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Author Details

Afam A Okoye
Vaccine & Gene Therapy Institute, and Oregon National Primate Research Center
2003
24
14
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37801446Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication.PLoS Pathog2023
35041707The ingenol-based protein kinase C agonist GSK445A is a potent inducer of HIV and SIV RNA transcription.PLoS Pathog2022
36162961Effects of Early Antiretroviral Therapy on the Composition and Diversity of the Fecal Microbiome of SIV-infected Rhesus Macaques (<i>Macaca mulatta</i>).Comp Med2022
35316218Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy.J Clin Invest2022
34485613Immune inactivation of anti-simian immunodeficiency virus chimeric antigen receptor T cells in rhesus macaques.Mol Ther Methods Clin Dev2021
33536176Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity <i>Ex Vivo and In Vivo</i>.J Virol2021
33630764CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.J Clin Invest2021
32988211Real-Time Killing Assays to Assess the Potency of a New Anti-Simian Immunodeficiency Virus Chimeric Antigen Receptor T Cell.AIDS Res Hum Retroviruses2020
30430748Lymph nodes as barriers to T-cell rejuvenation in aging mice and nonhuman primates.Aging Cell2019
31653683Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency Virus Infection in Rhesus Macaques.J Immunol2019
31295427The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections.Cell Host Microbe2019
31597757<i>In Vivo</i> Validation of the Viral Barcoding of Simian Immunodeficiency Virus SIVmac239 and the Development of New Barcoded SIV and Subtype B and C Simian-Human Immunodeficiency Viruses.J Virol2019
29135580Wake me up before you go: a strategy to reduce the latent HIV reservoir.AIDS2018
30082858Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.Nat Med2018
28514279Impact of alemtuzumab on HIV persistence in an HIV-infected individual on antiretroviral therapy with Sezary syndrome.AIDS2017
27430715Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques.J Immunol2016
25599132B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers.Nat Med2015
26416281Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques.J Immunol2015
23772614CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failure.Immunol Rev2013
22451717Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection.J Exp Med2012
20622118Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses.J Immunol2010
19546246Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.J Exp Med2009
17724130Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.J Exp Med2007
12732629A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis.J Biol Chem2003
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Collaborators

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Co-authored papers 18
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Co-authored papers 13
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 1
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Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
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Gladstone Institute of Virology, Gladstone Institutes
Co-authored papers 1
AMO Pharma Ltd.
Co-authored papers 1
University of California, USA Gladstone Institutes san francisco
Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Institute for Translational HIV Research, University Hospital Essen
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National Institute of Allergy and Infectious Diseases, National Institutes of Health
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Co-authored papers 1
University Hospital Essen, Institute for Translational HIV Research
Co-authored papers 1
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