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Author Details
Full Name
Dennis J Hoover
Affiliation
Synaptic Dynamics Inc.
ORCID
Career Start Year
1981
Papers
43
H Index
26
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
22944582
Uranium quantification in semen by inductively coupled plasma mass spectrometry.
J Trace Elem Med Biol
2013
24215237
Discovery and characterization of a novel dihydroisoxazole class of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiators.
J Med Chem
2013
23439138
The Gulf War depleted uranium cohort at 20 years: bioassay results and novel approaches to fragment surveillance.
Health Phys
2013
24900408
Nonpeptidic lysosomal modulators derived from z-phe-ala-diazomethylketone for treating protein accumulation diseases.
ACS Med Chem Lett
2012
21432717
Longitudinal health surveillance in a cohort of Gulf War veterans 18 years after first exposure to depleted uranium.
J Toxicol Environ Health A
2011
18979351
Surveillance results of depleted uranium-exposed Gulf War I veterans: sixteen years of follow-up.
J Toxicol Environ Health A
2009
17194716
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Drug Metab Dispos
2007
17563493
Health surveillance of Gulf War I veterans exposed to depleted uranium: updating the cohort.
Health Phys
2007
16075297
Biological monitoring and surveillance results of Gulf War I veterans exposed to depleted uranium.
Int Arch Occup Environ Health
2006
16537796
Establishment of correlation between in vitro enzyme binding potency and in vivo pharmacological activity: application to liver glycogen phosphorylase a inhibitors.
J Pharmacol Exp Ther
2006
15450757
Prenatal HgCl2 exposure in BALB/c mice: gender-specific effects on the ontogeny of the immune system.
Dev Comp Immunol
2005
15604516
Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.
J Lipid Res
2005
14713562
Health effects of depleted uranium on exposed Gulf War veterans: a 10-year follow-up.
J Toxicol Environ Health A
2004
12896845
Low-dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupus.
Environ Health Perspect
2003
12204691
Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.
Chem Biol
2002
11765683
Surveillance of depleted uranium exposed Gulf War veterans: health effects observed in an enlarged "friendly fire" cohort.
J Occup Environ Med
2001
11227044
Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus.
Expert Opin Investig Drugs
2001
10662531
Health effects of depleted uranium on exposed Gulf War veterans.
Environ Res
2000
10898591
Lead interaction with human protamine (HP2) as a mechanism of male reproductive toxicity.
Chem Res Toxicol
2000
10940971
Lead effects on protamine-DNA binding.
Am J Ind Med
2000
10980448
Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.
Chem Biol
2000
11061973
X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J Mol Biol
2000
9862200
A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.
Protein Eng
1998
9465093
Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo.
Proc Natl Acad Sci U S A
1998
9685232
Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.
J Med Chem
1998
9135120
The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae.
J Mol Biol
1997
8540316
Discovery of inhibitors of human renin with high oral bioavailability.
Adv Exp Med Biol
1995
1304340
Direct observation by X-ray analysis of the tetrahedral "intermediate" of aspartic proteinases.
Protein Sci
1992
1525154
Synthesis and crystallographic analysis of two rhizopuspepsin inhibitor complexes.
Biochemistry
1992
1472368
Rat Sertoli and spermatogenic cells express a similar gene, and its product is antigenically related to an outer dense fiber-associated protein.
Mol Reprod Dev
1992
1472369
Developmental expression of the S35-S45/SGP-2/TRPM-2 gene in rat testis and epididymis.
Mol Reprod Dev
1992
1954879
Androgen metabolism by porcine granulosa cells during the process of luteinization in vitro: identification of 19-oic-androstenedione as a major metabolite and possible precursor for the formation of C18 neutral steroids.
Endocrinology
1991
1812709
Crystal structures of rhizopuspepsin/inhibitor complexes.
Adv Exp Med Biol
1991
1812716
X-ray analysis of a difluorostatone renin inhibitor bound as the tetrahedral hydrate to the aspartic protease endothiapepsin.
Adv Exp Med Biol
1991
2676515
High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.
EMBO J
1989
6300233
Immunologic and ionophore-induced generation of leukotriene B4 from mouse bone marrow-derived mast cells.
J Immunol
1983
6411912
Changes in inhibin activity, and progesterone, oestrogen and androstenedione concentrations, in rat follicular fluid throughout the oestrous cycle.
J Reprod Fertil
1983
6221518
Biology of the C-6-sulfidopeptide leukotrienes.
Adv Prostaglandin Thromboxane Leukot Res
1983
6289394
The role of nonsteroidal regulators in control of oocyte and follicular maturation.
Recent Prog Horm Res
1982
6817606
Hormonal control of inhibin secretion.
Adv Exp Med Biol
1982
6296855
Radioimmunoassay for leukotriene B4.
Proc Natl Acad Sci U S A
1982
6796149
Inhibitory effects of porcine follicular fluid on monkey serum FSH levels and follicular maturation.
Biol Reprod
1981
7014598
Relationship between human follicular fluid inhibin F activity and steroid content.
J Clin Endocrinol Metab
1981
1 - 43 of 43
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Heartand Lung Research Institute, University of Cambridge
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University College London
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Pfizer Inc.
Co-authored papers
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K F Austen
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Co-authored papers
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David B Damon
Co-authored papers
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B W Dominy
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Christine Humblet
Lilly Research Laboratories
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Christopher J O'Donnell
Brigham and Women's Hospital, Harvard Medical School
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Hoag Memorial Hospital Presbyterian
Co-authored papers
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Robert J Fletterick
University of California San Francisco
Co-authored papers
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Mark S Johnson
Abo Akademi University
Co-authored papers
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1 - 13