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Author Details
Full Name
David F Burke
Affiliation
European Bioinformatics Institute (EMBL-EBI)
ORCID
Career Start Year
1997
Papers
59
H Index
33
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36690744
Towards a structurally resolved human protein interaction network.
Nat Struct Mol Biol
2023
37800947
Antigenic mapping of the hemagglutinin of the H9 subtype influenza A viruses using sera from Japanese quail (<i>Coturnix c. japonica</i>).
J Virol
2023
37565755
Characterization of A/H7 influenza virus global antigenic diversity and key determinants in the hemagglutinin globular head mediating A/H7N9 antigenic evolution.
mBio
2023
37112987
Structural Consequences of Antigenic Variants of Human A/H3N2 Influenza Viruses.
Viruses
2023
33563825
Plasticity of the Influenza Virus H5 HA Protein.
mBio
2021
32287326
Characterizing Emerging Canine H3 Influenza Viruses.
PLoS Pathog
2020
33060197
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science
2020
33102445
Energy Landscape for the Membrane Fusion Pathway in Influenza A Hemagglutinin From Discrete Path Sampling.
Front Chem
2020
30355680
Plasticity of Amino Acid Residue 145 Near the Receptor Binding Site of H3 Swine Influenza A Viruses and Its Impact on Receptor Binding and Antibody Recognition.
J Virol
2019
31017567
Epistatic interactions can moderate the antigenic effect of substitutions in haemagglutinin of influenza H3N2 virus.
J Gen Virol
2019
30967460
Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies.
mBio
2019
30700609
The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza Viruses.
J Virol
2019
29855467
Antigenic characterization of highly pathogenic avian influenza A(H5N1) viruses with chicken and ferret antisera reveals clade-dependent variation in hemagglutination inhibition profiles.
Emerg Microbes Infect
2018
27679478
Influenza Research Database: An integrated bioinformatics resource for influenza virus research.
Nucleic Acids Res
2017
28792671
Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.
Influenza Other Respir Viruses
2017
26792744
Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus.
J Virol
2016
27113719
The global antigenic diversity of swine influenza A viruses.
Elife
2016
27572841
Selection of antigenically advanced variants of seasonal influenza viruses.
Nat Microbiol
2016
25609810
Identification of amino acid substitutions supporting antigenic change of influenza A(H1N1)pdm09 viruses.
J Virol
2015
24522915
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine.
J Virol
2014
25418838
Circulation of reassortant influenza A(H7N9) viruses in poultry and humans, Guangdong Province, China, 2013.
Emerg Infect Dis
2014
25391151
A recommended numbering scheme for influenza A HA subtypes.
PLoS One
2014
25126555
Polymorphisms at amino acid residues 141 and 154 influence conformational variation in ovine PrP.
Biomed Res Int
2014
24922572
Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential.
Cell Host Microbe
2014
24917596
Antigenic variation of clade 2.1 H5N1 virus is determined by a few amino acid substitutions immediately adjacent to the receptor binding site.
mBio
2014
23925116
Limited airborne transmission of H7N9 influenza A virus between ferrets.
Nature
2013
24086684
Quantifying the fitness advantage of polymerase substitutions in Influenza A/H7N9 viruses during adaptation to humans.
PLoS One
2013
24264991
Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution.
Science
2013
22682293
A review of influenza haemagglutinin receptor binding as it relates to pandemic properties.
Vaccine
2012
22723414
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host.
Science
2012
22723413
Airborne transmission of influenza A/H5N1 virus between ferrets.
Science
2012
21937642
Antigenic and genetic evolution of equine influenza A (H3N8) virus from 1968 to 2007.
J Virol
2011
22143798
Discordant antigenic drift of neuraminidase and hemagglutinin in H1N1 and H3N2 influenza viruses.
Proc Natl Acad Sci U S A
2011
20844044
Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding.
J Virol
2010
19465683
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans.
Science
2009
18003615
Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein.
J Biol Chem
2008
18237407
Comparative modelling by restraint-based conformational sampling.
BMC Struct Biol
2008
17931166
The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2.
Biochem J
2008
17341496
Andante: reducing side-chain rotamer search space during comparative modeling using environment-specific substitution probabilities.
Bioinformatics
2007
18172930
A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.
J Bioinform Comput Biol
2007
17708757
Genome bioinformatic analysis of nonsynonymous SNPs.
BMC Bioinformatics
2007
16524830
Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery.
Philos Trans R Soc Lond B Biol Sci
2006
15932902
PROVAT: a tool for Voronoi tessellation analysis of protein structures and complexes.
Bioinformatics
2005
16252284
Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations.
Proteins
2005
12596261
Ab initio construction of polypeptide fragments: Accuracy of loop decoy discrimination by an all-atom statistical potential and the AMBER force field with the Generalized Born solvation model.
Proteins
2003
12682062
A novel type of deubiquitinating enzyme.
J Biol Chem
2003
11522920
Improved protein loop prediction from sequence alone.
Protein Eng
2001
11835486
Sequence-structure homology recognition by iterative alignment refinement and comparative modeling.
Proteins
2001
11457455
Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution.
FEBS Lett
2001
11524380
HOMSTRAD: adding sequence information to structure-based alignments of homologous protein families.
Bioinformatics
2001
1 - 50 of 59
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