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Author Details

Leonard C Schalkwyk
University of Essex
1986
164
58
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37597113Insights into ageing rates comparison across tissues from recalibrating cerebellum DNA methylation clock.Geroscience2024
36726473Genome-wide characterization of mitochondrial DNA methylation in human brain.Front Endocrinol (Lausanne)2023
36539387Uncertainty quantification of reference-based cellular deconvolution algorithms.Epigenetics2023
36566336Social mobility across the lifecourse and DNA methylation age acceleration in adults in the UK.Sci Rep2022
35771651InterpolatedXY: a two-step strategy to normalize DNA methylation microarray data avoiding sex bias.Bioinformatics2022
35568878Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array.Clin Epigenetics2022
35567415Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays.Hum Mol Genet2022
34112773A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.Nat Commun2021
34788620Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.Cell Rep2021
34493871Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.Nat Genet2021
34182928DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy.BMC Genomics2021
33300551Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.Brain2020
33048947The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations.PLoS Genet2020
30380002THE AUTHORS REPLY.Am J Epidemiol2019
31847916Systematic underestimation of the epigenetic clock and age acceleration in older subjects.Genome Biol2019
31719968RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation.Mol Autism2019
31767039DNA methylation aging clocks: challenges and recommendations.Genome Biol2019
31220268Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue.Hum Mol Genet2019
31088362Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array.BMC Genomics2019
30875430Bigmelon: tools for analysing large DNA methylation datasets.Bioinformatics2019
30691483Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains.Mol Brain2019
28630453Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder.Mol Psychiatry2018
30060108Socioeconomic Position and DNA Methylation Age Acceleration Across the Life Course.Am J Epidemiol2018
30401456Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits.Am J Hum Genet2018
30349106A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex.Nat Neurosci2018
30419947Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders.Genome Biol2018
29550519Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.Alzheimers Dement2018
27696737Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression.Am J Med Genet B Neuropsychiatr Genet2017
28140401Advanced paternal age effects in neurodevelopmental disorders-review of potential underlying mechanisms.Transl Psychiatry2017
28433087Paternal Age Alters Social Development in Offspring.J Am Acad Child Adolesc Psychiatry2017
28473874Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue.Clin Epigenetics2017
28208064Mitochondrial genes are altered in blood early in Alzheimer's disease.Neurobiol Aging2017
28145470Genetic polymorphisms and their association with brain and behavioural measures in heterogeneous stock mice.Sci Rep2017
289230165-hydroxymethylcytosine is highly dynamic across human fetal brain development.BMC Genomics2017
28011714Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions.Hum Mol Genet2017
26997371Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans.Nat Commun2016
26619357Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci.Nat Neurosci2016
26452388ViPAR: a software platform for the Virtual Pooling and Analysis of Research Data.Int J Epidemiol2016
27522519Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain.Neurobiol Aging2016
27572077An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation.Genome Biol2016
27317424Erratum to: Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.Genome Biol2016
26888158Comparative mRNA analysis of behavioral and genetic mouse models of aggression.Am J Med Genet B Neuropsychiatr Genet2016
27090961Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish.Am J Med Genet B Neuropsychiatr Genet2016
26883014Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.Genome Biol2016
26786711Tissue-specific patterns of allelically-skewed DNA methylation.Epigenetics2016
24524646The inflammatory cytokines: molecular biomarkers for major depressive disorder?Biomark Med2015
26457534Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes.Epigenetics2015
26096767Effects of advanced paternal age on trajectories of social behavior in offspring.Genes Brain Behav2015
25879669Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains.BMC Genomics2015
25650246Methylomic trajectories across human fetal brain development.Genome Res2015
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Collaborators

Jonathan Mill
University of Exeter Medical School, University of Exeter.
Co-authored papers 59
Eilis Hannon
University of Exeter Medical School, University of Exeter.
Co-authored papers 32
Robert Plomin
Co-authored papers 19
Joe Burrage
University of Exeter Medical School, University of Exeter
Co-authored papers 14
Emma L Dempster
University of Exeter Medical School, University of Exeter
Co-authored papers 13
Peter McGuffin
Co-authored papers 12
Meena Kumari
Co-authored papers 12
Safa Al-Sarraj
Co-authored papers 8
Chloe C Y Wong
Co-authored papers 8
Nicholas J Bray
Division of Psychological Medicine & Clinical Neurosciences, Cardiff University
Co-authored papers 7
Abraham Reichenberg
Co-authored papers 7
Anne Farmer
Co-authored papers 6
David A Collier
Institute of Psychiatry, King's College London
Co-authored papers 6
Aaron R Jeffries
University of Exeter
Co-authored papers 6
Simon Lovestone
Janssen Medical Ltd
Co-authored papers 5
David A Bennett
Rush University Medical Center
Co-authored papers 4
Gerome Breen
Institute of Psychiatry, King's College London
Co-authored papers 4
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British Columbia Cancer Research Institute
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Philip L De Jager
Columbia University Medical Center
Co-authored papers 4
Robert W Williams
Mayo Clinic
Co-authored papers 4
Pak C Sham
the University of Hong Kong
Co-authored papers 3
Stephan Beck
UCL Cancer Institute, University College London
Co-authored papers 3
Gustavo Turecki
Douglas Institute, McGill University
Co-authored papers 3
Lu Lu
University of Tennessee Health Science Center
Co-authored papers 3
Elissa J Chesler
Center for Systems Neurogenetics of Addiction at The Jackson Laboratory
Co-authored papers 3
Jordana T Bell
King's College London
Co-authored papers 3
Michael N Weedon
Co-authored papers 3
Vahram Haroutunian
Co-authored papers 3
Thomas S Price
at the University of Pennsylvania Perelman School of Medicine
Co-authored papers 3
Joseph D Buxbaum
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Release 1.2