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Author Details

Francesca Fallarino
University of Perugia
1995
180
65
PMIDPaper TitleJournal TitlePublished Year
36346356CAR T cell-driven cerebrospinal fluid cytokine storm with confounding neurological picture in chemorefractory primary cardiac lymphoma.Am J Hematol2023
37603180In Vitro Study of TLR4-NLRP3-Inflammasome Activation in Innate Immune Response.Methods Mol Biol2023
37387273A back-door insight into the modulation of Src kinase activity by the polyamine spermidine.Elife2023
37081894A tryptophan metabolite prevents depletion of circulating endothelial progenitor cells in systemic low-grade inflammation.Front Immunol2023
36831194Extracellular Vesicles in Aging: An Emerging Hallmark?Cells2023
36768851Microbiota-Associated HAF-EVs Regulate Monocytes by Triggering or Inhibiting Inflammasome Activation.Int J Mol Sci2023
36733497The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma.Oncoimmunology2023
36896128The circadian control of tryptophan metabolism regulates the host response to pulmonary fungal infections.PNAS Nexus2023
36484163Immune correlates of protection by vaccine against SARS-CoV-2 in patients with chronic lymphocytic leukaemia.Br J Haematol2023
34847078Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.J Clin Invest2022
35704993Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.Immunity2022
35491676Liver gene therapy with intein-mediated F8 trans-splicing corrects mouse haemophilia A.EMBO Mol Med2022
33749789Systemic administration of sunflower oil exerts neuroprotection in a mouse model of transient focal cerebral ischaemia.J Pharm Pharmacol2022
35218567Amniotic fluid stem cell-derived extracellular vesicles are independent metabolic units capable of modulating inflammasome activation in THP-1 cells.FASEB J2022
33451129The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions.Int J Mol Sci2021
33646117Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism.Elife2021
33924971Tryptophan Metabolites at the Crossroad of Immune-Cell Interaction via the Aryl Hydrocarbon Receptor: Implications for Tumor Immunotherapy.Int J Mol Sci2021
33503414Aspergillus fumigatus tryptophan metabolic route differently affects host immunity.Cell Rep2021
33693650Novel mutations in the WFS1 gene are associated with Wolfram syndrome and systemic inflammation.Hum Mol Genet2021
34388589Prevalence of vitamin D deficiency and its prognostic impact on patients hospitalized with COVID-19.Nutrition2021
342902433-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.Nat Commun2021
32160459Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor.J Med Chem2020
31727470Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs).Eur J Med Chem2020
32024760Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.Proc Natl Acad Sci U S A2020
31867855HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53-dependent mitochondrial apoptosis.EMBO Rep2020
33060567HOPS/Tmub1 involvement in the NF-kB-mediated inflammatory response through the modulation of TRAF6.Cell Death Dis2020
33159421Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.EMBO Rep2020
32765517Editorial: Immunomodulatory Roles of Tryptophan Metabolites in Inflammation and Cancer.Front Immunol2020
32705604Is Acetylsalicylic Acid a Safe and Potentially Useful Choice for Adult Patients with COVID-19 ?Drugs2020
32616652Garcinoic acid prevents β-amyloid (Aβ) deposition in the mouse brain.J Biol Chem2020
32330284The cellular prion protein beyond prion diseases.Swiss Med Wkly2020
32351505Tolerance to FVIII: Role of the Immune Metabolic Enzymes Indoleamine 2,3 Dyoxigenase-1 and Heme Oxygenase-1.Front Immunol2020
32226425Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine.Front Immunol2020
30521884Targeting indoleamine-2,3-dioxygenase in cancer: Scientific rationale and clinical evidence.Pharmacol Ther2019
31265195Toll-like receptors as novel therapeutic targets for herpes simplex virus infection.Rev Med Virol2019
31481962Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.Front Immunol2019
31445234Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation.Eur J Med Chem2019
30793469IL-35Ig-expressing dendritic cells induce tolerance via Arginase 1.J Cell Mol Med2019
30760888Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond.Nat Rev Drug Discov2019
29266750Binding Mode and Structure-Activity Relationships of ITE as an Aryl Hydrocarbon Receptor (AhR) Agonist.ChemMedChem2018
29886240S1P promotes migration, differentiation and immune regulatory activity in amniotic-fluid-derived stem cells.Eur J Pharmacol2018
29934535Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.Nat Med2018
29934534Author Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.Nat Med2018
30291246Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration.Nat Commun2018
29471184Targeting metabotropic glutamate receptors for the treatment of neuroinflammation.Curr Opin Pharmacol2018
29574719IL-35, a hallmark of immune-regulation in cancer progression, chronic infections and inflammatory diseases.Int J Cancer2018
29486616Opportunities and challenges in drug discovery targeting metabotropic glutamate receptor 4.Expert Opin Drug Discov2018
29563329Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes.JCI Insight2018
29277308Nrf2 as regulator of innate immunity: A molecular Swiss army knife!Biotechnol Adv2018
29022506Autologous Cell Therapy for Vascular Regeneration: The Role of Proangiogenic Cells.Curr Med Chem2018
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Collaborators

Ursula Grohmann
University of Perugia
Co-authored papers 65
Marco Gargaro
University of Perugia
Co-authored papers 44
Giada Mondanelli
University of Perugia
Co-authored papers 19
Giorgia Manni
University of Perugia
Co-authored papers 18
Antonio Macchiarulo
Department of Pharmaceutical Sciences, University of Perugia
Co-authored papers 15
Laura Santambrogio
Weill Cornell School of Medicine
Co-authored papers 4
Marc Veldhoen
Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa
Co-authored papers 2
Douglas R Cavener
Co-authored papers 2
David M Kranz
Co-authored papers 2
Carlota Lopez Cara
Department of Pharmaceutical and Organic Chemistry, University of Granada
Co-authored papers 2
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
Roberta Galarini
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati"
Co-authored papers 2
Cristina C Clement
Englander Institute for Precision Medicine
Co-authored papers 1
Sheila Spada
Weill Cornell Medical College
Co-authored papers 1
Matthew R Redinbo
University of North Carolina at Chapel Hill
Co-authored papers 1
Simone Moretti
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati"
Co-authored papers 1
Kari Alitalo
Wihuri Research Institute
Co-authored papers 1
Sarah Gehrke
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Wanxia Li Tsai
National Institute of Arthritis
Co-authored papers 1
Gr??goire Lauvau
Albert Einstein College of Medicine
Co-authored papers 1
Rajesh K Soni
Herbert Irving Comprehensive Cancer Center, Columbia University
Co-authored papers 1
Rub??n Fern??ndez-Rodr??guez
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Cornelia Halin
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 1
Sandra Demaria
Weill Cornell Medical College
Co-authored papers 1
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
Co-authored papers 1
Peter Runge
Institute of Pharmaceutical Sciences, ETH Zurich
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Ettore Appella
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Silvia C Formenti
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Release 1.2