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Author Details

Dennis C Sgroi
1986
162
75
PMIDPaper TitleJournal TitlePublished Year
35144966Breast Cancer Index Is a Predictive Biomarker of Treatment Benefit and Outcome from Extended Tamoxifen Therapy: Final Analysis of the Trans-aTTom Study.Clin Cancer Res2022
36527133Correlative studies of the Breast Cancer Index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine therapy benefit: a Trans-aTTom study.Breast Cancer Res2022
35218378Is Real-Time Microscopy on the Horizon? A Brief Review of the Potential Future Directions in Clinical Breast Tumor Microscopy Implementation.Virchows Archiv2022
34376532Prognostic Utility of Breast Cancer Index to Stratify Distant Recurrence Risk in Invasive Lobular Carcinoma.Clinical Cancer Research2021
34144976CD8<sup>+</sup> T cell immunity blocks the metastasis of carcinogen-exposed breast cancer.Sci Adv2021
31371343<i>FGFR1</i> Amplification Mediates Endocrine Resistance but Retains TORC Sensitivity in Metastatic Hormone Receptor-Positive (HR<sup>+</sup>) Breast Cancer.Clin Cancer Res2019
30350269Discrepancy in risk assessment of hormone receptor positive early-stage breast cancer patients using breast cancer index and recurrence score.Breast Cancer Res Treat2019
31031007Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.Cell2019
30911675AKT1<sup>low</sup> quiescent cancer cells in ductal carcinoma in situ of the breast.NPJ Breast Cancer2019
29453314AR Expression in Breast Cancer CTCs Associates with Bone Metastases.Mol Cancer Res2018
29054988AKT1<sup>low</sup> Quiescent Cancer Cells Promote Solid Tumor Growth.Mol Cancer Ther2018
29450494Comparison of the Performance of 6 Prognostic Signatures for Estrogen Receptor-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial.JAMA Oncol2018
29242214Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer.Cancer Discov2018
28096337Stress granule-associated protein G3BP2 regulates breast tumor initiation.Proc Natl Acad Sci U S A2017
28764807AKT1<sup>low</sup> quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer.Breast Cancer Res2017
28939745A Novel Breast Cancer Index for Prediction of Distant Recurrence in HR Early-Stage Breast Cancer with One to Three Positive Nodes.Clinical Cancer Research2017
28485815Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing.Cancer2017
28795152Risk stratification with Breast Cancer Index for late distant recurrence in patients with clinically low-risk (T1N0) estrogen receptor-positive breast cancer.npj Breast Cancer2017
28252345Evidence of stress in β cells obtained with laser capture microdissection from pancreases of brain dead donors.Islets2017
27551134Biomarkers for Early-Stage Breast Cancer: Clinical Utility for Extended Adjuvant Treatment Decisions.Journal of Clinical Oncology2016
27096583CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 12-2016. An 8-Year-Old Boy with an Enlarging Mass in the Right Breast.New England Journal of Medicine2016
27323815The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.Oncotarget2016
26728744Assessment of the prognostic and predictive utility of the Breast Cancer Index (BCI): an NCIC CTG MA.14 study.Breast Cancer Res2016
27252417Cross-Stratification and Differential Risk by Breast Cancer Index and Recurrence Score in Women with Hormone Receptor-Positive Lymph Node-Negative Early-Stage Breast Cancer.Clinical Cancer Research2016
27116182Relapse-free survival of statistically standardized continuous RT-PCR estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2): NCIC CTG MA.14.Breast Cancer Res Treat2016
27758885Alternative Polyadenylation in Triple-Negative Breast Tumors Allows NRAS and c-JUN to Bypass PUMILIO Posttranscriptional Regulation.Cancer Research2016
27556950HER2 expression identifies dynamic functional states within circulating breast cancer cells.Nature2016
26479444Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis.Oncogenesis2015
25409150Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.Nature2015
24886537VAV3 mediates resistance to breast cancer endocrine therapy.Breast Cancer Res2014
25489927Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.Nature Communications2014
25521819Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas.BMC Medical Genomics2014
25427824Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1.BMC Cancer2014
24346130Eight-year update of a prospective study of wide excision alone for small low- or intermediate-grade ductal carcinoma in situ (DCIS).Breast Cancer Research and Treatment2014
24715381Lack of G protein-coupled estrogen receptor (GPER) in the plasma membrane is associated with excellent long-term prognosis in breast cancer.Breast Cancer Res Treat2014
24625110A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.Breast Cancer Res2014
25013076Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.Science2014
23497539HOXB13:IL17BR and molecular grade index and risk of breast cancer death among patients with lymph node-negative invasive disease.Breast Cancer Research2013
24035531Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.Lancet Oncology, The2013
23812955Prediction of late disease recurrence and extended adjuvant letrozole benefit by the HOXB13/IL17BR biomarker.J Natl Cancer Inst2013
23757354Breast cancer index identifies early-stage estrogen receptor-positive breast cancer patients at risk for early- and late-distant recurrence.Clinical Cancer Research2013
23755103Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A.PLoS One2013
24131622The mTOR effectors 4EBP1 and S6K2 are frequently coexpressed, and associated with a poor prognosis and endocrine resistance in breast cancer: a retrospective study including patients from the randomised Stockholm tamoxifen trials.Breast Cancer Research2013
23670096Oestrogen receptor co-activator AIB1 is a marker of tamoxifen benefit in postmenopausal breast cancer.Annals of Oncology2013
23628188Planning cancer control in Latin America and the Caribbean.Lancet Oncol2013
23372014Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition.Science2013
21690342The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway.Proceedings of the National Academy of Sciences of the United States of America2012
22722202Sequence analysis of mutations and translocations across breast cancer subtypes.Nature2012
23104009Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.Nat Genet2012
22240506Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse.Molecular and Cellular Proteomics2012
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Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School
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National Human Genome Research Institute
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German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT)
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