Author details

Full Name

Markus G GrÃ¼tter

Affiliation

ORCID

Career Start Year

1974

Papers

193

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36787260	NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.		2023
29237846	The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5Î±.	Journal of Virology	2018
28824717	Non-invasive <i>in vivo</i> imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin.	Theranostics	2017
27801679	NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.	Journal of Clinical Investigation	2016
26894544	Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects.	Acta Crystallographica Section D: Structural Biology	2016
27043286	NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.	Journal of Clinical Investigation	2016
26043233	Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomers.	Scientific Reports	2015
25947941	A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.	Biochemistry	2015
26275827	Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins.	J Cell Sci	2015
24779913	Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise.	Biochemical Journal	2014
28982439	Biocrystallography in Switzerland: Achievements and Future Perspectives.	Chimia	2014
24815518	Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase recruitment domain.	Biochemistry	2014
25030449	Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.	Proceedings of the National Academy of Sciences of the United States of America	2014
24801698	Biocrystallography in Switzerland: achievements and future perspectives.	Chimia	2014
25153593	Specific targeting of human caspases using designed ankyrin repeat proteins.	Biological Chemistry	2014
23333429	Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors.	Structure	2013
23868333	Design, construction, and characterization of a second-generation DARP in library with reduced hydrophobicity.	Protein Science	2013
23810698	Structure and substrate-induced conformational changes of the secondary citrate/sodium symporter CitS revealed by electron crystallography.	Structure	2013
24325597	Chimeric hERG channels containing a tetramerization domain are functional and stable.	Biochemistry	2013
24132235	Precision is essential for efficient catalysis in an evolved Kemp eliminase.	Nature	2013
23277102	Generation of an antibody toolbox to characterize hERG.	Biochemical and Biophysical Research Communications	2013
23431166	Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.	Proceedings of the National Academy of Sciences of the United States of America	2013
23546876	The structure of Bradyrhizobium japonicum transcription factor FixK2 unveils sites of DNA binding and oxidation.	Journal of Biological Chemistry	2013
23578532	New concepts and aids to facilitate crystallization.	Current Opinion in Structural Biology	2013
22261618	A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.	Cell Death and Differentiation	2012
28978392	X-Ray Structure of a Heterodimeric ABC Transporter Crystallized in its Inward-Facing Conformation.	Chimia	2012
22349493	Projection structure of the secondary citrate/sodium symporter CitS at 6 Ã¿ resolution by electron crystallography.	J Mol Biol	2012
22544642	Structure-based optimization of designed Armadillo-repeat proteins.	Protein Science	2012
22961926	Crystal structures of BapA complexes with Î²-lactam-derived inhibitors illustrate substrate specificity and enantioselectivity of Î²-aminopeptidases.	ChemBioChem	2012
22683476	Human caspases in vitro: expression, purification and kinetic characterization.	Protein Expression and Purification	2012
22772153	Quality control of disulfide bond formation in pilus subunits by the chaperone FimC.	Nature Chemical Biology	2012
22675494	Tuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin binders.	PLoS ONE	2012
22523072	Asymmetry in the homodimeric ABC transporter MsbA recognized by a DARPin.	Journal of Biological Chemistry	2012
22451937	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop.	Proceedings of the National Academy of Sciences of the United States of America	2012
22482711	TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling.	Current Opinion in Virology	2012
22447242	Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation.	Nature Structural and Molecular Biology	2012
22980995	Autoproteolytic and catalytic mechanisms for the Î²-aminopeptidase BapA--a member of the Ntn hydrolase family.	Structure	2012
21821879	In silico identification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moiety.		2011
21256010	HIV-1 protease inhibition potential of functionalized polyoxometalates.	Bioorganic and Medicinal Chemistry Letters	2011
21075107	Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy.	FEBS Letters	2011
21296164	Designed ankyrin repeat protein binders for the crystallization of AcrB: plasticity of the dominant interface.	Journal of Structural Biology	2011
21512573	TRIM5 is an innate immune sensor for the retrovirus capsid lattice.	Nature	2011
21710479	PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism.	Protein Science	2011
21829623	A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders.	PLoS ONE	2011
20229565	Isolation of a small-molecule inhibitor of the antiapoptotic protein Bcl-xL from a DNA-encoded chemical library.	ChemMedChem	2010
20851349	Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe.		2010
20851127	Structural determinants for improved stability of designed ankyrin repeat proteins with a redesigned C-capping module.	Journal of Molecular Biology	2010
20696404	Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism.	Structure	2010
19851329	Studies of the molecular mechanism of caspase-8 activation by solution NMR.	Cell Death and Differentiation	2010
20357830	Generation of human TRIM5alpha mutants with high HIV-1 restriction activity.	Gene Therapy	2010