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Author Details
Full Name
Afam A Okoye
Affiliation
Vaccine & Gene Therapy Institute, and Oregon National Primate Research Center
ORCID
Career Start Year
2003
Papers
24
H Index
14
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37801446
Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication.
PLoS Pathog
2023
35041707
The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription.
PLoS Pathog
2022
36162961
Effects of Early Antiretroviral Therapy on the Composition and Diversity of the Fecal Microbiome of SIV-infected Rhesus Macaques (<i>Macaca mulatta</i>).
Comp Med
2022
35316218
Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy.
J Clin Invest
2022
34485613
Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor TÂ cells in rhesus macaques.
Mol Ther Methods Clin Dev
2021
33536176
Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>.
J Virol
2021
33630764
CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.
J Clin Invest
2021
32988211
Real-Time Killing Assays to Assess the Potency of a New Anti-Simian Immunodeficiency Virus Chimeric Antigen Receptor T Cell.
AIDS Res Hum Retroviruses
2020
30430748
Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.
Aging Cell
2019
31653683
Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency Virus Infection in Rhesus Macaques.
J Immunol
2019
31295427
The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.
Cell Host Microbe
2019
31597757
<i>In Vivo</i> Validation of the Viral Barcoding of Simian Immunodeficiency Virus SIVmac239 and the Development of New Barcoded SIV and Subtype B and C Simian-Human Immunodeficiency Viruses.
J Virol
2019
29135580
Wake me up before you go: a strategy to reduce the latent HIV reservoir.
AIDS
2018
30082858
Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.
Nat Med
2018
28514279
Impact of alemtuzumab on HIV persistence in an HIV-infected individual on antiretroviral therapy with Sezary syndrome.
AIDS
2017
27430715
Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques.
J Immunol
2016
25599132
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers.
Nat Med
2015
26416281
Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques.
J Immunol
2015
23772614
CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure.
Immunol Rev
2013
22451717
Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection.
J Exp Med
2012
20622118
Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses.
J Immunol
2010
19546246
Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.
J Exp Med
2009
17724130
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
J Exp Med
2007
12732629
A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis.
J Biol Chem
2003
1 - 24 of 24
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