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Author Details

Poul H Sorensen
British Columbia Cancer Research Centre
1989
214
72
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36761762Human antibodies targeting ENPP1 as candidate therapeutics for cancers.Front Immunol2023
37774704Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.Cell Rep Med2023
37611092A MYCN-independent mechanism mediating secretome reprogramming and metastasis in <i>MYCN</i>-amplified neuroblastoma.Sci Adv2023
37279093A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma.Clin Cancer Res2023
36761762Human antibodies targeting ENPP1 as candidate therapeutics for cancers.Front Immunol2023
37232837Pediatric Brain Tumours: Lessons from the Immune Microenvironment.Curr Oncol2023
37611092A MYCN-independent mechanism mediating secretome reprogramming and metastasis in <i>MYCN</i>-amplified neuroblastoma.Sci Adv2023
37774704Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma.Cell Rep Med2023
37279093A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma.Clin Cancer Res2023
37232837Pediatric Brain Tumours: Lessons from the Immune Microenvironment.Curr Oncol2023
34294889De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer.Cell Death Differ2022
36229487Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division.Nat Commun2022
36167467Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.J Immunother Cancer2022
35365367Transsulfuration, minor player or crucial for cysteine homeostasis in cancer.Trends Cell Biol2022
36131014Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
35672300Author Correction: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.Nat Commun2022
36446943Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
34294889De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer.Cell Death Differ2022
33908607MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress.Blood2022
34971569GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.Cancer Cell2022
35027753Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication.Nat Med2022
35139387Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.Cell Rep2022
34702771Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study.Clin Cancer Res2022
34939643Regulation of AR mRNA translation in response to acute AR pathway inhibition.Nucleic Acids Res2022
35197518Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells.Sci Rep2022
35672300Author Correction: The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.Nat Commun2022
35365367Transsulfuration, minor player or crucial for cysteine homeostasis in cancer.Trends Cell Biol2022
36446943Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36131014Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36229487Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division.Nat Commun2022
36167467Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.J Immunother Cancer2022
33908607MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress.Blood2022
34939643Regulation of AR mRNA translation in response to acute AR pathway inhibition.Nucleic Acids Res2022
34971569GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity.Cancer Cell2022
35027753Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication.Nat Med2022
35139387Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells.Cell Rep2022
35197518Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells.Sci Rep2022
34702771Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study.Clin Cancer Res2022
33435412Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Pediatric Patients.Curr Oncol2021
34021002Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.Cancer Discov2021
33691136Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery.Immunity2021
34045740Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma.Nat Med2021
33828989NSG Mice Facilitate <i>ex vivo</i> Characterization of Ewing Sarcoma Lung Metastasis Using the PuMA Model.Front Oncol2021
34092244α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.Acta Neuropathol Commun2021
33603169HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.Oncogene2021
33709547Androgen receptor (AR) antagonism triggers acute succinate-mediated adaptive responses to reactivate AR signaling.EMBO Mol Med2021
33435412Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Pediatric Patients.Curr Oncol2021
34440851Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function.Cells2021
34778803NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity.Blood Cancer Discov2021
34604225Extracellular Vesicles in Reprogramming of the Ewing Sarcoma Tumor Microenvironment.Front Cell Dev Biol2021
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Collaborators

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Co-authored papers 16
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McGill University Health Centre (MUHC), Montreal Children's Hospital (MCH)
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Seattle Children's Research Institute
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Hospital for Sick Children
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Center for Cancer Research
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The Hospital for Sick Children
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University of Wollongong
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The Research Institute of the McGill University Health Centre, McGill University
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The Hospital for Sick Children, University of Toronto
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Sanford Burnham Prebys Medical Discovery Institute
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Hopp Children's Cancer Center Heidelberg (KiTZ)
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University of California san francisco
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Technische Universitat Munchen
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University of British Columbia
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