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Author Details
Full Name
Kathy K Niakan
Affiliation
The Francis Crick Institute
ORCID
Career Start Year
2000
Papers
47
H Index
28
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37295962
Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1.
Hum Reprod
2023
38012405
Author Correction: Changing the public perception of human embryology.
Nat Cell Biol
2023
37619506
Human embryo models: the importance of national policy and governance review.
Curr Opin Genet Dev
2023
37985870
Changing the public perception of human embryology.
Nat Cell Biol
2023
37879938
MICA: a multi-omics method to predict gene regulatory networks in early human embryos.
Life Sci Alliance
2023
36971487
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals.
Development
2023
35502739
GIANI - open-source software for automated analysis of 3D microscopy images.
J Cell Sci
2022
33239783
TRF2-independent chromosome end protection during pluripotency.
Nature
2021
34432381
Generating CRISPR-Cas9-Mediated Null Mutations and Screening Targeting Efficiency in Human Pluripotent Stem Cells.
Curr Protoc
2021
34463252
TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells.
Elife
2021
34050011
Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos.
Proc Natl Acad Sci U S A
2021
34048692
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.
Stem Cell Reports
2021
34048690
Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines.
Stem Cell Reports
2021
32451402
The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes.
Nat Commun
2020
31778245
Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos.
Stem Cells
2020
31822824
Author Correction: Human germline genome editing.
Nat Cell Biol
2020
32034154
IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche.
Nat Commun
2020
32968278
Initiation of a conserved trophectoderm program in human, cow and mouse embryos.
Nature
2020
33021826
Human Embryogenesis: A Comparative Perspective.
Annu Rev Cell Dev Biol
2020
29477167
Human Pre-gastrulation Development.
Curr Top Dev Biol
2018
30393076
SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.
Dev Cell
2018
28976971
Erratum: Genome editing reveals a role for OCT4 in human embryogenesis.
Nature
2017
28087629
Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.
Development
2017
29107595
Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development.
Stem Cell Reports
2017
28953884
Genome editing reveals a role for OCT4 in human embryogenesis.
Nature
2017
27281217
Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.
Nature
2016
27144686
Self-organization of the human embryo in the absence of maternal tissues.
Nat Cell Biol
2016
27462813
Corrigendum: Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.
Nature
2016
26109048
Gata6 potently initiates reprograming of pluripotent and differentiated cells to extraembryonic endoderm stem cells.
Genes Dev
2015
26487783
Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.
Development
2015
26293300
Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.
Development
2015
26059426
Dynamic Proteomic Profiling of Extra-Embryonic Endoderm Differentiation in Mouse Embryonic Stem Cells.
Stem Cells
2015
23261930
Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse.
Dev Biol
2013
23640167
Derivation of extraembryonic endoderm stem (XEN) cells from mouse embryos and embryonic stem cells.
Nat Protoc
2013
22318624
Human pre-implantation embryo development.
Development
2012
22802932
Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status.
PLoS One
2012
22791892
Conversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states.
Development
2012
21816365
BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages.
Cell Stem Cell
2011
20123909
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.
Genes Dev
2010
19200798
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Cell Stem Cell
2009
18669821
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons.
Science
2008
16466956
Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis.
Mol Genet Metab
2006
16146703
DAX1 origin, function, and novel role.
Mol Genet Metab
2005
14678822
Nr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesis.
Gene Expr Patterns
2004
15300857
IL1RAPL1 is associated with mental retardation in patients with complex glycerol kinase deficiency who have deletions extending telomeric of DAX1.
Hum Mutat
2004
12200364
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction.
Blood
2002
10733494
Mapping of a syndrome of X-linked thrombocytopenia with Thalassemia to band Xp11-12: further evidence of genetic heterogeneity of X-linked thrombocytopenia.
Blood
2000
1 - 47 of 47
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