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Author Details

Ivan Marazzi
Center for Epigenetics and Metabolism, University of California irvine
2004
33
19
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37339625Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics.Cell Host Microbe2023
37903791Isoform-resolved transcriptome of the human preimplantation embryo.Nat Commun2023
37995687Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation.Mol Cell2023
37537299WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma.Nat Cancer2023
37090613The anti-cancer compound JTE-607 reveals hidden sequence specificity of the mRNA 3' processing machinery.bioRxiv2023
37214953Leveraging inter-individual transcriptional correlation structure to infer discrete signaling mechanisms across metabolic tissues.bioRxiv2023
35945277Author Correction: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4.Nature2022
35697804Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR.Nat Biotechnol2022
34012080Unconventional viral gene expression mechanisms as therapeutic targets.Nature2021
33836156TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.Cell2021
34587491Emergency drug use in a pandemic: Harsh lessons from COVID-19.Cell2021
34478653A small nucleosome from a weird virus with a fat genome.Mol Cell2021
33970190DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells.J Exp Med2021
34075878HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.Elife2021
32649876Human Virus Transcriptional Regulators.Cell2020
32084337A Quantitative Genetic Interaction Map of HIV Infection.Mol Cell2020
33299999Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.bioRxiv2020
29184195Chromatin dependencies in cancer and inflammation.Nat Rev Mol Cell Biol2018
30177761Influenza virus infection causes global RNAPII termination defects.Nat Struct Mol Biol2018
30146161Transcription Elongation Can Affect Genome 3D Structure.Cell2018
30413362Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance.Immunity2018
28475896The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.Cell2017
26789921Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.Immunity2016
27127234Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.Science2016
25822250Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis.Nat Immunol2015
26232586Interference of viral effector proteins with chromatin, transcription, and the epigenome.Curr Opin Microbiol2015
26205286Editorial overview: host-microbe interactions: viruses.Curr Opin Microbiol2015
22419161Suppression of the antiviral response by an influenza histone mimic.Nature2012
21068722Suppression of inflammation by a synthetic histone mimic.Nature2010
17707231Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly.Mol Cell2007
16467852A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity.EMBO J2006
15843800Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time.Nat Immunol2005
15226358Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response.J Exp Med2004
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University of Cincinnati College of Medicine
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The Rockefeller University
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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Universite de Toulon, CNRS
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Icahn School of Medicine at Mount Sinai
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Northwestern University Feinberg School of Medicine
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The Scripps Research Institute
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