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Author Details

James C Cloyd
University of Minnesota Twin Cities
1978
148
35
PMIDPaper TitleJournal TitlePublished Year
36950806Tau Phosphorylation Patterns in the Rat Cerebral Cortex After Traumatic Brain Injury and Sodium Selenate Effects: An Epibios4rx Project 2 Study.J Neurotrauma2024
36609129Why ketamine.Epilepsy Behav2023
37316328Levetiracetam Pharmacokinetics and Brain Uptake in a Lateral Fluid Percussion Injury Rat Model.J Pharmacol Exp Ther2023
37442737Comment on the formulation of intravenous topiramate for the treatment of status epilepticus.Epilepsy Behav2023
34558098Translational and clinical pharmacology considerations in drug repurposing for X-linked adrenoleukodystrophy-A rare peroxisomal disorder.Br J Clin Pharmacol2022
35357690Estimating the National Population of Hospitalized Chronic Baclofen Users: A Cross-Sectional Analysis of a Commercial Claims Database.Drugs Real World Outcomes2022
36012454Biological Variation in Peripheral Inflammation and Oxidative Stress Biomarkers in Individuals with Gaucher Disease.Int J Mol Sci2022
34862270Intravenous and Intramuscular Allopregnanolone for Early Treatment of Status Epilepticus: Pharmacokinetics, Pharmacodynamics, and Safety in Dogs.J Pharmacol Exp Ther2022
33336359Early Exposure of Fosphenytoin, Levetiracetam, and Valproic Acid After High-Dose Intravenous Administration in Young Children With Benzodiazepine-Refractory Status Epilepticus.J Clin Pharmacol2021
33742783A pharmacokinetic simulation study to assess the performance of a sparse blood sampling approach to quantify early drug exposure.Clin Transl Sci2021
33567109Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial.Epilepsia2021
33617690Overcoming the challenges of developing an intranasal diazepam rescue therapy for the treatment of seizure clusters.Epilepsia2021
33804401Quantitative Assessment of Occipital Metabolic and Energetic Changes in Parkinson's Patients, Using In Vivo <sup>31</sup>P MRS-Based Metabolic Imaging at 7T.Metabolites2021
34275158Population Pharmacokinetic Analysis of N-Acetylcysteine in Pediatric Patients With Inherited Metabolic Disorders Undergoing Hematopoietic Stem Cell Transplant.J Clin Pharmacol2021
34036177Identifying Biological Signatures of N-Acetylcysteine for Non-Suicidal Self-Injury in Adolescents and Young Adults.J Psychiatr Brain Sci2021
34032604Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus.Neurology2021
34330615Characterizing Baclofen Withdrawal: A National Survey of Physician Experience.Pediatr Neurol2021
31613991Neurochemical abnormalities in patients with type 1 Gaucher disease on standard of care therapy.J Inherit Metab Dis2020
32052462Pharmacokinetics, Safety, and Tolerability of Orally Administered Ursodeoxycholic Acid in Patients With Parkinson's Disease-A Pilot Study.J Clin Pharmacol2020
31761523GBA1 mutations: Prospects for exosomal biomarkers in α-synuclein pathologies.Mol Genet Metab2020
33335836Patients with Gaucher disease display systemic oxidative stress dependent on therapy status.Mol Genet Metab Rep2020
32717964N-acetylcysteine Provides Cytoprotection in Murine Oligodendrocytes through Heme Oxygenase-1 Activity.Biomedicines2020
32420641The association of patient weight and dose of fosphenytoin, levetiracetam, and valproic acid with treatment success in status epilepticus.Epilepsia2020
31161706Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial.Acad Emerg Med2019
31774955Randomized Trial of Three Anticonvulsant Medications for Status Epilepticus.N Engl J Med2019
30837282Intranasal Coadministration of a Diazepam Prodrug with a Converting Enzyme Results in Rapid Absorption of Diazepam in Rats.J Pharmacol Exp Ther2019
28940353Repeated-Dose Oral N-Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress.J Clin Pharmacol2018
30159892Rescue therapies for seizure emergencies: New modes of administration.Epilepsia2018
30227158Conversion of a soluble diazepam prodrug to supersaturated diazepam for rapid intranasal delivery: Kinetics and stability.J Control Release2018
27867020A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics.PM R2017
26943947Clinical utility of topiramate extended-release capsules (USL255): Bioequivalence of USL255 sprinkled and intact capsule in healthy adults and an in vitro evaluation of sprinkle delivery via enteral feeding tubes.Epilepsy Behav2016
26395889Pharmacokinetic-Pharmacodynamic Modeling of Intravenous and Oral Topiramate and Its Effect on the Symbol-Digit Modalities Test in Adult Healthy Volunteers.J Clin Pharmacol2016
27683846Deconstructing tolerance with clobazam: Post hoc analyses from an open-label extension study.Neurology2016
