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Author Details

Derek Barclay
University of Pittsburgh
2006
47
20
PMIDPaper TitleJournal TitlePublished Year
37251389Peripheral nerve repair is associated with augmented cross-tissue inflammation following vascularized composite allotransplantation.Front Immunol2023
38034362A common single nucleotide polymorphism is associated with inflammation and critical illness outcomes.iScience2023
35663944Inferring Tissue-Specific, TLR4-Dependent Type 17 Immune Interactions in Experimental Trauma/Hemorrhagic Shock and Resuscitation Using Computational Modeling.Front Immunol2022
33958628A putative "chemokine switch" that regulates systemic acute inflammation in humans.Sci Rep2021
33519820Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver Failure.Front Immunol2021
33537029Computational Derivation of Core, Dynamic Human Blunt Trauma Inflammatory Endotypes.Front Immunol2021
34988152Inflammatory signals and network connections implicate cell-mediated immunity in chronic venous insufficiency.Ann Transl Med2021
34017323The Effects of Tacrolimus on Tissue-Specific, Protein-Level Inflammatory Networks in Vascularized Composite Allotransplantation.Front Immunol2021
33935273Baseline Plasma Inflammatory Profile Is Associated With Response to Neoadjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma.J Immunother2021
31318836An Aging-Related Single-Nucleotide Polymorphism is Associated With Altered Clinical Outcomes and Distinct Inflammatory Profiles in Aged Blunt Trauma Patients.Shock2020
32229722Prehospital plasma is associated with distinct biomarker expression following injury.JCI Insight2020
30979951HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen.Sci Rep2019
31781170<i>MPPED2</i> Polymorphism Is Associated With Altered Systemic Inflammation and Adverse Trauma Outcomes.Front Genet2019
31824494Diurnal Variation in Systemic Acute Inflammation and Clinical Outcomes Following Severe Blunt Trauma.Front Immunol2019
31555685Decoding the secreted inflammatory response of primary human hepatocytes to hypoxic stress <i>in vitro</i>.Ann Transl Med2019
28930911An Enrichment Strategy Yields Seven Novel Single Nucleotide Polymorphisms Associated With Mortality and Altered Th17 Responses Following Blunt Trauma.Shock2018
30399158A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice.PLoS Comput Biol2018
29439934Suppressed networks of inflammatory mediators characterize chronic venous insufficiency.J Vasc Surg Venous Lymphat Disord2018
27900388Data-Driven Modeling for Precision Medicine in Pediatric Acute Liver Failure.Mol Med2017
29312006"Thinking" vs. "Talking": Differential Autocrine Inflammatory Networks in Isolated Primary Hepatic Stellate Cells and Hepatocytes under Hypoxic Stress.Front Physiol2017
25371118Temporal Patterns of Circulating Inflammation Biomarker Networks Differentiate Susceptibility to Nosocomial Infection Following Blunt Trauma in Humans.Ann Surg2016
27867357Machine Perfusion of Porcine Livers with Oxygen-Carrying Solution Results in Reprogramming of Dynamic Inflammation Networks.Front Pharmacol2016
27513538Computational Analysis Supports an Early, Type 17 Cell-Associated Divergence of Blunt Trauma Survival and Mortality.Crit Care Med2016
25342131Injury-induced MRP8/MRP14 stimulates IP-10/CXCL10 in monocytes/macrophages.FASEB J2015
26635801Cardiac Arrest Disrupts Caspase-1 and Patterns of Inflammatory Mediators Differently in Skin and Muscle Following Localized Tissue Injury in Rats: Insights from Data-Driven Modeling.Front Immunol2015
26064799Impact of chemically-modified tetracycline 3 on intertwined physiological, biochemical, and inflammatory networks in porcine sepsis/ARDS.Int J Burns Trauma2015
25925680Trauma in silico: Individual-specific mathematical models and virtual clinical populations.Sci Transl Med2015
26004155In vivo and systems biology studies implicate IL-18 as a central mediator in chronic pain.J Neuroimmunol2015
25612645Liver preservation with machine perfusion and a newly developed cell-free oxygen carrier solution under subnormothermic conditions.Am J Transplant2015
24140737Identification of distinct monocyte phenotypes and correlation with circulating cytokine profiles in acute response to spinal cord injury: a pilot study.PM R2014
24926998Insights from computational modeling in inflammation and acute rejection in limb transplantation.PLoS One2014
23073658Augmenter of liver regeneration (ALR) is a novel biomarker of hepatocellular stress/inflammation: in vitro, in vivo and in silico studies.Mol Med2013
24312451Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies.PLoS One2013
24244295Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure.PLoS One2013
23844008Combined in silico, in vivo, and in vitro studies shed insights into the acute inflammatory response in middle-aged mice.PLoS One2013
22425816A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine.Crit Care Med2012
22751621Hemoadsorption reprograms inflammation in experimental gram-negative septic peritonitis: insights from in vivo and in silico studies.Mol Med2012
22293598Persistence of elevated plasma CXCL8 concentrations following red blood cell transfusion in a trauma cohort.Shock2012
19784793Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study.Int Urol Nephrol2010
19008782Mathematical modeling of posthemorrhage inflammation in mice: studies using a novel, computer-controlled, closed-loop hemorrhage apparatus.Shock2009
20027315An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage.PLoS One2009
19691848Gender-based reciprocal expression of transforming growth factor-beta1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis.J Inflamm (Lond)2009
19614923Activation of latent transforming growth factor-beta1 by nitric oxide in macrophages: role of soluble guanylate cyclase and MAP kinases.Wound Repair Regen2009
18848347Multiplex analysis of urinary cytokine levels in rat model of cyclophosphamide-induced cystitis.Urology2009
18623112A simple, rapid, and convenient Luminex-compatible method of tissue isolation.J Clin Lab Anal2008
18924007Helicopter scene response: regional variation in compliance with air medical triage guidelines.Prehosp Emerg Care2008
17065633Videos in clinical medicine. Basic laceration repair.N Engl J Med2006
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Collaborators

University of Pittsburgh
Co-authored papers 45
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University of Pittsburgh
Co-authored papers 21
University of Pittsburgh
Co-authored papers 11
Medical Subspecialities Institute, Cleveland Clinic
Co-authored papers 7
University of Pittsburgh
Co-authored papers 4
University of Pittsburgh Medical Center
Co-authored papers 4
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
Co-authored papers 4
University of Pittsburgh Medical Center
Co-authored papers 3
University of Pittsburgh
Co-authored papers 3
Pontificia Universidad Javeriana
Co-authored papers 3
Hunterdon Medical Center
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University of Pittsburgh
Co-authored papers 2
Co-authored papers 2
University Medical Center Groningen
Co-authored papers 2
and Clinical Translational Science, University of Pittsburgh
Co-authored papers 2
The Pennsylvania State University, University Park
Co-authored papers 2
University of Pittsburgh
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Gangnam Severance Hospital, Yonsei University College of Medicine
Co-authored papers 1
Zhongnan Hospital of Wuhan University
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Center for Critical Care Nephrology, University of Pittsburgh
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Ann & Robert H. Lurie Children's Hospital of Chicago
Co-authored papers 1
University of Pittsburgh Medical Center
Co-authored papers 1
University of Texas Southwestern Medical Center
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Center for Critical Care Nephrology, University of Pittsburgh School of Medicine
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University of Pittsburgh Medical Center
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