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Author Details

David F Burke
European Bioinformatics Institute (EMBL-EBI)
1997
59
33
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36690744Towards a structurally resolved human protein interaction network.Nat Struct Mol Biol2023
37800947Antigenic mapping of the hemagglutinin of the H9 subtype influenza A viruses using sera from Japanese quail (<i>Coturnix c. japonica</i>).J Virol2023
37565755Characterization of A/H7 influenza virus global antigenic diversity and key determinants in the hemagglutinin globular head mediating A/H7N9 antigenic evolution.mBio2023
37112987Structural Consequences of Antigenic Variants of Human A/H3N2 Influenza Viruses.Viruses2023
33563825Plasticity of the Influenza Virus H5 HA Protein.mBio2021
32287326Characterizing Emerging Canine H3 Influenza Viruses.PLoS Pathog2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
33102445Energy Landscape for the Membrane Fusion Pathway in Influenza A Hemagglutinin From Discrete Path Sampling.Front Chem2020
30355680Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition.J Virol2019
31017567Epistatic interactions can moderate the antigenic effect of substitutions in haemagglutinin of influenza H3N2 virus.J Gen Virol2019
30967460Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies.mBio2019
30700609The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza Viruses.J Virol2019
29855467Antigenic characterization of highly pathogenic avian influenza A(H5N1) viruses with chicken and ferret antisera reveals clade-dependent variation in hemagglutination inhibition profiles.Emerg Microbes Infect2018
27679478Influenza Research Database: An integrated bioinformatics resource for influenza virus research.Nucleic Acids Res2017
28792671Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.Influenza Other Respir Viruses2017
26792744Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus.J Virol2016
27113719The global antigenic diversity of swine influenza A viruses.Elife2016
27572841Selection of antigenically advanced variants of seasonal influenza viruses.Nat Microbiol2016
25609810Identification of amino acid substitutions supporting antigenic change of influenza A(H1N1)pdm09 viruses.J Virol2015
24522915Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine.J Virol2014
25418838Circulation of reassortant influenza A(H7N9) viruses in poultry and humans, Guangdong Province, China, 2013.Emerg Infect Dis2014
25391151A recommended numbering scheme for influenza A HA subtypes.PLoS One2014
25126555Polymorphisms at amino acid residues 141 and 154 influence conformational variation in ovine PrP.Biomed Res Int2014
24922572Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential.Cell Host Microbe2014
24917596Antigenic variation of clade 2.1 H5N1 virus is determined by a few amino acid substitutions immediately adjacent to the receptor binding site.mBio2014
23925116Limited airborne transmission of H7N9 influenza A virus between ferrets.Nature2013
24086684Quantifying the fitness advantage of polymerase substitutions in Influenza A/H7N9 viruses during adaptation to humans.PLoS One2013
24264991Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution.Science2013
22682293A review of influenza haemagglutinin receptor binding as it relates to pandemic properties.Vaccine2012
22723414The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.Science2012
22723413Airborne transmission of influenza A/H5N1 virus between ferrets.Science2012
21937642Antigenic and genetic evolution of equine influenza A (H3N8) virus from 1968 to 2007.J Virol2011
22143798Discordant antigenic drift of neuraminidase and hemagglutinin in H1N1 and H3N2 influenza viruses.Proc Natl Acad Sci U S A2011
20844044Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding.J Virol2010
19465683Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans.Science2009
18003615Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein.J Biol Chem2008
18237407Comparative modelling by restraint-based conformational sampling.BMC Struct Biol2008
17931166The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2.Biochem J2008
17341496Andante: reducing side-chain rotamer search space during comparative modeling using environment-specific substitution probabilities.Bioinformatics2007
18172930A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.J Bioinform Comput Biol2007
17708757Genome bioinformatic analysis of nonsynonymous SNPs.BMC Bioinformatics2007
16524830Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery.Philos Trans R Soc Lond B Biol Sci2006
15932902PROVAT: a tool for Voronoi tessellation analysis of protein structures and complexes.Bioinformatics2005
16252284Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations.Proteins2005
12596261Ab initio construction of polypeptide fragments: Accuracy of loop decoy discrimination by an all-atom statistical potential and the AMBER force field with the Generalized Born solvation model.Proteins2003
12682062A novel type of deubiquitinating enzyme.J Biol Chem2003
11522920Improved protein loop prediction from sequence alone.Protein Eng2001
11835486Sequence-structure homology recognition by iterative alignment refinement and comparative modeling.Proteins2001
11457455Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution.FEBS Lett2001
11524380HOMSTRAD: adding sequence information to structure-based alignments of homologous protein families.Bioinformatics2001
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Collaborators

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Influenza Research Institute, University of Wisconsin-Madison
Co-authored papers 5
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Co-authored papers 2
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Co-authored papers 2
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
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Co-authored papers 2
Indian Institute of Science
Co-authored papers 2
Erasmus Medical Center
Co-authored papers 2
Influenza Research Institute, University of Wisconsin
Co-authored papers 2
Co-authored papers 2
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 2
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European Bioinformatics Institute
Co-authored papers 2
Drukier Institute for Children's Health
Co-authored papers 2
University of California San Francisco
Co-authored papers 1
School of Clinical Medicine, University of Hong Kong
Co-authored papers 1
College of Life Sciences, University of Dundee
Co-authored papers 1
The University of Kansas
Co-authored papers 1
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Quantitative Biosciences Institute (QBI), University of California San Francisco
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ETH Zurich
Co-authored papers 1
Quantitative Biosciences Institute (QBI), University of California san francisco
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University of California san francisco
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