Author details

Full Name

Shai S Shen-Orr

Affiliation

ORCID

Career Start Year

2001

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37344505	Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs.		2023
35143619	Identification of Gene Expression Profiles Associated with an Increased Risk of Post-Operative Recurrence in Crohn's Disease.		2022
35675822	Mature neutrophils and a NF-ÎºB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19.	Cell Rep Med	2022
36876140	Immune checkpoint expression and relationships to anti-PD-L1 immune checkpoint blockade cancer immunotherapy efficacy in aged versus young mice.		2022
36471343	Investigating the potential of a prematurely aged immune phenotype in severely injured patients as predictor of risk of sepsis.	Immunity and Ageing	2022
34344783	Antibiotic use differentially affects the risk of anti-drug antibody formation during anti-TNFÎ± therapy in inflammatory bowel disease patients: a report from the epi-IIRN.	Gut	2022
32907803	Response to: 'Tofacitinib for the treatment of polyarteritis nodosa: a literature review'. Correspondence on 'Tofacitinib for polyarteritis nodosa: a tailored therapy' by Rimar .	Annals of the Rheumatic Diseases	2022
34624253	Alignment of single-cell trajectories by tuMap enables high-resolution quantitative comparison of cancer samples.		2022
34888528	An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.	Nat Aging	2021
37117770	Author Correction: An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.	Nat Aging	2021
34140316	IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells.	J Immunother Cancer	2021
33649106	Shaping Functional Avidity of CAR T Cells: Affinity, Avidity, and Antigen Density That Regulate Response.	Molecular Cancer Therapeutics	2021
32843492	IL-31 induces antitumor immunity in breast carcinoma.	Journal for ImmunoTherapy of Cancer	2020
32043328	Autologous Hematological Stem Cell Transplantation for Systemic Sclerosis in Israel.	Israel Medical Association Journal	2020
31145734	Simulation of single-protein nanopore sensing shows feasibility for whole-proteome identification.	PLoS Computational Biology	2019
31708922	Pregnancy-Induced Alterations in NK Cell Phenotype and Function.	Front Immunol	2019
30604764	Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response.	Nat Commun	2019
30634576	CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis.	Journal of Clinical Medicine	2019
29618496	Cell-centred meta-analysis reveals baseline predictors of anti-TNFÎ± non-response in biopsy and blood of patients with IBD.	Gut	2019
31138121	Batch correction evaluation framework using a-priori gene-gene associations: applied to the GTEx dataset.	BMC Bioinformatics	2019
31522890	UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma.	Cell	2019
31401142	Infliximab-Tumor Necrosis Factor Complexes Elicit Formation of Anti-Drug Antibodies.	Gastroenterology	2019
30842675	A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring.	Nat Med	2019
29367465	Inflammatory macrophage-associated 3-gene signature predicts subclinical allograft injury and graft survival.	JCI Insight	2018
30310101	The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis.	Scientific Reports	2018
30401431	UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems.	Molecular Cell	2018
29912209	Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed.	Nat Biotechnol	2018
30478323	Found In Translation: a machine learning model for mouse-to-human inference.	Nature Methods	2018
30232010	Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis.	Cell Rep	2018
29485622	ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.	Sci Data	2018
29529018	Alignment of single-cell trajectories to compare cellular expression dynamics.	Nature Methods	2018
28263321	Social network architecture of human immune cells unveiled by quantitative proteomics.	Nat Immunol	2017
27667365	A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.	Cell Syst	2016
27346348	A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency.	Cell Reports	2016
27376577	Activation of the reward system boosts innate and adaptive immunity.	Nature Medicine	2016
27746093	Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans.	Cell Syst	2016
27558986	Tofacitinib for polyarteritis nodosa: a tailored therapy.	Annals of the Rheumatic Diseases	2016
26682988	Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures.	Immunity	2015
25594173	Variation in the human immune system is largely driven by non-heritable influences.	Cell	2015
25834109	Cytomegalovirus infection enhances the immune response to influenza.	Sci Transl Med	2015
25738455	Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.		2015
25355795	Systems immunology reveals markers of susceptibility to West Nile virus infection.	Clin Vaccine Immunol	2015
24489091	Antigen-dependent integration of opposing proximal TCR-signaling cascades determines the functional fate of T lymphocytes.	J Immunol	2014
23591775	Apoptosis and other immune biomarkers predict influenza vaccine responsiveness.	Mol Syst Biol	2013
23953808	Variability in the immune system: of vaccine responses and immune states.		2013
24148234	Computational deconvolution: extracting cell type-specific information from heterogeneous samples.		2013
24146609	Reconstructing the genomic content of microbiome taxa through shotgun metagenomic deconvolution.	PLoS Computational Biology	2013
23908847	Challenges and promise for the development of human immune monitoring.	Rambam Maimonides Medical Journal	2012
22647780	New tools for classification and monitoring of autoimmune diseases.	Nature reviews. Rheumatology	2012
22323610	Significance analysis of xMap cytokine bead arrays.	Proceedings of the National Academy of Sciences of the United States of America	2012