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Author Details

Marc Vidal
Blavatnik Institute, Harvard Medical School
1989
246
104
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37061542Next-generation large-scale binary protein interaction network for Drosophila melanogaster.Nat Commun2023
35662469OpenPIP: An Open-source Platform for Hosting, Visualizing and Analyzing Protein Interaction Data.J Mol Biol2022
35654359New Views of Old Proteins: Clarifying the Enigmatic Proteome.Mol Cell Proteomics2022
33257861A comprehensive library of human transcription factors for cell fate engineering.Nat Biotechnol2021
33558758Comprehensive characterization of protein-protein interactions perturbed by disease mutations.Nat Genet2021
34543356The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.PLoS Pathog2021
33962942Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells.Sci Adv2021
32393825ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms.Nat Commun2020
33060198Interrogation of kinase genetic interactions provides a global view of PAK1-mediated signal transduction pathways.J Biol Chem2020
32392905Yeast-Based Genetic Interaction Analysis of Human Kinome.Cells2020
32296183A reference map of the human binary protein interactome.Nature2020
32199228Precision medicine - networks to the rescue.Curr Opin Biotechnol2020
32398372A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice.Proc Natl Acad Sci U S A2020
30886144Network-based prediction of protein interactions.Nat Commun2019
31467278Maximizing binary interactome mapping with a minimal number of assays.Nat Commun2019
31375661A genome-wide positioning systems network algorithm for in silico drug repurposing.Nat Commun2019
31315049Global Analysis of Intercellular Homeodomain Protein Transfer.Cell Rep2019
30715274APID database: redefining protein-protein interaction experimental evidences and binary interactomes.Database (Oxford)2019
29426014Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes.J Mol Biol2018
29855947Protein Interactomics by Two-Hybrid Methods.Methods Mol Biol2018
29977601Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.NPJ Syst Biol Appl2018
29443976How many human proteoforms are there?Nat Chem Biol2018
28575653Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits.Am J Hum Genet2017
28131822Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.Cell Syst2017
28131823In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.Cell Syst2017
28215707HSP90 Shapes the Consequences of Human Genetic Variation.Cell2017
28285768Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits.Am J Hum Genet2017
28284537Proteome-Scale Human Interactomics.Trends Biochem Sci2017
29220033Challenges and recommendations for epigenomics in precision health.Nat Biotechnol2017
29269382A framework for exhaustively mapping functional missense variants.Mol Syst Biol2017
28542158Identifying pathogenicity of human variants via paralog-based yeast complementation.PLoS Genet2017
28596290Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target.Genome Res2017
28846689Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing.PLoS Comput Biol2017
28575754Mapping, modeling, and characterization of protein-protein interactions on a proteomic scale.Curr Opin Struct Biol2017
26871637Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.Cell2016
26546296MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy.Cancer Discov2016
27803151Proteome-scale Binary Interactomics in Human Cells.Mol Cell Proteomics2016
27273514The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.Nat Struct Mol Biol2016
27565335Playing Hide-and-Seek with Yeast.Cell2016
27357687Mapping transcription factor interactome networks using HaloTag protein arrays.Proc Natl Acad Sci U S A2016
27165778How much of the human protein interactome remains to be mapped?Sci Signal2016
26889812A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States.Neuron2016
26831545Network-based in silico drug efficacy screening.Nat Commun2016
27013732Survey of variation in human transcription factors reveals prevalent DNA binding changes.Science2016
27107014An inter-species protein-protein interaction network across vast evolutionary distance.Mol Syst Biol2016
27107012Pooled-matrix protein interaction screens using Barcode Fusion Genetics.Mol Syst Biol2016
26975778An extended set of yeast-based functional assays accurately identifies human disease mutations.Genome Res2016
25532137Selecting causal genes from genome-wide association studies via functionally coherent subnetworks.Nat Methods2015
27136053Global Edgetic Rewiring in Cancer Networks.Cell Syst2015
25910212Widespread macromolecular interaction perturbations in human genetic disorders.Cell2015
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Collaborators

Frederick P Roth
University of Toronto
Co-authored papers 37
Albert-L??szl?? Barab??si
Network Science Institute, Northeastern University
Co-authored papers 17
Nicolas Bertin
University Bordeaux, CNRS
Co-authored papers 15
Nidhi Sahni
The University of Texas MD Anderson Cancer Center
Co-authored papers 14
Haiyuan Yu
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 13
Nicolas Simonis
Co-authored papers 13
Kavitha Venkatesan
Co-authored papers 12
Song Yi
Livestrong Cancer Institutes, Dell Medical School, The University of Texas at Austin
Co-authored papers 11
Charles Boone
University of Toronto
Co-authored papers 10
Anne-Ruxandra Carvunis
University of Pittsburgh School of Medicine.
Co-authored papers 10
Simon J Boulton
The Francis Crick Institute
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Chenwei Lin
Clinical Research Division, Fred Hutchinson Cancer Center
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Kristin C Gunsalus
Center for Genomics and Systems Biology, New York University Abu Dhabi (NYUAD)
Co-authored papers 9
Dong Han
Beijing University of Chinese Medicine
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Yu Xia
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Gary D Bader
University of Toronto
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Muneesh Tewari
University of Michigan ann arbor
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Joseph R Ecker
The Salk Institute for Biological Studies
Co-authored papers 7
Susan Lindquist
Whitehead Institute for Biomedical Research
Co-authored papers 6
Kerstin Spirohn
Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute
Co-authored papers 6
Patrick Aloy
Institucio Catalana de Recerca i Estudis Avancats (ICREA)
Co-authored papers 6
J??rg Menche
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 6
Mark Gerstein
Yale University
Co-authored papers 5
Xiaofeng Xin
Massachusetts Institute of Technology
Co-authored papers 5
Debra S Goldberg
University of Colorado at Boulder
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Javier De Las Rivas
Cancer Research Centre (IBMCC/CSIC/USAL/IBSAL)
Co-authored papers 5
Nozomu Yachie
The University of British Columbia
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Lan V Zhang
Harvard Medical School
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Gianni Cesareni
University of Rome 'Tor Vergata'
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Release 1.2