Author details

Full Name

Douglas C Wallace

Affiliation

ORCID

Career Start Year

1970

Papers

426

H Index

122

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36635485	OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.	Commun Biol	2023
37598215	APOGEE 2: multi-layer machine-learning model for the interpretable prediction of mitochondrial missense variants.	Nat Commun	2023
37580812	Optimization of differential filtration-based mitochondrial isolation for mitochondrial transplant to cerebral organoids.		2023
38076862	SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.	medRxiv	2023
37556555	Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts.	Sci Transl Med	2023
37289571	Super-Resolution Imaging of Voltages in the Interior of Individual, Vital Mitochondria.		2023
36899051	Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling.		2023
36891303	SARS-COV-2 viroporins activate the NLRP3-inflammasome by the mitochondrial permeability transition pore.	Front Immunol	2023
34966070	Influence of Immune Cell Subtypes on Mitochondrial Measurements in Peripheral Blood Mononuclear Cells From Children with Sepsis.	Shock	2022
35714845	The mitochondrial adenine nucleotide transporters in myogenesis.	Free Radical Biology and Medicine	2022
35759301	Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation.	Shock	2022
35502898	A Three-Dimensional Printed Inertial Microfluidic Platform for Isolation of Minute Quantities of Vital Mitochondria.	Analytical Chemistry	2022
36216300	Preface.	Free Radical Biology and Medicine	2022
35482926	Mitochondrial mutations alter endurance exercise response and determinants in mice.	Proc Natl Acad Sci U S A	2022
36125045	Promoting validation and cross-phylogenetic integration in model organism research.	Dis Model Mech	2022
36322731	Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.	Proc Natl Acad Sci U S A	2022
35664076	The interplay between lncRNAs, RNA-binding proteins and viral genome during SARS-CoV-2 infection reveals strong connections with regulatory events involved in RNA metabolism and immune response.	Theranostics	2022
35233572	TARGETED DOWN REGULATION OF CORE MITOCHONDRIAL GENES DURING SARS-COV-2 INFECTION.	bioRxiv	2022
34969639	Advanced approach for comprehensive mtDNA genome testing in mitochondrial disease.	Mol Genet Metab	2022
34943968	Unlocking the Complexity of Mitochondrial DNA: A Key to Understanding Neurodegenerative Disease Caused by Injury.	Cells	2021
33536343	An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes.	Proceedings of the National Academy of Sciences of the United States of America	2021
34009292	Association of Mitochondrial Biogenesis With Variable Penetrance of Schizophrenia.	JAMA Psychiatry	2021
33948587	The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection.	bioRxiv	2021
33786436	Decreased Intestinal Microbiome Diversity in Pediatric Sepsis: A Conceptual Framework for Intestinal Dysbiosis to Influence Immunometabolic Function.	Crit Care Explor	2021
34195227	NADH Fluorescence Lifetime Imaging Microscopy Reveals Selective Mitochondrial Dysfunction in Neurons Overexpressing Alzheimer's Disease-Related Proteins.	Front Mol Biosci	2021
33443141	Genome-wide surveillance of transcription errors in response to genotoxic stress.	Proceedings of the National Academy of Sciences of the United States of America	2021
34624208	Role of miR-2392 in driving SARS-CoV-2 infection.	Cell Rep	2021
33326785	Lactate Limits T Cell Proliferation via the NAD(H) Redox State.	Cell Reports	2020
31949209	HDAC10 deletion promotes Foxp3 T-regulatory cell function.	Scientific Reports	2020
31764621	Mitochondrial Dysfunction is Associated With an Immune Paralysis Phenotype in Pediatric Sepsis.	Shock	2020
33257573	Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.	Proceedings of the National Academy of Sciences of the United States of America	2020
33242417	Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.	Cell	2020
32906214	Specifications of the ACMG/AMP standards and guidelines for mitochondrial DNA variant interpretation.	Hum Mutat	2020
32612279	An ultra-high bandwidth nano-electronic interface to the interior of living cells with integrated fluorescence readout of metabolic activity.	Scientific Reports	2020
30772945	Nutrition and its role in human evolution.	Journal of Internal Medicine	2019
31618756	The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.	Nature	2019
30174309	Mitochondrial DNA Variation Dictates Expressivity and Progression of Nuclear DNA Mutations Causing Cardiomyopathy.		2019
30653964	The association of mitochondrial DNA haplogroups with POAG in African Americans.	Exp Eye Res	2019
30861524	Premature Lambs Exhibit Normal Mitochondrial Respiration after Long-Term Extrauterine Support.	Fetal Diagn Ther	2019
31438578	BK () Channel Regulates Mitochondrial Function and Lifespan in .	Cells	2019
31266851	Host mitochondria influence gut microbiome diversity: A role for ROS.	Sci Signal	2019
31385882	Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis.	Crit Care Med	2019
31253706	Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.	Proc Natl Acad Sci U S A	2019
31341297	H transport is an integral function of the mitochondrial ADP/ATP carrier.	Nature	2019
31007314	Scanning Microwave Microscopy of Vital Mitochondria in Respiration Buffer.	IEEE MTT-S International Microwave Symposium Digest	2018
29044765	A novel inborn error of the coenzyme Q10 biosynthesis pathway: cerebellar ataxia and static encephalomyopathy due to COQ5 C-methyltransferase deficiency.	Hum Mutat	2018
29917077	USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis.	Hum Mol Genet	2018
30242360	Mitochondrial DNA Variation and Disease Susceptibility in Primary Open-Angle Glaucoma.	Invest Ophthalmol Vis Sci	2018
29997041	Mitochondrial DNA associations with East Asian metabolic syndrome.	Biochim Biophys Acta Bioenerg	2018
30526856	Highly efficient 5' capping of mitochondrial RNA with NAD and NADH by yeast and human mitochondrial RNA polymerase.	eLife	2018