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Author Details

David Altshuler
Broad Institute of Harvard and Massachusetts Institute of Technology (MIT)
1992
279
138
PMIDPaper TitleJournal TitlePublished Year
36920755Inaxaplin for Proteinuric Kidney Disease in Persons with Two <i>APOL1</i> Variants.N Engl J Med2023
36920755Inaxaplin for Proteinuric Kidney Disease in Persons with Two <i>APOL1</i> Variants.N Engl J Med2023
33402679Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nat Commun2021
33558525Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nat Commun2021
33283989CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.N Engl J Med2021
33402679Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nat Commun2021
33558525Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nat Commun2021
33283989CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.N Engl J Med2021
31948569Functional characterization of tumor antigen-specific T-cells isolated from the tumor microenvironment of sleeping beauty induced murine glioma models.Methods Enzymol2020
31948569Functional characterization of tumor antigen-specific T-cells isolated from the tumor microenvironment of sleeping beauty induced murine glioma models.Methods Enzymol2020
32000905Isolation and characterization of immune cells from the tumor microenvironment of genetically engineered pediatric high-grade glioma models using the sleeping beauty transposon system.Methods Enzymol2020
32000905Isolation and characterization of immune cells from the tumor microenvironment of genetically engineered pediatric high-grade glioma models using the sleeping beauty transposon system.Methods Enzymol2020
30718883Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes.Eur J Hum Genet2019
31118516Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.Nature2019
30721028High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme.ACS Nano2019
30718883Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes.Eur J Hum Genet2019
31118516Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.Nature2019
30721028High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme.ACS Nano2019
29048572Ventriculoscopic Surgery for Cystic Retrochiasmatic Craniopharyngiomas: Indications, Surgical Technique, and Short-Term Patient Outcomes.Oper Neurosurg (Hagerstown)2018
29048572Ventriculoscopic Surgery for Cystic Retrochiasmatic Craniopharyngiomas: Indications, Surgical Technique, and Short-Term Patient Outcomes.Oper Neurosurg (Hagerstown)2018
29889582Mutant ATRX: uncovering a new therapeutic target for glioma.Expert Opin Ther Targets2018
29899519Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.Nat Commun2018
29660022Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab.Neuro Oncol2018
29421984Current state and future prospects of immunotherapy for glioma.Immunotherapy2018
29279374Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.Proc Natl Acad Sci U S A2018
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
29889582Mutant ATRX: uncovering a new therapeutic target for glioma.Expert Opin Ther Targets2018
29899519Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.Nat Commun2018
29421984Current state and future prospects of immunotherapy for glioma.Immunotherapy2018
29360107Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2018
29660022Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab.Neuro Oncol2018
29279374Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.Proc Natl Acad Sci U S A2018
27899486Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population.Diabetes2017
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
28453780Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.J Clin Endocrinol Metab2017
28838971A Loss-of-Function Splice Acceptor Variant in <i>IGF2</i> Is Protective for Type 2 Diabetes.Diabetes2017
28666119Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.Cell2017
28566273An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Diabetes2017
29257133Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2017
27899486Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population.Diabetes2017
28453780Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention.J Clin Endocrinol Metab2017
28341696A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.Diabetes2017
29257133Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.Sci Data2017
28566273An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Diabetes2017
28666119Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.Cell2017
28838971A Loss-of-Function Splice Acceptor Variant in <i>IGF2</i> Is Protective for Type 2 Diabetes.Diabetes2017
24982446Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.J Clin Oncol2016
26757982Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project.Eur J Hum Genet2016
27422940Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study.Circ Cardiovasc Genet2016
26911676Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.Hum Mol Genet2016
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Collaborators

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Co-authored papers 58
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Baylor College of Medicine
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William Harvey Research Institute, Queen Mary University of London
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Broad Institute of MIT and Harvard
Co-authored papers 28
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University of Southern California
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Vertex Pharmaceuticals
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