27995128Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy.Front Vet Sci2016
27397490A review of intranasal formulations for the treatment of seizure emergencies.J Control Release2016
27547896A hierarchical Bayesian approach for combining pharmacokinetic/pharmacodynamic modeling and Phase IIa trial design in orphan drugs: Treating adrenoleukodystrophy with Lorenzo's oil.J Biopharm Stat2016
27342435Chirally Pure Prodrugs and Their Converting Enzymes Lead to High Supersaturation and Rapid Transcellular Permeation of Benzodiazepines.J Pharm Sci2016
26836218A model-based approach to assess the exposure-response relationship of Lorenzo's oil in adrenoleukodystrophy.Br J Clin Pharmacol2016
25028414A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers.J Child Neurol2015
29443201Development of benzodiazepines for out-of-hospital management of seizure emergencies.Neurol Clin Pract2015
26603741Intravenous and Intramuscular Formulations of Antiseizure Drugs in the Treatment of Epilepsy.CNS Drugs2015
26670322Mechanisms of Antioxidant Induction with High-Dose N-Acetylcysteine in Childhood Cerebral Adrenoleukodystrophy.CNS Drugs2015
26052837Intravenous Administration of Stable-Labeled N-Acetylcysteine Demonstrates an Indirect Mechanism for Boosting Glutathione and Improving Redox Status.J Pharm Sci2015
26115606Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies.Epilepsy Behav2015
25912051Intravenous carbamazepine as short-term replacement therapy for oral carbamazepine in adults with epilepsy: Pooled tolerability results from two open-label trials.Epilepsia2015
25982590Bioequivalence of oral and intravenous carbamazepine formulations in adult patients with epilepsy.Epilepsia2015
25953073Canine status epilepticus treated with fosphenytoin: A proof of principle study.Epilepsia2015
25952988Use of IV fosphenytoin pharmacokinetics to determine the loading dose for a clinical trial of canine status epilepticus.Epilepsia2015
25403343Pharmacokinetic-pharmacodynamic modelling of intravenous and oral topiramate and its effect on phonemic fluency in adult healthy volunteers.Br J Clin Pharmacol2015
24697865Pharmacokinetics and pharmacodynamics of intravenous baclofen in dogs: a preliminary study.J Pharm Pharmacol2014
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Collaborators

University of Minnesota Twin Cities
Co-authored papers 31
Medical University of South Carolina
Co-authored papers 9
University of Michigan ann arbor
Co-authored papers 9
University of Virginia
Co-authored papers 9
University of California san francisco
Co-authored papers 7
Children's National Hospital Washington
Co-authored papers 7
Montefiore Medical Center, Albert Einstein College of Medicine
Co-authored papers 7
University of Minnesota
Co-authored papers 7
St. George's University Hospitals National Health Service Foundation Trust
Co-authored papers 6
Northwestern University Feinberg School of Medicine
Co-authored papers 6
University of Virginia Health Sciences Center
Co-authored papers 6
National Institute of Neurological Disorders and Stroke
Co-authored papers 4
School of Public Health, University of Minnesota
Co-authored papers 3
Albert Einstein College of Medicine
Co-authored papers 2
Monash University
Co-authored papers 2
Beth Israel Deaconess Medical Center, Division of Neurocritical Care and Emergency Neurology, Division of Clinical Neurophysiology, Massachusetts General Hospital, Boston, MA, Harvard Medical School, Massachusetts General Hospital, Massachusetts General Hospital Fellowship in Epilepsy and Clinical Neurophysiology, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School Fellowship Training Program in Neurocritical Care, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School Partners Neurology Residency Training Program, Yale College
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Cincinnati Children's Hospital Medical Center
Co-authored papers 2
University of Utah
Co-authored papers 1
Henry Ford Hospital
Co-authored papers 1
University of Pennsylvania, USA Hospital of the University of Pennsylvania
Co-authored papers 1
Medical College of Wisconsin
Co-authored papers 1
Co-authored papers 1
Downstate Health Sciences University
Co-authored papers 1
University of Texas, Southwestern Medical Center
Co-authored papers 1
Department of Pharmacy, 8Massachusetts General Hospital
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1
Department of Emergency Medicine Ohio State University Columbus Ohio USA.
Co-authored papers 1
Medical University of South Carolina
Co-authored papers 1
Cincinnati Children's Hospital Medical Center
Co-authored papers 1
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh.
Co-authored papers 1