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Author Details

Annette Bakker
Children's Tumor Foundation
2004
40
18
PMIDPaper TitleJournal TitlePublished Year
37245145RAS Signaling Gone Awry in the Skin: The Complex Role of RAS in Cutaneous Neurofibroma Pathogenesis, Emerging Biological Insights.J Invest Dermatol2023
35266292The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery.Am J Med Genet A2022
34237445Lessons learned from drug trials in neurofibromatosis: A systematic review.Eur J Med Genet2021
33903738Identifying challenges in neurofibromatosis: a modified Delphi procedure.Eur J Hum Genet2021
32814709Phenotypic heterogeneity of neurofibromatosis type 1 in a large international registry.JCI Insight2020
31793149Funding community collaboration to develop effective therapies for neurofibromatosis type 1 tumors.EMBO Mol Med2020
30908866From process to progress-2017 International Conference on Neurofibromatosis 1, Neurofibromatosis 2 and Schwannomatosis.Am J Med Genet A2019
31836719Engaging a community to enable disease-centric data sharing with the NF Data Portal.Sci Data2019
296810992016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis.Am J Med Genet A2018
29695767Cutaneous neurofibromas in the genomics era: current understanding and open questions.Br J Cancer2018
26854064Neurofibromatosis as a gateway to better treatment for a variety of malignancies.Prog Neurobiol2017
28436162The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis.Am J Med Genet A2017
28398289A high-throughput molecular data resource for cutaneous neurofibromas.Sci Data2017
28938910Creating a data resource: what will it take to build a medical information commons?Genome Med2017
29117388Neurofibromatosis Type 1-Associated MPNST State of the Science: Outlining a Research Agenda for the Future.J Natl Cancer Inst2017
28644838Characterization and utilization of an international neurofibromatosis web-based, patient-entered registry: An observational study.PLoS One2017
28743783Rethinking the nonprofit foundation: an emerging niche in the rare disease ecosystem.EMBO Mol Med2017
27155140The Fourth International Symposium on Genetic Disorders of the Ras/MAPK pathway.Am J Med Genet A2016
27845557The National Disease Research Interchange and Collaborators on: What Are the Major Hurdles to the Recovery of Human Tissue to Advance Research?Biopreserv Biobank2016
25940629NFFinder: an online bioinformatics tool for searching similar transcriptomics experiments in the context of drug repositioning.Nucleic Acids Res2015
25900621The third international meeting on genetic disorders in the RAS/MAPK pathway: towards a therapeutic approach.Am J Med Genet A2015
25847770Structure-activity relationship and properties optimization of a series of quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway.Eur J Med Chem2015
24443315CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.Am J Med Genet A2014
25255738Update from the 2013 International Neurofibromatosis Conference.Am J Med Genet A2014
23619303Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells.Mol Cancer Ther2013
23825539Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts.PLoS One2013
22072503In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines.Int J Cancer2012
23284888A radial glia gene marker, fatty acid binding protein 7 (FABP7), is involved in proliferation and invasion of glioblastoma cells.PLoS One2012
20426768Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells.Biosci Rep2011
21321483β-catenin and Gli1 are prognostic markers in glioblastoma.Cancer Biol Ther2011
19545421KIF11 inhibition for glioblastoma treatment: reason to hope or a struggle with the brain?BMC Cancer2009
19434656How to achieve confidence in drug discovery and development: managing risk (from a reductionist to a holistic approach).ChemMedChem2009
18444511Delivery of a DNAzyme targeting c-myc to HT29 colon carcinoma cells using a gold nanoparticulate approach.Pharmazie2008
16608734Modified poly(propylene imine) dendrimers as effective transfection agents for catalytic DNA enzymes (DNAzymes).J Drug Target2006
17718951Dendrimeric poly(propylene-imines) as effective delivery agents for DNAzymes: toxicity, in vitro transfection and in vivo delivery.J Control Release2006
17718950Dendrimeric poly(propylene-imines) as effective delivery agents for DNAzymes: dendrimer synthesis, stability and oligonucleotide complexation.J Control Release2006
16307379Two sides of the same coin: Wnt signaling in neurodegeneration and neuro-oncology.Biosci Rep2005
15136766Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles.Cancer Biol Ther2004
15557753Alteration of frizzled expression in renal cell carcinoma.Tumour Biol2004
15527325Housekeeping genes as internal standards in cancer research.Mol Diagn2004
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Collaborators

university of massachusetts amherst Chan Medical School
Co-authored papers 7
Johns Hopkins University
Co-authored papers 6
Children's Tumor Foundation
Co-authored papers 6
Co-authored papers 6
Co-authored papers 5
Co-authored papers 4
Pacific Northwest National Laboratory (PNNL)
Co-authored papers 3
University of Washington
Co-authored papers 3
Frederick National Laboratory for Cancer Research
Co-authored papers 3
Icahn School of Medicine at Mount Sinai
Co-authored papers 3
Boston Children's Hospital, Harvard Medical School
Co-authored papers 3
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Johns Hopkins University School of Medicine
Co-authored papers 2
Clinical Genetics Branch, National Cancer Institute
Co-authored papers 2
Brain Tumor Institute, Children's National Hospital
Co-authored papers 2
Johns Hopkins University
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
Co-authored papers 2
Geisel School of Medicine, Dartmouth College
Co-authored papers 2
Verily Life Sciences LLC
Co-authored papers 1
Co-authored papers 1
Milken Institute School of Public Health, The George Washington University
Co-authored papers 1
Co-authored papers 1
National Institutes of Health
Co-authored papers 1
St George's University Hospitals NHS Foundation Trust
Co-authored papers 1
Murdoch Children's Research Institute
Co-authored papers 1
National Cancer Institute
Co-authored papers 1
Center for Law and the Biosciences, Stanford University
Co-authored papers 1
Children's Hospital Oakland Research Institute
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1