erasmus University Medical Center
Co-authored papers 2
Anesthesia Clinical Research Unit, Mayo Clinic
Co-authored papers 2
University of California
Co-authored papers 2
Division of Clinical Trials and Biostatistics, Mayo Clinic
Co-authored papers 2
University of Amsterdam
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Center for Cellular Engineering, NIH Clinical Center, National Institutes of Health
Co-authored papers 2
Mayo Clinic
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Children's Hospital of Philadelphia
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University of California San Francisco
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