Author details

Full Name

Paul C Sternweis

Affiliation

ORCID

Career Start Year

1974

Papers

106

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
29196061	Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.	J Struct Biol	2018
29876405	Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase.	Data in Brief	2018
26627240	Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.	Proc Natl Acad Sci U S A	2015
24855647	Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).	Journal of Biological Chemistry	2014
23178822	Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation.	Molecular Immunology	2013
23493395	Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins.	Journal of Biological Chemistry	2013
23229509	Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway.	Molecular Pharmacology	2013
22661716	Activation of p115-RhoGEF requires direct association of GÎ±13 and the Dbl homology domain.	Journal of Biological Chemistry	2012
21064165	Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF.	Protein Science	2011
20505140	Distinct roles of adenylyl cyclase VII in regulating the immune responses in mice.	Journal of Immunology	2010
20430886	Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.	Journal of Biological Chemistry	2010
19883664	Modeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage.	Journal of Theoretical Biology	2010
19454649	Deciphering signaling outcomes from a system of complex networks.	Sci Signal	2009
19531803	Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105.	Science Signaling	2009
18541530	Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII.	Journal of Biological Chemistry	2008
18940608	Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.	Structure	2008
18411281	Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium.	Journal of Biological Chemistry	2008
17283075	Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway.	Journal of Biological Chemistry	2007
17854659	Regulation of Rho guanine nucleotide exchange factors by G proteins.		2007
16699502	A global analysis of cross-talk in a mammalian cellular signalling network.	Nature Cell Biology	2006
15665872	Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.	Nature Structural and Molecular Biology	2005
15143072	Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells.	Journal of Biological Chemistry	2004
15313570	Ribozyme- and siRNA-mediated suppression of RGS-containing RhoGEF proteins.	Methods in Enzymology	2004
15585835	Analysis of the major patterns of B cell gene expression changes in response to short-term stimulation with 33 single ligands.	J Immunol	2004
14581471	RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.	Journal of Biological Chemistry	2004
12525488	Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF.	Journal of Biological Chemistry	2003
11665616	Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D.	Methods in Enzymology	2002
11698392	Mechanisms for reversible regulation between G13 and Rho exchange factors.	Journal of Biological Chemistry	2002
12478301	Overview of the Alliance for Cellular Signaling.	Nature	2002
12115726	p115 Rho GTPase activating protein interacts with MEKK1.	Journal of Cellular Physiology	2002
11665621	Functional characterization of p115 RhoGEF.	Methods in Enzymology	2002
11242047	Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins.	Nature	2001
11524686	Structure of the rgRGS domain of p115RhoGEF.		2001
11384980	Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor.	Journal of Biological Chemistry	2001
11083860	The C terminus of mammalian phospholipase D is required for catalytic activity.	Journal of Biological Chemistry	2001
10329682	The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae.	J Biol Chem	1999
9641915	p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.	Science	1998
9770489	Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects.	Proc Natl Acad Sci U S A	1998
9641916	Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.	Science	1998
9151726	The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin.	Journal of Neuroscience	1997
9261058	The role of lipid signaling in constitutive membrane traffic.	Current Opinion in Cell Biology	1997
9242915	Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D.	Annual Review of Biochemistry	1997
9224805	Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997).	Molecular Pharmacology	1997
8626805	Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activity.	Journal of Biological Chemistry	1996
8707816	Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.	Journal of Cell Biology	1996
7761430	Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.	Proceedings of the National Academy of Sciences of the United States of America	1995
7797474	Resolved phospholipase D activity is modulated by cytosolic factors other than Arf.	Journal of Biological Chemistry	1995
7797473	Partial purification and characterization of Arf-sensitive phospholipase D from porcine brain.	Journal of Biological Chemistry	1995
8583935	Stimulation of phospholipase D by ADP-ribosylation factor.	Methods in Enzymology	1995
7934994	Synthesis and applications of affinity matrix containing immobilized beta gamma subunits of G proteins.	Methods in Enzymology	1994