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Author Details

Elizabeth A Heller
University of Pennsylvania
2003
45
22
PMIDPaper TitleJournal TitlePublished Year
36906500Cell Type-Specific Whole-Genome Landscape of οFOSB Binding in the Nucleus Accumbens After Chronic Cocaine Exposure.Biol Psychiatry2023
37577575MousiPLIER: A Mouse Pathway-Level Information Extractor Model.bioRxiv2023
37149717Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching.Nat Commun2023
37433783Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.Nat Commun2023
36813830Author Correction: Cell-type specific profiling of histone post-translational modifications in the adult mouse striatum.Nat Commun2023
36849418Tip60's Novel RNA-Binding Function Modulates Alternative Splicing of Pre-mRNA Targets Implicated in Alzheimer's Disease.J Neurosci2023
36842544Early life adversity: Epigenetic regulation underlying drug addiction susceptibility.Mol Cell Neurosci2023
36130958Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice.Sci Rep2022
36280459Convergent actions of stress and stimulants via epigenetic regulation of neural circuitry.Trends Neurosci2022
33325096Adolescent oxycodone exposure inhibits withdrawal-induced expression of genes associated with the dopamine transmission.Addict Biol2021
34480866Chromatin-mediated alternative splicing regulates cocaine-reward behavior.Neuron2021
32319526Specific histone modifications associate with alternative exon selection during mammalian development.Nucleic Acids Res2020
31980629Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes.Nat Commun2020
32600739Stress Regulation of Sustained Attention and the Cholinergic Attention System.Biol Psychiatry2020
30661667Sex-Specific Regulation of Fear Memory by Targeted Epigenetic Editing of Cdk5.Biol Psychiatry2019
31477569Epigenetic Regulation of Hippocampal <i>Fosb</i> Expression Controls Behavioral Responses to Cocaine.J Neurosci2019
31619487Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions.J Neurosci2019
31015104Recent advances in neuroepigenetic editing.Curr Opin Neurobiol2019
30552390A novel role for E2F3b in regulating cocaine action in the prefrontal cortex.Neuropsychopharmacology2019
29453446Environmental, genetic and epigenetic contributions to cocaine addiction.Neuropsychopharmacology2018
29891732Cell-Type-Specific Role of οFosB in Nucleus Accumbens In Modulating Intermale Aggression.J Neurosci2018
30155827Stereotaxic Surgery and Viral Delivery of Zinc-Finger Epigenetic Editing Tools in Rodent Brain.Methods Mol Biol2018
30031009Single sample sequencing (S3EQ) of epigenome and transcriptome in nucleus accumbens.J Neurosci Methods2018
28462942Cell-Type-Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress.Neuropsychopharmacology2018
29524136Viral Expression of Epigenome Editing Tools in Rodent Brain Using Stereotaxic Surgery Techniques.Methods Mol Biol2018
29524131Neuroepigenetic Editing.Methods Mol Biol2018
29397901Transcription Factor E2F3a in Nucleus Accumbens Affects Cocaine Action via Transcription and Alternative Splicing.Biol Psychiatry2018
27569543Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles.Biol Psychiatry2017
28530238MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.Nat Commun2017
28609483Histone posttranslational modifications predict specific alternative exon subtypes in mammalian brain.PLoS Comput Biol2017
26844834Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling.Neuron2016
27122028Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior.J Neurosci2016
27181059Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility.Neuron2016
25099208Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area.J Neurochem2015
26390241ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior.Nat Med2015
25698746SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens.J Neurosci2015
25486626Regulation of chromatin states by drugs of abuse.Curr Opin Neurobiol2015
24270188Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway.Nat Neurosci2014
25347353Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors.Nat Neurosci2014
25143625Threonine 149 phosphorylation enhances οFosB transcriptional activity to control psychomotor responses to cocaine.J Neurosci2014
24853771Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition.Neuropsychopharmacology2014
24107942Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action.J Neurosci2013
22768092The biochemical anatomy of cortical inhibitory synapses.PLoS One2012
19402746Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse.PLoS Biol2009
12773581Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning.Learn Mem2003
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Collaborators

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College of Basic Medical Sciences, Army Medical University
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Douglas Institute, McGill University
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Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 2
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
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HHMI/NYU Langone School of Medicine
Co-authored papers 1
The Rockefeller University
Co-authored papers 1
Max Plank Institute for Psychiatry.
Co-authored papers 1
University of Manchester
Co-authored papers 1
Co-authored papers 1
Graduate School of Medicine, The University of Tokyo
Co-authored papers 1
University of California los angeles
Co-authored papers 1
University of Pennsylvania
Co-authored papers 1
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Guy's and St Thomas' NHS Foundation Trust
Co-authored papers 1
University of Pennsylvania
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