Author details

Full Name

Chiea Chuen Khor

Affiliation

ORCID

Career Start Year

2006

Papers

274

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37532769	Direct inference and control of genetic population structure from RNA sequencing data.		2023
36252563	Impact of Genetic Variants in the Nicotine Metabolism Pathway on Nicotine Metabolite Levels in Smokers.	Cancer Epidemiology Biomarkers and Prevention	2023
38039744	Rodent genetically modified models of glaucoma.		2023
38035998	APOE Genotype Modifies the Association between Midlife Adherence to the Planetary Healthy Diet and Cognitive Function in Later Life among Chinese Adults in Singapore.		2023
38028628	Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.	Front Genet	2023
37662190	Disruption of Aldehyde Dehydrogenase 2 protects against bacterial infection.	bioRxiv	2023
37787447	Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy.	J Am Soc Nephrol	2023
37477572	Third-Generation Single-Molecule Sequencing for Preimplantation Genetic Testing of Aneuploidy and Segmental Imbalances.	Clin Chem	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
36971353	Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study.		2023
37205491	The landscape of tolerated genetic variation in humans and primates.	bioRxiv	2023
36823694	MUC5AC Genetic Variation Is Associated With Tuberculous Meningitis Cerebral Spinal Fluid Cytokine Responses and Mortality.	J Infect Dis	2023
37262156	The landscape of tolerated genetic variation in humans and primates.	Science	2023
37262161	A global catalog of whole-genome diversity from 233 primate species.	Science	2023
36629403	Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations.	Clin Pharmacol Ther	2023
37123247	A five-safes approach to a secure and scalable genomics data repository.	iScience	2023
36797672	Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome.	BMC Genomics	2023
36797040	Identification of new risk loci shared across systemic vasculitides points towards potential target genes for drug repurposing.	Ann Rheum Dis	2023
36788305	Increased BMI and late-life mobility dysfunction; overlap of genetic effects in brain regions.		2023
35102304	Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.	Nat Microbiol	2022
36042462	Biallelic variants in CHST3 cause Spondyloepiphyseal dysplasia with joint dislocations in three Pakistani kindreds.	BMC Musculoskeletal Disorders	2022
35589495	The genetic basis for adult onset glaucoma: Recent advances and future directions.	Progress in Retinal and Eye Research	2022
35954343	Germline Variants Associated with Nasopharyngeal Carcinoma Predisposition Identified through Whole-Exome Sequencing.	Cancers (Basel)	2022
35697829	Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.	Commun Biol	2022
35503778	NAFLD polygenic risk score and risk of hepatocellular carcinoma in an East Asian population.	Hepatology Communications	2022
35817782	Examining the common and specific grey matter abnormalities in childhood maltreatment and peer victimisation.	BJPsych Open	2022
36341116	Case report: Expanding the phenotype of mutations from increased intracranial aneurysm risk to a neurodevelopmental disease.	Frontiers in Neurology	2022
35551603	The association of genetic susceptibility to smoking with cardiovascular disease mortality and the benefits of adhering to a DASH diet: The Singapore Chinese Health Study.	American Journal of Clinical Nutrition	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35927272	Genetic associations with healthy ageing among Chinese adults.		2022
35413122	Interaction between cigarette smoking and genetic polymorphisms on the associations with age of natural menopause and reproductive lifespan: the Singapore Chinese Health Study.	Human Reproduction	2022
36056160	Author Correction: Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.	Nat Microbiol	2022
35726449	A genomic-augmented multivariate prognostic model for the survival of natural-killer/T-cell lymphoma patients from an international cohort.	Am J Hematol	2022
35660961	Shortened Telomere Length in Sputum Cells of Bronchiectasis Patients is Associated with Dysfunctional Inflammatory Pathways.	Lung	2022
35468796	Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification.	BMC Medicine	2022
33993232	Identification of a shared genetic risk locus for Kawasaki disease and immunoglobulin A vasculitis by a cross-phenotype meta-analysis.	Rheumatology (Oxford)	2022
35217585	REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk.	J Immunol	2022
34906514	Polygenic risk scores for prediction of breast cancer risk in Asian populations.	Genet Med	2022
35022146	Functional coding haplotypes and machine-learning feature elimination identifies predictors of Methotrexate Response in Rheumatoid Arthritis patients.	eBioMedicine	2022
34763023	Association of the CYP39A1 G204E Genetic Variant with Increased Risk of Glaucoma and Blindness in Patients with Exfoliation Syndrome.	Ophthalmology	2022
34425738	Associations between , and polymorphisms and primary open angle glaucoma in Polish participants of European ancestry.	Ophthalmic Genetics	2022
35094058	Machine learning using genetic and clinical data identifies a signature that robustly predicts methotrexate response in rheumatoid arthritis.	Rheumatology	2022
34950780	Genetic susceptibility to hepatocellular carcinoma in chromosome 22q13.31, findings of a genome-wide association study.	JGH Open	2021
33792947	Variation in predicted COVID-19 risk among lemurs and lorises.	Am J Primatol	2021
33627673	Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries.	Nat Commun	2021
33620406	Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye.	JAMA	2021
33941849	Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.	Commun Biol	2021
33992511	The association of genetically determined serum glycine with cardiovascular risk in East Asians.	Nutrition, Metabolism and Cardiovascular Diseases	2021
33045076	Midlife Leukocyte Telomere Length as an Indicator for Handgrip Strength in Late Life.		2021
33137338	Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.	Kidney Int	2021