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Author Details

Stefan Fr??hling
German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT)
1996
256
66
PMIDPaper TitleJournal TitlePublished Year
36241862Cancer care in German centers of excellence during the first 2 years of the COVID-19 pandemic.J Cancer Res Clin Oncol2023
37656784BRAF<sup>οβ3-αC</sup> in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability.Sci Adv2023
37481390Long-term quality of life after resection of retroperitoneal soft tissue sarcoma.Eur J Surg Oncol2023
37544709Tumour mutational burden and survival with molecularly matched therapy.Eur J Cancer2023
37690178A 3-dimensional histology computer model of malignant melanoma and its implications for digital pathology.Eur J Cancer2023
37734378Signaling-induced systematic repression of miRNAs uncovers cancer vulnerabilities and targeted therapy sensitivity.Cell Rep Med2023
37641393Precision cancer medicine: Concepts, current practice, and future developments.J Intern Med2023
37532709Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.Nat Commun2023
37455247Implementation of precision medicine in healthcare-A European perspective.J Intern Med2023
37382622A self-supervised vision transformer to predict survival from histopathology in renal cell carcinoma.World J Urol2023
37280276The German Network for Personalized Medicine to enhance patient care and translational research.Nat Med2023
37406166Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.Blood Adv2023
37101762Palbociclib in Acute Leukemias With <i>KMT2A</i>-rearrangement: Results of AMLSG 23-14 Trial.Hemasphere2023
37327584Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD).Transl Oncol2023
37260092Outcome of immunotherapy in adrenocortical carcinoma: a retrospective cohort study.Eur J Endocrinol2023
36888935National Center for Tumor Diseases Precision Oncology Thesaurus for Drugs: A Curated Database for Drugs, Drug Classes, and Drug Targets in Precision Cancer Medicine.JCO Clin Cancer Inform2023
36852573Real-world data for precision cancer medicine-A European perspective.Genes Chromosomes Cancer2023
36808802Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling.Mol Oncol2023
36470093Comprehensive molecular profiling of sarcomas in adolescent and young adult patients: Results of the EORTC SPECTA-AYA international proof-of-concept study.Eur J Cancer2023
36434139The coming decade in precision oncology: six riddles.Nat Rev Cancer2023
36702933Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.Nat Cancer2023
36759549Transcriptome profiling for precision cancer medicine using shallow nanopore cDNA sequencing.Sci Rep2023
34331337Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine.Genes Chromosomes Cancer2022
35643220Biology-guided precision medicine in rare cancers: Lessons from sarcomas and neuroendocrine tumours.Semin Cancer Biol2022
35763870Gene expression-based prediction of pazopanib efficacy in sarcoma.Eur J Cancer2022
35668118MCL1 as putative target in pancreatoblastoma.Virchows Arch2022
35497498BTB<sub>BCL6</sub> dimers as building blocks for reversible drug-induced protein oligomerization.Cell Rep Methods2022
35366909Correction to: Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations.J Transl Med2022
35599019Application of precision medicine in clinical routine in haematology-Challenges and opportunities.J Intern Med2022
35459264Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma.Oncogenesis2022
35597437Precision medicine in cancer: A paradigm shift.Semin Cancer Biol2022
35563565Recurrent Germline Variant in <i>RAD21</i> Predisposes Children to Lymphoblastic Leukemia or Lymphoma.Int J Mol Sci2022
35390650Explainable artificial intelligence in skin cancer recognition: A systematic review.Eur J Cancer2022
35781181Response to letter entitled: Re: Integration of deep learning-based image analysis and genomic data in cancer pathology: A systematic review.Eur J Cancer2022
35621918MGMT inactivation as a new biomarker in patients with advanced biliary tract cancers.Mol Oncol2022
35681079Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD).NPJ Precis Oncol2022
36480778Implementation of Whole-Genome and Transcriptome Sequencing Into Clinical Cancer Care.JCO Precis Oncol2022
36495861Toward defining the clinically actionable genome of metastatic breast cancer.Med2022
35973360Model soups improve performance of dermoscopic skin cancer classifiers.Eur J Cancer2022
35871236Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing.Br J Cancer2022
36274133Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards.BMC Med2022
35864412Molecular matched targeted therapies for primary brain tumors-a single center retrospective analysis.J Neurooncol2022
35983950Bcl-x<sub>L</sub> as prognostic marker and potential therapeutic target in cholangiocarcinoma.Liver Int2022
35887198Specific Targeting of Antiapoptotic Bcl-2 Proteins as a Radiosensitizing Approach in Solid Tumors.Int J Mol Sci2022
35918329Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity.Nat Commun2022
35916701Uncertainty Estimation in Medical Image Classification: Systematic Review.JMIR Med Inform2022
36252999IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells.J Immunother Cancer2022
35976907Deep learning can predict survival directly from histology in clear cell renal cell carcinoma.PLoS One2022
33581189Diagnostic performance of artificial intelligence for histologic melanoma recognition compared to 18 international expert pathologists.J Am Acad Dermatol2022
35188570ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats.Nucleic Acids Res2022
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Collaborators

Institute of Pathology, University Hospital Heidelberg
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Berlin Institute of Health at Charite-Universitatsmedizin Berlin
Co-authored papers 43
German Cancer Research Center (DKFZ)
Co-authored papers 42
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Co-authored papers 39
Institute of Pathology, University Hospital Heidelberg
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National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 30
Institute of Pathology, University Hospital Heidelberg
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Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM)
Co-authored papers 22
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German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
Co-authored papers 20
Co-authored papers 19
Institute of Pathology, Heidelberg University Hospital
Co-authored papers 18
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 17
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 16
Institut fur Pathologie, Universitatsklinikum Heidelberg
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German Cancer Research Center (DKFZ)
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Institut fur Pathologie, Universitatsklinikum Heidelberg
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Institute of Pathology, Ludwig-Maximilians-Universitat Munchen
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University of Augsburg
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German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK)
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Berlin Institute of Health (BIH) and Charite
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University of Cambridge
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Institut fur Pathologie, Universitatsmedizin Mannheim
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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Broad Institute of MIT and Harvard
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University Hospital of Schleswig-Holstein
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