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Author Details

Johanna M Seddon
University of Massachusetts Chan Medical School
1981
259
84
PMIDPaper TitleJournal TitlePublished Year
36701964Deep ensemble learning for automated non-advanced AMD classification using optimized retinal layer segmentation and SD-OCT scans.Comput Biol Med2023
37920864Evaluation of Risk Prediction with Hierarchical Data: Dependency Adjusted Confidence Intervals for the AUC.Stats (Basel)2023
37437830Family History of Age-Related Macular Degeneration and Genetics Predict Progression to Advanced Age-Related Macular Degeneration Adjusting for Macular Status, Demographic, and Lifestyle Factors.Am J Ophthalmol2023
36808601Blue Light Exposure: Ocular Hazards and Prevention-A Narrative Review.Ophthalmol Ther2023
36275200Identifying Novel Genes and Variants in Immune and Coagulation Pathways Associated with Macular Degeneration.Ophthalmol Sci2022
35749108A Screening Tool for Self-Evaluation of Risk for Age-Related Macular Degeneration: Validation in a Spanish Population.Transl Vis Sci Technol2022
36909148Rare Dysfunctional <i>Complement Factor I</i> Genetic Variants and Progression to Advanced Age-Related Macular Degeneration.Ophthalmol Sci2022
33473166Long-term risk of subsequent cancer incidence among hereditary and nonhereditary retinoblastoma survivors.Br J Cancer2021
33783477The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.Hum Mol Genet2021
33917779Benign Tumors in Long-Term Survivors of Retinoblastoma.Cancers (Basel)2021
34153328Increased Risk of Skin Cancer in 1,851 Long-Term Retinoblastoma Survivors.J Invest Dermatol2021
32407518Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size.Invest Ophthalmol Vis Sci2020
31987759Choriocapillaris dropout in early age-related macular degeneration.Exp Eye Res2020
33369641Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2020
33290288Eye Diseases Direct Interest to Complement Pathway and Macrophages as Regulators of Inflammation in COVID-19.Asia Pac J Ophthalmol (Phila)2020
32908800Functional Analysis of Rare Genetic Variants in Complement Factor I (<i>CFI</i>) using a Serum-Based Assay in Advanced Age-related Macular Degeneration.Transl Vis Sci Technol2020
30698734Patterns of Cause-Specific Mortality Among 2053 Survivors of Retinoblastoma, 1914-2016.J Natl Cancer Inst2019
31658355Association Between Perifoveal Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2019
31622129Bone and Soft-Tissue Sarcoma Risk in Long-Term Survivors of Hereditary Retinoblastoma Treated With Radiation.J Clin Oncol2019
30389371Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High-Risk Individuals.Am J Ophthalmol2019
30242352Progress in Automated Deep Learning for Macular Degeneration.JAMA Ophthalmol2018
28892825Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2017
29027953Vitamin D and Age-Related Macular Degeneration.Nutrients2017
29288272Macular Degeneration Epidemiology: Nature-Nurture, Lifestyle Factors, Genetic Risk, and Gene-Environment Interactions - The Weisenfeld Award Lecture.Invest Ophthalmol Vis Sci2017
28859197Rare Genetic Variants in Age-Related Macular Degeneration.JAMA Ophthalmol2017
28715590Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2017
26220834Idiopathic preretinal glia in aging and age-related macular degeneration.Exp Eye Res2016
28011711Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degenerationâ¿ .Hum Mol Genet2016
27657855Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration.JAMA Ophthalmol2016
27802514Distribution and Quantification of Choroidal Macrophages in Human Eyes With Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2016
27471039Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis.Br J Ophthalmol2016
27572114Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD.Sci Rep2016
27548457Diagnosis and Follow-Up of Nonexudative Choroidal Neovascularization With Multiple Optical Coherence Tomography Angiography Devices: A Case Report.Ophthalmic Surg Lasers Imaging Retina2016
27459452Contribution of the Nurses' Health Study to the Epidemiology of Cataract, Age-Related Macular Degeneration, and Glaucoma.Am J Public Health2016
26961928Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study.Am J Clin Nutr2016
26931413Increased choroidal mast cells and their degranulation in age-related macular degeneration.Br J Ophthalmol2016
26878444Analysis of Choroidal and Retinal Vasculature in Inherited Retinal Degenerations Using Optical Coherence Tomography Angiography.Ophthalmic Surg Lasers Imaging Retina2016
26705092Predictors of Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment of Age-Related Macular Degeneration.Am J Ophthalmol2016
25788521Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels.Hum Mol Genet2015
26490493Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study.Am J Clin Nutr2015
26501415Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration.Invest Ophthalmol Vis Sci2015
25880396Phenotypic Characterization of Complement Factor H R1210C Rare Genetic Variant in Age-Related Macular Degeneration.JAMA Ophthalmol2015
25655794Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates.Invest Ophthalmol Vis Sci2015
24498017Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.PLoS One2014
25034031Genetic variants in the complement system predisposing to age-related macular degeneration: a review.Mol Immunol2014
25033836(Epi)Genetic analyses of age-related macular degeneration: case-control and discordant twin studies.Hum Hered2014
25185089Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.J Clin Oncol2014
24847005Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.Hum Mol Genet2014
24755883Breast cancer risk after radiotherapy for heritable and non-heritable retinoblastoma: a US-UK study.Br J Cancer2014
24911414Allele-specific methylation occurs at genetic variants associated with complex disease.PLoS One2014
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Collaborators

Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 46
Tufts University School of Medicine and Tufts Medical Center
Co-authored papers 31
Massachusetts General Hospital
Co-authored papers 23
Tufts Medical Center
Co-authored papers 19
Harvard T. H. Chan School of Public Health
Co-authored papers 17
Co-authored papers 16
Center for Human Genetic Research, Massachusetts General Hospital
Co-authored papers 16
National Cancer Institute
Co-authored papers 15
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 12
Casey Eye Institute, Oregon Health & Science University
Co-authored papers 12
Columbia University Medical Center
Co-authored papers 10
University of Paris Est-Creteil
Co-authored papers 10
Massachusetts Eye and Ear Infirmary
Co-authored papers 10
National Eye Institute, National Institutes of Health
Co-authored papers 9
Washington University School of Medicine
Co-authored papers 9
Brigham and Women's Hospital
Co-authored papers 8
University of Wisconsin School of Medicine and Public Health
Co-authored papers 8
University of Utah
Co-authored papers 8
Northwestern University
Co-authored papers 7
National Eye Institute, National Institutes of Health
Co-authored papers 7
Erasmus Medical Center
Co-authored papers 7
Harvard University, Harvard Medical School
Co-authored papers 7
Center for Human Disease Modeling, Duke University School of Medicine
Co-authored papers 6
Johns Hopkins University School of Medicine
Co-authored papers 6
The Wilmer Eye Institute, Johns Hopkins University School of Medicine
Co-authored papers 6
National Eye Institute, National Institutes of Health
Co-authored papers 6
Regeneron Pharmaceuticals Inc.
Co-authored papers 6
Jules Stein Eye Institute
Co-authored papers 6
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 6
The University of Melbourne
Co-authored papers 5