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Author Details

Simon Tavar??
Irving Institute for Cancer Dynamics, Columbia University
1979
173
64
PMIDPaper TitleJournal TitlePublished Year
36929873Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia.Cancer Discov2023
37956120Correction: Spatial regulation of Drosophila ovarian Follicle Stem Cell division rates and cell cycle transitions.PLoS Genet2023
33303580CamGFR v2: A New Model for Estimating the Glomerular Filtration Rate from Standardized or Non-standardized Creatinine in Patients with Cancer.Clin Cancer Res2021
32576827The mutREAD method detects mutational signatures from low quantities of cancer DNA.Nat Commun2020
31235509Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses.J Exp Med2019
31750418Multicenter Validation of the CamGFR Model for Estimated Glomerular Filtration Rate.JNCI Cancer Spectr2019
29704515Ancestral inference from haplotypes and mutations.Theor Popul Biol2018
30025565Introduction to the Paul Joyce special issue.Theor Popul Biol2018
29555768Division-independent differentiation mandates proliferative competition among stem cells.Proc Natl Acad Sci U S A2018
29779891Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.Cell Stem Cell2018
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
29432792Simulating the component counts of combinatorial structures.Theor Popul Biol2018
28686534New Model for Estimating Glomerular Filtration Rate in Patients With Cancer.J Clin Oncol2017
28138154Corrigendum: Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.Nat Genet2017
28465312A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy.Genome Res2017
28974564Corrigendum: A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy.Genome Res2017
28851861Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.Nat Commun2017
27154433Erratum to: Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes.Genome Biol2016
27595477Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.Nat Genet2016
27266441HDTD: analyzing multi-tissue gene expression data.Bioinformatics2016
25560400HES5 silencing is an early and recurrent change in prostate tumourigenesis.Endocr Relat Cancer2015
26491426Metabolomic changes during cellular transformation monitored by metabolite-metabolite correlation analysis and correlated with gene expression.Metabolomics2015
26657335Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target.J Natl Cancer Inst2015
26159513Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis.BMC Genomics2015
25615804Testing the mean matrix in high-dimensional transposable data.Biometrics2015
25717151Genetic mapping of natural variation in schooling tendency in the threespine stickleback.G3 (Bethesda)2015
25790137Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.PLoS Genet2015
25722372multiSNV: a probabilistic approach for improving detection of somatic point mutations from multiple related tumour samples.Nucleic Acids Res2015
25406193Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone.Cancer Res2015
25573856Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia.Arterioscler Thromb Vasc Biol2015
24281695Flexible analysis of RNA-seq data using mixed effects models.Bioinformatics2014
25432628Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists.BMC Cancer2014
25452765Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data.Front Genet2014
24952744Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.Nat Genet2014
24504085Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics.PLoS One2014
24711654Normalization of metabolomics data with applications to correlation maps.Bioinformatics2014
23090114Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization.Cancer Res2013
24035355Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.Cell Stem Cell2013
24264992Defining stem cell dynamics in models of intestinal tumor initiation.Science2013
23629964The level of origin firing inversely affects the rate of replication fork progression.J Cell Biol2013
23762276The relative timing of mutations in a breast cancer genome.PLoS One2013
23412337Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.Proc Natl Acad Sci U S A2013
23300480Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes.PLoS Genet2013
23296680Assessing senescence in Drosophila using video tracking.Methods Mol Biol2013
23034355Three-dimensional tracking and behaviour monitoring of multiple fruit flies.J R Soc Interface2013
22265405Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae.Cell2012
22795131Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.Mol Cell2012
22829875Using GFP video to track 3D movement and conditional gene expression in free-moving flies.PLoS One2012
22912679Calling sample mix-ups in cancer population studies.PLoS One2012
22522925The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.Nature2012
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Collaborators

Andy G Lynch
University of St Andrews
Co-authored papers 28
Mark J Dunning
The Medical School, The University of Sheffield
Co-authored papers 15
Christina Curtis
Stanford University School of Medicine
Co-authored papers 13
John C Marioni
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 12
Carlos Caldas
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 9
Matthew E Ritchie
The University of Melbourne
Co-authored papers 8
Emmanouil T Dermitzakis
University of Geneva
Co-authored papers 7
James D Brenton
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 7
Matthew D Eldridge
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 7
Panos Deloukas
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 6
Andrea Sottoriva
The Institute of Cancer Research, UK Computational Biology Research Centre
Co-authored papers 6
Masashi Narita
Co-authored papers 6
Barbara E Stranger
Center for Genetic Medicine, Northwestern University Feinberg School of Medicine
Co-authored papers 5
Lawrence Bower
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 4
Anne Y Warren
Cambridge University Hospitals National Health Service Foundation Trust
Co-authored papers 4
Peter Donnelly
University of Oxford
Co-authored papers 4
Charlie E Massie
University of Cambridge
Co-authored papers 4
David E Neal
University of Oxford, John Radcliffe Hospital
Co-authored papers 4
Basetti Madhu
Co-authored papers 3
Nigel P Carter
4Wellcome Trust Sanger Institute
Co-authored papers 3
Duncan T Odom
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 3
Samuel Aparicio
University of British Columbia
Co-authored papers 3
Paul Flicek
European Bioinformatics Institute
Co-authored papers 3
Nicholas Brian Shannon
Singapore General Hospital
Co-authored papers 3
Michael D Wilson
SickKids Research Institute
Co-authored papers 3
Louis Vermeulen
Oncode Institute
Co-authored papers 3
Stefan Gr??f
Heart and Lung Research Institute, University of Cambridge
Co-authored papers 3
Antigone S Dimas
Co-authored papers 3
Vincent Peter Collins
Mount Sinai Hospital
Co-authored papers 3
Andrew E Teschendorff
UCL Cancer Institute, University College London
Co-authored papers 3
Release 1.2