Author details

Full Name

Hendrik G Stunnenberg

Affiliation

ORCID

Career Start Year

1978

Papers

360

H Index

102

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37595034	regulates one-carbon metabolism and histone methylation in ground-state pluripotency.		2023
35879361	Uncovering the mode of action of engineered T cells in patient cancer organoids.	Nat Biotechnol	2023
34162697	Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes.	Genome Research	2022
35767439	Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma.	N Engl J Med	2022
35995787	Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease.	Nature Communications	2022
35681235	CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway.	Molecular Cancer	2022
35986270	Longitudinal single-cell transcriptomics reveals distinct patterns of recurrence in acute myeloid leukemia.	Molecular Cancer	2022
36411286	Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability.	Nature Communications	2022
37096022	3D spheroid culture to examine adaptive therapy response in invading tumor cells.		2022
34663697	Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme.	Proceedings of the National Academy of Sciences of the United States of America	2021
34017127	Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes.	Nat Immunol	2021
33630761	Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells.	JCI insight	2021
33953289	Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas.	Leukemia	2021
33567618	The Role of Necroptosis: Biological Relevance and Its Involvement in Cancer.	Cancers	2021
33510161	Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation.	Nat Commun	2021
34321071	Urate-induced epigenetic modifications in myeloid cells.		2021
32703790	Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas.	Haematologica	2021
33293712	Trained immunity, tolerance, priming and differentiation: distinct immunological processes.	Nat Immunol	2021
33016232	Recent insights into : biological function and involvement in pathogenesis.	Epigenetics	2021
34853826	The EHA Research Roadmap: Normal Hematopoiesis.	HemaSphere	2021
33396628	MicroRNA-Assisted Hormone Cell Signaling in Colorectal Cancer Resistance.	Cells	2020
31907411	p120-catenin-dependent collective brain infiltration by glioma cell networks.	Nature Cell Biology	2020
32004494	Critical Role for P53 in Regulating the Cell Cycle of Ground State Embryonic Stem Cells.	Stem Cell Reports	2020
32238817	The translational landscape of ground state pluripotency.	Nature Communications	2020
32111830	Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency.	Nature Communications	2020
32460311	Genes Involved in Energy Metabolism Are Differentially Expressed During the Day-Night Cycle in Murine Retinal Pigment Epithelium.	Investigative Ophthalmology and Visual Science	2020
32912294	STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells.		2020
32667968	Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.	J Exp Med	2020
33324683	Controlled Human Malaria Infection Induces Long-Term Functional Changes in Monocytes.	Frontiers in Molecular Biosciences	2020
30988298	Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.	Nat Commun	2019
31728527	Epigenetic reader complexes of the human malaria parasite, Plasmodium falciparum.	Nucleic Acids Research	2019
31888209	Inhibition of Histone Demethylases LSD1 and UTX Regulates ERÎ± Signaling in Breast Cancer.	Cancers	2019
30206357	Exploring rare and low-frequency variants in the Saguenay-Lac-Saint-Jean population identified genes associated with asthma and allergy traits.	Eur J Hum Genet	2019
30293776	The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.	Cell Metab	2019
31036938	Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.	Nat Cell Biol	2019
30809020	Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages.	Sci Rep	2019
31064398	Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.	Genome Biol	2019
30728416	Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells.	Scientific Reports	2019
30673601	Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes.	Cell Rep	2019
31204280	Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.		2019
31000698	BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition.	Cell Death and Disease	2019
31097792	Publisher Correction: Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.	Nat Cell Biol	2019
29273642	Transcriptional and functional profiling defines human small intestinal macrophage subsets.	Journal of Experimental Medicine	2018
28416808	Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.	Mol Psychiatry	2018
28871137	C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation.	Leukemia	2018
30026265	Mammalian embryo comparison identifies novel pluripotency genes associated with the naÃ¯ve or primed state.	Biol Open	2018
29921844	Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells.	Nature Communications	2018
29876014	Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.	Oncotarget	2018
29876013	Combined HAT/EZH2 modulation leads to cancer-selective cell death.	Oncotarget	2018
30337563	E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer.	Sci Rep	2018